Protein: TRI39
E3 ubiquitin-protein ligase TRIM39 (EC 2.3.2.27) (RING finger protein 23) (RING-type E3 ubiquitin transferase TRIM39) (Testis-abundant finger protein) (Tripartite motif-containing protein 39)

Gene: TRI39, TRIM39
Organism: Homo sapiens
Interactions: 122
UniProt ID: Q9HCM9

Gene Ontology (top 5):
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005739 - mitochondrion
GO:0005829 - cytosol
GO:0006915 - apoptotic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1439319

TRI39
E3 ubiquitin-protein ligase TRIM39

7

17

Small-scale

0.974

High

1439329

TRI17
E3 ubiquitin-protein ligase TRIM17

5

16

High-throughput

0.940

High

623551

RO52
E3 ubiquitin-protein ligase TRIM21

4

18

High-throughput

0.911

High

1348519

LNX1
E3 ubiquitin-protein ligase LNX

3

8

High-throughput

0.871

High

1124308

IF4A2
Eukaryotic initiation factor 4A-II

2

6

High-throughput

0.811

High

906790

UB2D1
Ubiquitin-conjugating enzyme E2 D1

8

20

Small-scale

0.755

High

957208

UB2D3
Ubiquitin-conjugating enzyme E2 D3

6

20

High-throughput

0.739

High

1397295

UB2E2
Ubiquitin-conjugating enzyme E2 E2

6

20

High-throughput

0.738

High

1439327

UB2D4
Ubiquitin-conjugating enzyme E2 D4

5

20

High-throughput

0.726

High

1381205

UB2E3
Ubiquitin-conjugating enzyme E2 E3

5

20

High-throughput

0.722

High

957675

UBE2K
Ubiquitin-conjugating enzyme E2 K

5

20

High-throughput

0.721

High

1382344

RN166
E3 ubiquitin-protein ligase RNF166

1

18

High-throughput

0.698

High

1420186

TRIM8
E3 ubiquitin-protein ligase TRIM8

1

19

High-throughput

0.698

High

215191

PRPF3
U4/U6 small nuclear ribonucleoprotein Prp3

5

0

High-throughput

0.697

High

1391959

DCNL1
DCN1-like protein 1

5

0

High-throughput

0.697

High

982330

UB2D2
Ubiquitin-conjugating enzyme E2 D2

4

20

High-throughput

0.696

High

1420225

UBXN6
UBX domain-containing protein 6

5

0

High-throughput

0.686

High

181827

EPHB6
Ephrin type-B receptor 6

3

3

High-throughput

0.675

High

954915

PSA6
Proteasome subunit alpha type-6

3

4

High-throughput

0.675

High

1414144

MED18
Mediator of RNA polymerase II transcription subunit 18

4

0

High-throughput

0.670

High

600073

ZNF19
Zinc finger protein 19

3

19

High-throughput

0.667

High

1250413

ZN562
Zinc finger protein 562

3

20

High-throughput

0.667

High

1254177

ZN621
Zinc finger protein 621

3

20

High-throughput

0.667

High

1385468

ZN707
Zinc finger protein 707

3

20

High-throughput

0.667

High

1392748

ZN764
Zinc finger protein 764

3

20

High-throughput

0.662

High

1393363

ZN419
Zinc finger protein 419

3

20

High-throughput

0.657

High

246967

KDM1A
Lysine-specific histone demethylase 1A

3

3

High-throughput

0.649

High

1437499

UBTD1
Ubiquitin domain-containing protein 1

4

3

High-throughput

0.644

High

1316774

WDFY3
WD repeat and FYVE domain-containing protein 3

2

2

High-throughput

0.640

High

212820

ZN264
Zinc finger protein 264

2

15

High-throughput

0.628

High

1205676

ZN311
Zinc finger protein 311

2

8

High-throughput

0.628

High

1230905

Z324B
Zinc finger protein 324B

2

19

High-throughput

0.628

High

1294608

Z354C
Zinc finger protein 354C

2

16

High-throughput

0.628

High

1385018

ZN669
Zinc finger protein 669

2

20

High-throughput

0.628

High

1416284

ZN416
Zinc finger protein 416

2

19

High-throughput

0.628

High

1437553

ZN556
Zinc finger protein 556

2

14

High-throughput

0.628

High

1439320

ZN331
Zinc finger protein 331

