Protein: DBP3
ATP-dependent RNA helicase DBP3 (EC 3.6.4.13) (DEAD box protein 3) (Helicase CA3)

Gene: DBP3
Organism: Saccharomyces cerevisiae S288C
Interactions: 111
UniProt ID: P20447

Gene Ontology (top 5):
GO:0000464 - endonucleolytic cleavage in ITS1 upstream of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0003724 - RNA helicase activity
GO:0003729 - mRNA binding
GO:0005524 - ATP binding
GO:0005730 - nucleolus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

632541

NHP2
H/ACA ribonucleoprotein complex subunit NHP2

2

4

High-throughput

0.789

High

632525

PWP1
Periodic tryptophan protein 1

1

15

High-throughput

0.698

High

632555

GBLP
Small ribosomal subunit protein RACK1

2

11

Small-scale

0.675

High

632536

GAR1
H/ACA ribonucleoprotein complex subunit GAR1

3

2

High-throughput

0.672

High

632524

DBP3
ATP-dependent RNA helicase DBP3

1

14

High-throughput

0.665

High

632564

SNU13
13 kDa ribonucleoprotein-associated protein

1

4

High-throughput

0.665

High

632548

CBF5
H/ACA ribonucleoprotein complex subunit CBF5

3

1

High-throughput

0.657

High

632609

NOP56
Nucleolar protein 56

3

3

High-throughput

0.657

High

632567

MPH1
ATP-dependent DNA helicase MPH1

1

17

Small-scale

0.621

High

632552

DBP7
ATP-dependent RNA helicase DBP7

1

15

Small-scale

0.618

High

632556

MAK5
ATP-dependent RNA helicase MAK5

1

15

Small-scale

0.618

High

632561

DHH1
ATP-dependent RNA helicase DHH1

1

17

High-throughput

0.618

High

632563

IF4F1
Eukaryotic initiation factor 4F subunit p150

1

6

Small-scale

0.618

High

632573

MTR4
ATP-dependent RNA helicase DOB1

1

14

Small-scale

0.618

High

632576

PRP43
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP43

1

6

High-throughput

0.618

High

632591

DHR1
Probable ATP-dependent RNA helicase DHR1

1

10

High-throughput

0.618

High

632596

HRQ1
ATP-dependent helicase HRQ1

1

17

Small-scale

0.618

High

632608

DBP10
ATP-dependent RNA helicase DBP10

1

17

High-throughput

0.618

High

585202

FBRL
rRNA 2'-O-methyltransferase fibrillarin

2

1

High-throughput

0.612

High

632531

KRR1
KRR1 small subunit processome component

2

2

High-throughput

0.601

High

632534

NSR1
Nuclear localization sequence-binding protein

2

14

High-throughput

0.601

High

632558

ENP1
Essential nuclear protein 1

2

3

High-throughput

0.584

High

594179

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

1

High-throughput

0.553

High

632526

RPA2
DNA-directed RNA polymerase I subunit RPA135

1

2

High-throughput

0.553

High

632575

RS12
Small ribosomal subunit protein eS12

1

2

High-throughput

0.553

High

632538

BMH1
Protein BMH1

2

4

High-throughput

0.549

High

632581

BRE5
UBP3-associated protein BRE5

1

5

High-throughput

0.536

High

632586

UBP3
Ubiquitin carboxyl-terminal hydrolase 3

1

11

High-throughput

0.536

High

632611

NOP10
H/ACA ribonucleoprotein complex subunit NOP10

1

1

High-throughput

0.515

High

632607

SMT3
Ubiquitin-like protein SMT3

1

5

High-throughput

0.504

High

632585

HPC2
Histone promoter control protein 2

1

5

High-throughput

0.494

High

632570

KRI1
Protein KRI1

1

0

High-throughput

0.493

High

454396

PHO4
Phosphate system positive regulatory protein PHO4

1

1

High-throughput

0.489

High

632539

XPO1
Exportin-1

1

12

High-throughput

0.489

High

632606

RIO1
Serine/threonine-protein kinase RIO1

1

8

Small-scale

0.481

High

149578

RS9A
Small ribosomal subunit protein uS4A

1

3

High-throughput

0.479

High

409929

RL25
Large ribosomal subunit protein uL23

1

3

High-throughput

0.479

High

435767

RS13
Small ribosomal subunit protein uS15

1

3

High-throughput

0.479

High

441699

RS14A
Small ribosomal subunit protein uS11A

1

2

High-throughput

0.479

High

512251

RS6A
Small ribosomal subunit protein eS6A

1

3

High-throughput

0.479

High

578825

HSC82
ATP-dependent molecular chaperone HSC82

1

4

High-throughput

0.479

High

632528

SIS1
Protein SIS1

1

3

High-throughput

0.479

High

632529

RRP43
Exosome complex component RRP43

1

1

High-throughput

0.479

High

632530

RS2
Small ribosomal subunit protein uS5

1

4

High-throughput

0.479

High

632532

CDC48
Cell division control protein 48

1

6

High-throughput

0.479

High

632533

RS7A
Small ribosomal subunit protein eS7A

1

3

High-throughput

0.479

High

632535

SPT5
Transcription elongation factor SPT5

1

3

High-throughput

0.479

High

632553

LAS1
Protein LAS1

1

1

Small-scale

0.479

High

632559

RS20
Small ribosomal subunit protein uS10

1

4

High-throughput

0.479

High

632569

RLP7
Ribosome biogenesis protein RLP7

1

4

High-throughput

0.479

High

632571

UTP10
U3 small nucleolar RNA-associated protein 10

1

2

High-throughput

0.479

High

632579

PESC
Pescadillo homolog

1

3

High-throughput

0.479

High

632580

TR112
