HitPredict

Interactor 1: CBX4 (O00257)
E3 SUMO-protein ligase CBX4 (EC 2.3.2.-) (Chromobox protein homolog 4) (Polycomb 2 homolog) (Pc2) (hPc2)
Gene: CBX4

Interactor 2: H11 (Q02539)
Histone H1.1 (Histone H1a)
Gene: H1-1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	21282530
Identification Methods	tandem affinity purification
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 560 Hs			1 215
+	Hs
		315962 CBX6_HUMAN (1-419): 4.68e-61: 209: 24.19		H12_HUMAN (32-175): 4.83e-23: 94: 54.86
+	Hs
		315961 CBX6_HUMAN (1-419): 4.68e-61: 209: 24.19		H15_HUMAN (1-118): 1.18e-22: 93.2: 72.88
+	Hs
		315955 CBX6_HUMAN (1-419): 4.68e-61: 209: 24.19		H14_HUMAN (1-149): 9.6e-22: 90.5: 63.76
+	Hs
		316015 CBX6_HUMAN (1-419): 4.68e-61: 209: 24.19		H11_HUMAN (1-199): 7.29e-21: 88.2: 100.00
+	Mm
		794637 Q9DCC5_MOUSE (9-163): 8.8e-44: 155: 21.94		H14_MOUSE (1-200): 3.73e-24: 97.1: 57.01
+	Mm
		794626 CBX5_MOUSE (11-169): 3.2e-41: 149: 20.71		H14_MOUSE (1-200): 3.73e-24: 97.1: 57.01
+	Hs
		489023 CBX3_HUMAN (9-163): 8.8e-44: 155: 21.94		H14_HUMAN (1-149): 9.6e-22: 90.5: 63.76
+	Hs
		559009 CBX5_HUMAN (11-171): 7.04e-41: 148: 19.88		H15_HUMAN (1-118): 1.18e-22: 93.2: 72.88
+	Mm
		794619 CBX1_MOUSE (17-163): 1.89e-39: 144: 21.05		H14_MOUSE (1-200): 3.73e-24: 97.1: 57.01
+	Hs
		488936 CBX5_HUMAN (11-171): 7.04e-41: 148: 19.88		H14_HUMAN (1-149): 9.6e-22: 90.5: 63.76
+	Mm
		794648 CBX5_MOUSE (11-169): 3.2e-41: 149: 20.71		H11_MOUSE (1-124): 1.61e-17: 79.4: 79.84
+	Hs
		559255 CBX8_HUMAN (1-259): 7.16e-33: 131: 28.22		H15_HUMAN (1-118): 1.18e-22: 93.2: 72.88
+	Hs
		489290 CBX8_HUMAN (1-259): 7.16e-33: 131: 28.22		H14_HUMAN (1-149): 9.6e-22: 90.5: 63.76