Protein: ERF3B
Eukaryotic peptide chain release factor GTP-binding subunit ERF3B (Eukaryotic peptide chain release factor subunit 3b) (eRF3b) (EC 3.6.5.-) (G1 to S phase transition protein 2 homolog)

Gene: ERF3B, GSPT2
Organism: Homo sapiens
Interactions: 90
UniProt ID: Q8IYD1

Gene Ontology (top 5):
GO:0000184 - nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
GO:0003723 - RNA binding
GO:0003747 - translation release factor activity
GO:0003924 - GTPase activity
GO:0005525 - GTP binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

516584

PABP1
Polyadenylate-binding protein 1

7

8

Small-scale

0.974

High

914547

ERF1
Eukaryotic peptide chain release factor subunit 1

5

8

Small-scale

0.930

High

545882

ERF3A
Eukaryotic peptide chain release factor GTP-binding subunit ERF3A

4

11

High-throughput

0.903

High

1031386

PABP4
Polyadenylate-binding protein 4

2

8

High-throughput

0.811

High

1222965

RENT1
Regulator of nonsense transcripts 1

4

7

Small-scale

0.710

High

1119139

PAP1L
Polyadenylate-binding protein 1-like

1

8

High-throughput

0.691

High

128234

IF2B3
Insulin-like growth factor 2 mRNA-binding protein 3

2

11

High-throughput

0.628

High

172879

CASC3
Protein CASC3

2

2

High-throughput

0.628

High

432807

HNRPC
Heterogeneous nuclear ribonucleoproteins C1/C2

2

6

High-throughput

0.628

High

834080

CLK3
Dual specificity protein kinase CLK3

2

4

High-throughput

0.628

High

998117

NCBP1
Nuclear cap-binding protein subunit 1

2

2

High-throughput

0.628

High

1020291

ELAV2
ELAV-like protein 2

2

9

High-throughput

0.628

High

1145685

LAR1B
La-related protein 1B

2

5

High-throughput

0.628

High

1162604

LARP1
La-related protein 1

2

5

High-throughput

0.628

High

1183936

DHX30
ATP-dependent RNA helicase DHX30

2

7

High-throughput

0.628

High

1201533

ZCH18
Zinc finger CCCH domain-containing protein 18

2

8

High-throughput

0.628

High

1222963

PI42C
Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma

2

1

High-throughput

0.628

High

1222964

SRS12
Serine/arginine-rich splicing factor 12

2

10

High-throughput

0.628

High

1222968

YTDC1
YTH domain-containing protein 1

2

1

High-throughput

0.628

High

1222977

MOV10
Helicase MOV-10

2

7

High-throughput

0.628

High

1222978

ZCHC3
Zinc finger CCHC domain-containing protein 3

2

2

High-throughput

0.628

High

304241

UBR5
E3 ubiquitin-protein ligase UBR5

1

8

Small-scale

0.618

High

256546

ZC11A
Zinc finger CCCH domain-containing protein 11A

2

0

High-throughput

0.602

High

1048579

PDE1C
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C

2

0

High-throughput

0.602

High

1120393

NCBP3
Nuclear cap-binding protein subunit 3

2

0

High-throughput

0.602

High

1222983

F120A
Constitutive coactivator of PPAR-gamma-like protein 1

2

0

High-throughput

0.602

High

833919

CLK2
Dual specificity protein kinase CLK2

2

4

High-throughput

0.574

High

474030

PAB4L
Polyadenylate-binding protein 4-like

2

8

High-throughput

0.552

High

165524

SR140
U2 snRNP-associated SURP motif-containing protein

1

10

High-throughput

0.536

High

216945

KIF1C
Kinesin-like protein KIF1C

1

1

High-throughput

0.536

High

267021

SRS10
Serine/arginine-rich splicing factor 10

1

11

High-throughput

0.536

High

322865

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

9

High-throughput

0.536

High

563145

YBOX3
Y-box-binding protein 3

1

2

High-throughput

0.536

High

816821

IREB2
Iron-responsive element-binding protein 2

1

2

High-throughput

0.536

High

899519

MGN
Protein mago nashi homolog

1

2

High-throughput

0.536

High

925070

TRA2B
Transformer-2 protein homolog beta

1

12

High-throughput

0.536

High

931269

YBOX1
Y-box-binding protein 1

1

2

High-throughput

0.536

High

992841

SRSF1
Serine/arginine-rich splicing factor 1

1

10

High-throughput

0.536

High

1023503

MKRN3
Probable E3 ubiquitin-protein ligase makorin-3

1

2

High-throughput

0.536

High

1040358

TRA2A
Transformer-2 protein homolog alpha

1

10

High-throughput

0.536

High

1056690

PUM1
Pumilio homolog 1

1

6

High-throughput

0.536

High

1070546

RNPS1