Multifunctional methyltransferase subunit TRM112

1

1

Small-scale

0.479

High

632588

XRN2
5'-3' exoribonuclease 2

1

3

High-throughput

0.479

High

632590

TOM1
E3 ubiquitin-protein ligase TOM1

1

8

High-throughput

0.479

High

632595

RRP5
rRNA biogenesis protein RRP5

1

5

High-throughput

0.479

High

632598

NOC4
Nucleolar complex protein 4

1

4

High-throughput

0.479

High

632603

MLH3
DNA mismatch repair protein MLH3

1

1

High-throughput

0.479

High

632605

MAK21
Ribosome biogenesis protein MAK21

1

4

High-throughput

0.479

High

632610

NOP58
Nucleolar protein 58

1

3

High-throughput

0.479

High

632547

PRS6A
26S proteasome regulatory subunit 6A

1

0

High-throughput

0.458

High

632550

URB1
Nucleolar pre-ribosomal-associated protein 1

1

0

Small-scale

0.458

High

632593

UTP14
U3 small nucleolar RNA-associated protein 14

1

0

High-throughput

0.458

High

632604

YL11B
Transposon Ty1-LR1 Gag-Pol polyprotein

1

0

High-throughput

0.458

High

523029

HSP71
Heat shock protein SSA1

1

8

High-throughput

0.445

High

543786

SSB1
Ribosome-associated molecular chaperone SSB1

1

9

High-throughput

0.445

High

632543

HSP7F
Heat shock protein homolog SSE1

1

10

High-throughput

0.445

High

632565

SSB2
Ribosome-associated molecular chaperone SSB2

1

9

High-throughput

0.445

High

632584

SEN1
Helicase SEN1

1

4

Small-scale

0.445

High

383514

RS17A
Small ribosomal subunit protein eS17A

1

3

High-throughput

0.437

High

433442

RL26A
Large ribosomal subunit protein uL24A

1

3

High-throughput

0.437

High

434815

RS3
Small ribosomal subunit protein uS3

1

2

High-throughput

0.437

High

436315

RS31
Ubiquitin-ribosomal protein eS31 fusion protein [Cleaved into: Ubiquitin; Small ribosomal subunit protein eS31

1

2

High-throughput

0.437

High

454869

RS19A
Small ribosomal subunit protein eS19A

1

4

High-throughput

0.437

High

502845

RS22A
Small ribosomal subunit protein uS8A

1

3

High-throughput

0.437

High

504034

RL31A
Large ribosomal subunit protein eL31A

1

4

High-throughput

0.437

High

512813

RS8A
Small ribosomal subunit protein eS8A

1

2

High-throughput

0.437

High

514451

RS18A
Small ribosomal subunit protein uS13A

1

2

High-throughput

0.437

High

558575

CAF20
Cap-associated protein CAF20

1

2

High-throughput

0.437

High

632527

SAN1
Protein SAN1

1

1

Small-scale

0.437

High

632537

TF2B
Transcription initiation factor IIB

1

4

High-throughput

0.437

High

632540

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

1

High-throughput

0.437

High

632544

GSP1
GTP-binding nuclear protein GSP1/CNR1

1

2

High-throughput

0.437

High

632545

RSSA1
Small ribosomal subunit protein uS2A

1

5

High-throughput

0.437

High

632546

SMY2
Protein SMY2

1

1

High-throughput

0.437

High

632549

RS3A1
Small ribosomal subunit protein eS1A

1

3

High-throughput

0.437

High

632551

RS27A
Small ribosomal subunit protein eS27A

1

2

High-throughput

0.437

High

632562

LAA1
AP-1 accessory protein LAA1

1

3

High-throughput

0.437

High

632566

MLP2
Protein MLP2

1

7

High-throughput

0.437

High

632568

DSN1
Kinetochore-associated protein DSN1

1

2

High-throughput

0.437

High

632572

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

1

12

High-throughput

0.437

High

632582

APJ1
J domain-containing protein APJ1

1

3

High-throughput

0.437

High

632583

NUM1
Nuclear migration protein NUM1

1

1

High-throughput

0.437

High

632587

RS15
Small ribosomal subunit protein uS19

1

2

High-throughput

0.437

High

632592

VMS1
tRNA endonuclease VMS1

1

1

High-throughput

0.437

High

632594

POB3
FACT complex subunit POB3

1

5

High-throughput

0.437

High

632597

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

1

High-throughput

0.437

High

632599

VAM6
Vacuolar morphogenesis protein 6

1

2

High-throughput

0.437

High

632600

SGO1
Shugoshin

1

2

High-throughput

0.437

High

632601

RS10A
Small ribosomal subunit protein eS10A

1

2

High-throughput

0.437

High

632602

NCBP2
Nuclear cap-binding protein subunit 2

1

11

High-throughput

0.437

High

632554

RPF2
Ribosome biogenesis protein RPF2

1

0

High-throughput

0.426

High

632574

HLJ1
Protein HLJ1

1

1

High-throughput

0.407

High

632557

ATG12
Ubiquitin-like protein ATG12

2

0

High-throughput

0.295

High

357723

CYC7
Cytochrome c isoform 2

1

0

High-throughput

0.282

High

632560

DMA1
E3 ubiquitin-protein ligase DMA1

1

0

High-throughput

0.279

Low

632542

RPN12
26S proteasome regulatory subunit RPN12

1

0

High-throughput

0.269

Low

632577

DUO1
DASH complex subunit DUO1

1

0

High-throughput

0.249

Low

632589

FDC1
Ferulic acid decarboxylase 1

1

0

High-throughput

0.249

Low

632578

THG1
tRNA(His) guanylyltransferase

1

0

High-throughput

0.238

Low


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Last updated: 11Aug2025