HitPredict

Interactor 1: CBX4 (O00257)
E3 SUMO-protein ligase CBX4 (EC 2.3.2.-) (Chromobox protein homolog 4) (Polycomb 2 homolog) (Pc2) (hPc2)
Gene: CBX4

Interactor 2: TOX4 (O94842)
TOX high mobility group box family member 4 (Epidermal Langerhans cell protein LCP1)
Gene: TOX4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	24981860
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 560 Hs			1 621
+	Hs
		123201 CBX4_HUMAN (1-560): 7.58e-163: 477: 100.00		SOX2_HUMAN (185-480): 3.81e-31: 125: 13.61
+	Hs
		996854 MPP8_HUMAN (6-431): 5.25e-87: 289: 13.72		SSRP1_HUMAN (148-386): 3.7e-29: 124: 18.11
+	Hs
		818053 CBX2_HUMAN (2-559): 1.19e-82: 269: 23.54		SOX2_HUMAN (185-480): 3.81e-31: 125: 13.61
+	Hs
		996672 CBX2_HUMAN (2-559): 1.19e-82: 269: 23.54		SSRP1_HUMAN (148-386): 3.7e-29: 124: 18.11
+	Hs
		1027314 CBX3_HUMAN (9-163): 8.8e-44: 155: 21.94		HMGX4_HUMAN (55-335): 2.61e-40: 157: 20.41
+	Hs
		996646 CBX3_HUMAN (9-163): 8.8e-44: 155: 21.94		SSRP1_HUMAN (148-386): 3.7e-29: 124: 18.11
+	Hs
		643340 CBX3_HUMAN (9-163): 8.8e-44: 155: 21.94		HMGB2_HUMAN (139-314): 2.31e-31: 123: 18.38
+	Mm
		818771 Q9DCC5_MOUSE (9-163): 8.8e-44: 155: 21.94		SOX2_MOUSE (186-480): 7.81e-30: 121: 13.02
+	Hs
		175775 CBX3_HUMAN (9-163): 8.8e-44: 155: 21.94		HMGB3_HUMAN (150-309): 1.59e-29: 117: 20.96
+	Mm
		818718 CBX5_MOUSE (11-169): 3.2e-41: 149: 20.71		SOX2_MOUSE (186-480): 7.81e-30: 121: 13.02
+	Hs
		449706 CBX3_HUMAN (9-163): 8.8e-44: 155: 21.94		HMGB1_HUMAN (139-302): 5.39e-28: 113: 20.23
+	Mm
		818693 CBX1_MOUSE (17-163): 1.89e-39: 144: 21.05		SOX2_MOUSE (186-480): 7.81e-30: 121: 13.02
+	Dm
		1363173 Q9VCU6_DROME (8-232): 1.42e-35: 135: 22.81		Q9VUD3_DROME (216-333): 3.05e-30: 127: 21.67
+	Dm
		114467 Q9VCU6_DROME (8-232): 1.42e-35: 135: 22.81		M9PCG2_DROME (216-333): 1.35e-29: 125: 21.67
+	Hs
		617293 CBX3_HUMAN (9-163): 8.8e-44: 155: 21.94		SP100_HUMAN (164-303): 3.95e-21: 100: 24.83
+	Hs
		617254 CBX5_HUMAN (11-171): 7.04e-41: 148: 19.88		SP100_HUMAN (164-303): 3.95e-21: 100: 24.83
+	Hs
		617403 V9HWG0_HUMAN (11-171): 7.04e-41: 148: 19.88		SP100_HUMAN (164-303): 3.95e-21: 100: 24.83
+	Hs
		617284 CBX1_HUMAN (17-163): 1.89e-39: 144: 21.05		SP100_HUMAN (164-303): 3.95e-21: 100: 24.83