HitPredict

Interactor 1: STK40 (Q8N2I9)
Serine/threonine-protein kinase 40 (EC 2.7.11.1) (SINK-homologous serine/threonine-protein kinase) (Sugen kinase 495) (SgK495)
Gene: STK40

Interactor 2: MTCL1 (Q9Y4B5)
Microtubule cross-linking factor 1 (Coiled-coil domain-containing protein 165) (PAR-1-interacting protein) (SOGA family member 2)
Gene: MTCL1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	28089446
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 435 Hs			1 1905
+	Hs
		1183156 MARK2_HUMAN (7-422): 6.04e-122: 374: 20.34		MTCL1_HUMAN (1-1905): 0: 827: 100.00
+	Hs
		1296792 MARK4_HUMAN (4-433): 6.72e-122: 373: 20.32		MTCL1_HUMAN (1-1905): 0: 827: 100.00
+	Hs
		647995 MARK3_HUMAN (3-433): 6.07e-121: 370: 19.55		MTCL1_HUMAN (1-1905): 0: 827: 100.00
+	Hs
		725223 MARK4_HUMAN (4-433): 6.72e-122: 373: 20.32		MYH10_HUMAN (127-797): 1.09e-16: 89: 10.88
+	Hs
		301300 MARK2_HUMAN (7-422): 6.04e-122: 374: 20.34		MTCL2_HUMAN (52-1172): 3.52e-13: 77.4: 10.52
+	Hs
		301316 MARK4_HUMAN (4-433): 6.72e-122: 373: 20.32		MTCL2_HUMAN (52-1172): 3.52e-13: 77.4: 10.52
+	Hs
		301264 MARK3_HUMAN (3-433): 6.07e-121: 370: 19.55		MTCL2_HUMAN (52-1172): 3.52e-13: 77.4: 10.52
+	Hs
		724967 MARK4_HUMAN (4-433): 6.72e-122: 373: 20.32		MYH9_HUMAN (171-636): 9.75e-11: 69.3: 10.04
+	Hs
		681881 AKT1_HUMAN (6-401): 2.8e-119: 358: 21.14		GRDN_HUMAN (309-722): 1.56e-14: 81.9: 20.40
+	Mm
		682109 AKT1_MOUSE (6-401): 5.44e-120: 360: 21.14		GRDN_MOUSE (338-1203): 4.58e-13: 77.3: 16.57
+	Mm
		1130947 AKT2_MOUSE (9-401): 1.01e-119: 359: 21.36		GRDN_MOUSE (338-1203): 4.58e-13: 77.3: 16.57
+	Hs
		551616 AKT1_HUMAN (6-401): 2.8e-119: 358: 21.14		DESP_HUMAN (294-843): 6.21e-12: 73.4: 16.70
+	Hs
		623875 KPCL_HUMAN (4-400): 1.59e-118: 362: 20.60		PLEC_HUMAN (321-1278): 1.45e-09: 65.7: 16.15
+	Hs
		681696 AKT1_HUMAN (6-401): 2.8e-119: 358: 21.14		MYH9_HUMAN (171-636): 9.75e-11: 69.3: 10.04
+	Mm
		554901 KPCE_MOUSE (2-400): 5.42e-96: 305: 20.83		MYH6_MOUSE (849-1542): 3.14e-24: 114: 8.76
+	Mm
		554927 KPCE_MOUSE (2-400): 5.42e-96: 305: 20.83		MYH7_MOUSE (157-813): 2.51e-17: 91.3: 10.23
+	Hs
		725226 TRIB3_HUMAN (161-325): 4.49e-25: 107: 38.10		MYH10_HUMAN (127-797): 1.09e-16: 89: 10.88
+	Rn
		102485 AAPK1_RAT (162-326): 1e-22: 102: 33.94		G3V6P7_RAT (162-700): 2.35e-13: 78.2: 11.09
+	Hs
		301284 AAPK1_HUMAN (162-326): 1.02e-22: 102: 33.94		MTCL2_HUMAN (52-1172): 3.52e-13: 77.4: 10.52
+	Hs
		724974 TRIB3_HUMAN (161-325): 4.49e-25: 107: 38.10		MYH9_HUMAN (171-636): 9.75e-11: 69.3: 10.04