HitPredict

Interactor 1: MEN1 (O00255)
Menin
Gene: MEN1

Interactor 2: ASH2L (Q9UBL3)
Set1/Ash2 histone methyltransferase complex subunit ASH2 (ASH2-like protein)
Gene: ASH2L

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.91 0.60 0.741

The method score is based on:

Property Details
Experiments 23508102, 35850772, 17050672, 14992727, 15199122, 24981860, 37974198
Identification Methods affinity chromatography technology, pull down, tandem affinity purification
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000976 - transcription cis-regulatory region binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0006974 - DNA damage response
GO:0035097 - histone methyltransferase complex
and 4 others

more...
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 610
Hs

1 628
+ Hs
+ Dm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024