2

13

High-throughput

0.628

High

1439321

ZIM2
Zinc finger imprinted 2

2

19

High-throughput

0.628

High

1439323

ZN223
Zinc finger protein 223

2

17

High-throughput

0.628

High

1439325

ZN490
Zinc finger protein 490

2

15

High-throughput

0.628

High

600471

ZNF26
Zinc finger protein 26

2

12

High-throughput

0.628

High

666913

CCNC
Cyclin-C

2

2

High-throughput

0.628

High

909393

UB2E1
Ubiquitin-conjugating enzyme E2 E1

2

20

High-throughput

0.619

High

1357058

UBTD2
Ubiquitin domain-containing protein 2

2

3

High-throughput

0.613

High

128479

PSMD9
26S proteasome non-ATPase regulatory subunit 9

2

0

High-throughput

0.613

High

1411082

PLCD4
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4

2

1

High-throughput

0.608

High

320779

UBXN7
UBX domain-containing protein 7

2

3

High-throughput

0.606

High

633798

PSB1
Proteasome subunit beta type-1

2

4

High-throughput

0.606

High

931604

RD23A
UV excision repair protein RAD23 homolog A

2

13

High-throughput

0.606

High

1325120

MTURN
Maturin

2

2

High-throughput

0.606

High

1420017

UBL5
Ubiquitin-like protein 5

2

1

High-throughput

0.606

High

601982

ZNF8
Zinc finger protein 8

2

20

High-throughput

0.601

High

1125964

GAMT
Guanidinoacetate N-methyltransferase

2

0

High-throughput

0.580

High

1357092

CATIN
Splicing factor Cactin

1

1

Small-scale

0.573

High

1046423

UBXN1
UBX domain-containing protein 1

1

7

High-throughput

0.573

High

1130721

DIP2A
Disco-interacting protein 2 homolog A

1

3

High-throughput

0.573

High

1380359

ZKSC4
Zinc finger protein with KRAB and SCAN domains 4

1

18

High-throughput

0.573

High

1412788

UBAC1
Ubiquitin-associated domain-containing protein 1

1

5

High-throughput

0.573

High

414669

P53
Cellular tumor antigen p53

1

6

Small-scale

0.561

High

1412189

LXN
Latexin

1

0

High-throughput

0.549

High

908789

MAT1
CDK-activating kinase assembly factor MAT1

1

6

High-throughput

0.541

High

996025

UB2L3
Ubiquitin-conjugating enzyme E2 L3

1

20

High-throughput

0.541

High

1103941

UB2V1
Ubiquitin-conjugating enzyme E2 variant 1

1

20

High-throughput

0.541

High

1383936

UBE2W
Ubiquitin-conjugating enzyme E2 W

1

20

High-throughput

0.541

High

1393041

PDLI5
PDZ and LIM domain protein 5

1

6

High-throughput

0.541

High

67049

ZN726
Zinc finger protein 726

1

5

High-throughput

0.536

High

600033

ZNF17
Zinc finger protein 17

1

12

High-throughput

0.536

High

833782

KDM5C
Lysine-specific demethylase 5C

1

5

High-throughput

0.536

High

902989

ZNF81
Zinc finger protein 81

1

6

High-throughput

0.536

High

1066108

ZN543
Zinc finger protein 543

1

16

High-throughput

0.536

High

1081806

ZN816
Zinc finger protein 816

1

6

High-throughput

0.536

High

1128687

ZN460
Zinc finger protein 460

1

19

High-throughput

0.536

High

1187617

ZN718
Zinc finger protein 718

1

11

High-throughput

0.536

High

1207352

ZN484
Zinc finger protein 484

1

7

High-throughput

0.536

High

1216649

ZN658
Zinc finger protein 658

1

5

High-throughput

0.536

High

1228863

ZN776
Zinc finger protein 776

1

20

High-throughput

0.536

High

1245592

ZN773
Zinc finger protein 773

1

20

High-throughput

0.536

High

1253087

ZN620
Zinc finger protein 620

1

20

High-throughput

0.536

High

1332346

ZN383
Zinc finger protein 383

1

19

High-throughput

0.536

High

1336898

ZN248
Zinc finger protein 248

1

13

High-throughput

0.536

High

