Interactor 1: PELI3 (Q8N2H9)
E3 ubiquitin-protein ligase pellino homolog 3 (Pellino-3) (EC 2.3.2.27)
Gene: PELI3

Interactor 2: TRAF6 (Q9Y4K3)
TNF receptor-associated factor 6 (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRAF6) (Interleukin-1 signal transducer) (RING finger protein 85) (RING-type E3 ubiquitin transferase TRAF6)
Gene: TRAF6

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.85 0.60 0.718

The method score is based on:

Property Details
Experiments 12874243, 23042151, 25027698, 18326498, 15917247
Identification Methods affinity chromatography technology, enzymatic study, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005829 - cytosol
GO:0045087 - innate immune response
GO:0061630 - ubiquitin protein ligase activity
GO:0070534 - protein K63-linked ubiquitination
Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 469
Hs

1 522
+ Hs
+ Hs
+ Hs

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Last updated: 15 Jul 2024