Interactor 1: PIAS4 (Q8N2W9)
E3 SUMO-protein ligase PIAS4 (EC 2.3.2.27) (PIASy) (Protein inhibitor of activated STAT protein 4) (Protein inhibitor of activated STAT protein gamma) (PIAS-gamma)
Gene: PIAS4

Interactor 2: GFI1 (Q99684)
Zinc finger protein Gfi-1 (Growth factor independent protein 1) (Zinc finger protein 163)
Gene: GFI1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.53 0.60 0.565

The method score is based on:

Property Details
Experiments 19506020, 17636019
Identification Methods two hybrid
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0005634 - nucleus
GO:0006357 - regulation of transcription by RNA polymerase II
GO:0016363 - nuclear matrix
GO:0045892 - negative regulation of DNA-templated transcription
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 510
Hs

1 422
+ Hs
+ Mm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024