Interactor 1: RPTOR (Q8N122)
Regulatory-associated protein of mTOR (Raptor) (p150 target of rapamycin (TOR)-scaffold protein)
Gene: RPTOR

Interactor 2: SYLC (Q9P2J5)
Leucine--tRNA ligase, cytoplasmic (EC 6.1.1.4) (Leucyl-tRNA synthetase) (LeuRS) (cLRS)
Gene: LARS1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.51 0.60 0.558

The method score is based on:

Property Details
Experiments 22424946
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation, fluorescence microscopy, anti bait coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005737 - cytoplasm
GO:0005764 - lysosome
GO:0005829 - cytosol
GO:0008361 - regulation of cell size
GO:0032008 - positive regulation of TOR signaling
and 2 others

more...

Homologous interactions 5

Homologous interactions

Color coding for hit scores

1 1335
Hs

1 1176
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024