RNA-binding protein with serine-rich domain 1

1

11

High-throughput

0.536

High

1073797

RBMS2
RNA-binding motif, single-stranded-interacting protein 2

1

11

High-throughput

0.536

High

1174816

LARP4
La-related protein 4

1

6

High-throughput

0.536

High

1191688

RBBP6
E3 ubiquitin-protein ligase RBBP6

1

6

High-throughput

0.536

High

1216940

ABC3F
DNA dC->dU-editing enzyme APOBEC-3F

1

2

High-throughput

0.536

High

1222962

PUM2
Pumilio homolog 2

1

6

High-throughput

0.536

High

1222967

ZFR
Zinc finger RNA-binding protein

1

4

High-throughput

0.536

High

1222969

RBM14
RNA-binding protein 14

1

10

High-throughput

0.536

High

1222970

SMG1
Serine/threonine-protein kinase SMG1

1

1

Small-scale

0.536

High

1222971

ATX2
Ataxin-2

1

4

High-throughput

0.536

High

1222973

PAIP1
Polyadenylate-binding protein-interacting protein 1

1

5

High-throughput

0.536

High

1222975

DHX36
ATP-dependent DNA/RNA helicase DHX36

1

11

High-throughput

0.536

High

1222976

PININ
Pinin

1

1

High-throughput

0.536

High

1222980

STAU2
Double-stranded RNA-binding protein Staufen homolog 2

1

9

High-throughput

0.536

High

1222982

BCLF1
Bcl-2-associated transcription factor 1

1

6

High-throughput

0.536

High

1222984

IF2B1
Insulin-like growth factor 2 mRNA-binding protein 1

1

7

High-throughput

0.536

High

1222987

ABC3B
DNA dC->dU-editing enzyme APOBEC-3B

1

2

High-throughput

0.536

High

1222988

MKRN1
E3 ubiquitin-protein ligase makorin-1

1

4

High-throughput

0.536

High

1222989

RALY
RNA-binding protein Raly

1

1

High-throughput

0.536

High

1222991

SRRM2
Serine/arginine repetitive matrix protein 2

1

9

High-throughput

0.536

High

1222992

TR150
Thyroid hormone receptor-associated protein 3

1

8

High-throughput

0.536

High

1222994

IF2B2
Insulin-like growth factor 2 mRNA-binding protein 2

1

10

High-throughput

0.536

High

1124902

ZN326
DBIRD complex subunit ZNF326

1

0

High-throughput

0.513

High

1220016

SUGP2
SURP and G-patch domain-containing protein 2

1

0

High-throughput

0.513

High

395144

A4
Amyloid-beta precursor protein

1

2

High-throughput

0.501

High

1222974

NUAK2
NUAK family SNF1-like kinase 2

1

4

High-throughput

0.489

High

228009

PRKN
E3 ubiquitin-protein ligase parkin

1

13

High-throughput

0.479

High

674332

PURA2
Adenylosuccinate synthetase isozyme 2

1

1

High-throughput

0.479

High

908796

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

5

High-throughput

0.479

High

918509

H2B1C
Histone H2B type 1-C/E/F/G/I

1

8

High-throughput

0.479

High

928774

RL38
Large ribosomal subunit protein eL38

1

1

High-throughput

0.479

High

973133

RL6
Large ribosomal subunit protein eL6

1

3

High-throughput

0.479

High

1063940

TNIP1
TNFAIP3-interacting protein 1

1

6

High-throughput

0.479

High

1222972

TRI31
E3 ubiquitin-protein ligase TRIM31

1

2

High-throughput

0.479

High

1222985

HDAC6
Histone deacetylase 6

1

6

High-throughput

0.479

High

1222986

ZRAN1
Ubiquitin thioesterase ZRANB1

1

4

High-throughput

0.479

High

1222990

RL26L
Ribosomal protein uL24-like

1

4

High-throughput

0.479

High

298641

UFL1
E3 UFM1-protein ligase 1

1

0

High-throughput

0.458

High

497278

TAU
Microtubule-associated protein tau

1

8

High-throughput

0.445

High

347286

MYC
Myc proto-oncogene protein

1

9

High-throughput

0.437

High

379598

MYCN
N-myc proto-oncogene protein

1

9

High-throughput

0.437

High

393272

AT1A1
Sodium/potassium-transporting ATPase subunit alpha-1

1

1

High-throughput

0.437

High

1170742

TRI67
Tripartite motif-containing protein 67

1

8

High-throughput

0.437

High

1174258

MOB3C
MOB kinase activator 3C

1

1

High-throughput

0.437

High

1222961

ZDH23
Palmitoyltransferase ZDHHC23

1

2

Small-scale

0.437

High

1222966

DDRGK
DDRGK domain-containing protein 1

1

2

High-throughput

0.437

High

1222979

ZDH18
Palmitoyltransferase ZDHHC18

1

1

Small-scale

0.437

High

1222981

PIHD1
PIH1 domain-containing protein 1

1

1

High-throughput

0.437

High

1222993

AAR2
Protein AAR2 homolog

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024