1386442

ZN689
Zinc finger protein 689

1

20

High-throughput

0.536

High

1395173

ZN333
Zinc finger protein 333

1

18

High-throughput

0.536

High

1439322

ZN112
Zinc finger protein 112

1

5

High-throughput

0.536

High

1439324

ZN214
Zinc finger protein 214

1

11

High-throughput

0.536

High

69448

A8K2R3
Lysine-specific histone demethylase 1A

1

3

High-throughput

0.515

High

1439328

RNF11
RING finger protein 11

1

4

High-throughput

0.515

High

1410423

HINFP
Histone H4 transcription factor

1

17

High-throughput

0.508

High

423227

A4
Amyloid-beta precursor protein

1

4

High-throughput

0.501

High

508670

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

10

High-throughput

0.501

High

957847

UBE2N
Ubiquitin-conjugating enzyme E2 N

1

20

High-throughput

0.501

High

288516

UBP2
Ubiquitin carboxyl-terminal hydrolase 2

1

17

High-throughput

0.481

High

386260

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

17

High-throughput

0.481

High

853528

UBP5
Ubiquitin carboxyl-terminal hydrolase 5

1

20

High-throughput

0.481

High

1199464

UBP39
Ubiquitin carboxyl-terminal hydrolase 39

1

20

High-throughput

0.481

High

1387340

OTUB2
Ubiquitin thioesterase OTUB2

1

4

High-throughput

0.481

High

362379

ABL1
Tyrosine-protein kinase ABL1

1

8

High-throughput

0.479

High

440739

FYN
Tyrosine-protein kinase Fyn

1

8

High-throughput

0.479

High

594108

NCK1
SH2/SH3 adapter protein NCK1

1

15

High-throughput

0.479

High

613190

EGR1
Early growth response protein 1

1

13

High-throughput

0.479

High

808176

CDN1A
Cyclin-dependent kinase inhibitor 1

1

3

Small-scale

0.479

High

853414

CBX5
Chromobox protein homolog 5

1

7

Small-scale

0.479

High

855762

CRK
Adapter molecule crk

1

11

High-throughput

0.479

High

894597

GDIB
Rab GDP dissociation inhibitor beta

1

1

Small-scale

0.479

High

901588

RAB7A
Ras-related protein Rab-7a

1

5

Small-scale

0.479

High

987957

GRB2
Growth factor receptor-bound protein 2

1

14

High-throughput

0.479

High

1014208

CBX1
Chromobox protein homolog 1

1

7

Small-scale

0.479

High

1097578

CBX3
Chromobox protein homolog 3

1

7

Small-scale

0.479

High

1140895

KIF14
Kinesin-like protein KIF14

1

16

High-throughput

0.479

High

1385143

MOAP1
Modulator of apoptosis 1

1

3

Small-scale

0.479

High

73640

B2R886
Dendritic cell-derived ubiquitin-like protein, isoform CRA_a

1

3

High-throughput

0.470

High

1243361

Q6P9E2
RECK protein

1

3

High-throughput

0.470

High

1291804

MON1A
Vacuolar fusion protein MON1 homolog A

1

0

Small-scale

0.458

High

1420643

DCLK3
Serine/threonine-protein kinase DCLK3

1

7

Small-scale

0.457

High

69832

ZN785
Zinc finger protein 785

1

20

High-throughput

0.445

High

352042

RECK
Reversion-inducing cysteine-rich protein with Kazal motifs

1

3

High-throughput

0.439

High

1273065

OTU6A
OTU domain-containing protein 6A

1

3

High-throughput

0.439

High

87569

SEHBP
Transcriptional regulator SEHBP

1

0

High-throughput

0.426

High

75539

B3KSH4
Huntingtin interacting protein 2, isoform CRA_a

1

20

High-throughput

0.417

High

1439326

POLI
DNA polymerase iota

2

0

High-throughput

0.334

High

60652

SMCO3
Single-pass membrane and coiled-coil domain-containing protein 3

1

0

High-throughput

0.299

High

1205360

TTC32
Tetratricopeptide repeat protein 32

1

0

High-throughput

0.299

High


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Last updated: 11Aug2025