HitPredict

Interactor 1: CBX4 (O00257)
E3 SUMO-protein ligase CBX4 (EC 2.3.2.-) (Chromobox protein homolog 4) (Polycomb 2 homolog) (Pc2) (hPc2)
Gene: CBX4

Interactor 2: H2B1C (P62807)
Histone H2B type 1-C/E/F/G/I (Histone H2B.1 A) (Histone H2B.a) (H2B/a) (Histone H2B.g) (H2B/g) (Histone H2B.h) (H2B/h) (Histone H2B.k) (H2B/k) (Histone H2B.l) (H2B/l)
Gene: H2BC4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	25281560
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 560 Hs			1 126
+	Hs
		123255 CBX4_HUMAN (1-560): 7.58e-163: 477: 100.00		H2B2E_HUMAN (1-126): 5.61e-54: 166: 99.21
+	Hs
		123191 CBX4_HUMAN (1-560): 7.58e-163: 477: 100.00		H2B1B_HUMAN (1-126): 1.52e-53: 165: 97.62
+	Hs
		1087361 MPP8_HUMAN (6-431): 5.25e-87: 289: 13.72		H2B2E_HUMAN (1-126): 5.61e-54: 166: 99.21
+	Hs
		918634 MPP8_HUMAN (6-431): 5.25e-87: 289: 13.72		H2B1C_HUMAN (1-126): 1.05e-53: 166: 100.00
+	Hs
		1059155 CBX2_HUMAN (2-559): 1.19e-82: 269: 23.54		H2B2E_HUMAN (1-126): 5.61e-54: 166: 99.21
+	Hs
		918366 CBX2_HUMAN (2-559): 1.19e-82: 269: 23.54		H2B1C_HUMAN (1-126): 1.05e-53: 166: 100.00
+	Hs
		707633 CBX2_HUMAN (2-559): 1.19e-82: 269: 23.54		H2B1B_HUMAN (1-126): 1.52e-53: 165: 97.62
+	Hs
		316041 CBX6_HUMAN (1-419): 4.68e-61: 209: 24.19		H2B2E_HUMAN (1-126): 5.61e-54: 166: 99.21
+	Hs
		315974 CBX6_HUMAN (1-419): 4.68e-61: 209: 24.19		H2B1B_HUMAN (1-126): 1.52e-53: 165: 97.62
+	Hs
		1087494 CDYL_HUMAN (2-288): 4.47e-50: 183: 16.35		H2B2E_HUMAN (1-126): 5.61e-54: 166: 99.21
+	Hs
		918778 CDYL_HUMAN (2-288): 4.47e-50: 183: 16.35		H2B1C_HUMAN (1-126): 1.05e-53: 166: 100.00
+	Hs
		1231263 CDYL_HUMAN (2-288): 4.47e-50: 183: 16.35		H2B3B_HUMAN (1-126): 8.29e-52: 161: 95.24
+	Hs
		1282983 CDYL_HUMAN (2-288): 4.47e-50: 183: 16.35		H2B1A_HUMAN (1-126): 3.14e-46: 147: 84.25
+	Hs
		1027018 CBX3_HUMAN (9-163): 8.8e-44: 155: 21.94		H2B2E_HUMAN (1-126): 5.61e-54: 166: 99.21
+	Hs
		241519 CBX3_HUMAN (9-163): 8.8e-44: 155: 21.94		H2B1K_HUMAN (1-126): 1.3e-53: 166: 99.21
+	Hs
		420833 CBX3_HUMAN (9-163): 8.8e-44: 155: 21.94		H2B1J_HUMAN (1-126): 6.62e-54: 166: 98.41
+	Hs
		918334 CBX3_HUMAN (9-163): 8.8e-44: 155: 21.94		H2B1C_HUMAN (1-126): 1.05e-53: 166: 100.00
+	Mm
		1145436 Q9DCC5_MOUSE (9-163): 8.8e-44: 155: 21.94		H2B1B_MOUSE (1-126): 4.59e-52: 162: 96.83
+	Hs
		241469 CBX5_HUMAN (11-171): 7.04e-41: 148: 19.88		H2B1K_HUMAN (1-126): 1.3e-53: 166: 99.21
+	Mm
		1143022 CBX5_MOUSE (11-169): 3.2e-41: 149: 20.71		H2B1B_MOUSE (1-126): 4.59e-52: 162: 96.83