Protein: PDLI1
PDZ and LIM domain protein 1 (C-terminal LIM domain protein 1) (Elfin) (LIM domain protein CLP-36)

Gene: PDLI1, PDLIM1
Organism: Homo sapiens
Interactions: 93
UniProt ID: O00151

Gene Ontology (top 5):
GO:0001666 - response to hypoxia
GO:0001725 - stress fiber
GO:0003713 - transcription coactivator activity
GO:0003779 - actin binding
GO:0005667 - transcription regulator complex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

123201

ACTN4
Alpha-actinin-4

7

20

Small-scale

0.971

High

123214

ACTN1
Alpha-actinin-1

5

20

Small-scale

0.937

High

123228

ACTN2
Alpha-actinin-2

4

20

Small-scale

0.897

High

123242

ACTN3
Alpha-actinin-3

3

20

High-throughput

0.861

High

123276

NUD12
NAD-capped RNA hydrolase NUDT12

3

18

High-throughput

0.861

High

123287

LIMA1
LIM domain and actin-binding protein 1

1

13

High-throughput

0.691

High

123218

GFAP
Glial fibrillary acidic protein

3

17

High-throughput

0.666

High

123231

RANG
Ran-specific GTPase-activating protein

2

2

High-throughput

0.628

High

123233

SOX2
Transcription factor SOX-2

2

2

High-throughput

0.628

High

123236

RB27A
Ras-related protein Rab-27A

1

5

High-throughput

0.618

High

123198

PDLI1
PDZ and LIM domain protein 1

1

15

Small-scale

0.618

High

123208

MYC
Myc proto-oncogene protein

1

8

High-throughput

0.618

High

123202

PRKN
E3 ubiquitin-protein ligase parkin

2

7

High-throughput

0.584

High

123232

YAP1
Transcriptional coactivator YAP1

2

20

Small-scale

0.584

High

123212

VIME
Vimentin

1

18

High-throughput

0.541

High

123241

HXC5
Homeobox protein Hox-C5

1

5

High-throughput

0.536

High

123268

STK35
Serine/threonine-protein kinase 35

1

20

Small-scale

0.527

High

123221

IL7RA
Interleukin-7 receptor subunit alpha

1

0

High-throughput

0.517

High

123210

APOD
Apolipoprotein D

1

0

High-throughput

0.513

High

123253

FBX31
F-box only protein 31

1

0

High-throughput

0.513

High

123211

TNR16
Tumor necrosis factor receptor superfamily member 16

1

1

Small-scale

0.512

High

123206

KS6A5
Ribosomal protein S6 kinase alpha-5

1

7

High-throughput

0.508

High

123250

MK06
Mitogen-activated protein kinase 6

1

8

High-throughput

0.508

High

123227

PE2R4
Prostaglandin E2 receptor EP4 subtype

1

20

High-throughput

0.494

High

123284

B3GN2
N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 2

1

1

High-throughput

0.489

High

123209

ESR1
Estrogen receptor

1

15

Small-scale

0.479

High

123215

CADH1
Cadherin-1

1

6

High-throughput

0.479

High

123216

XRCC6
X-ray repair cross-complementing protein 6

1

1

High-throughput

0.479

High

123219

EZRI
Ezrin

1

8

High-throughput

0.479

High

123222

RO52
E3 ubiquitin-protein ligase TRIM21

1

2

High-throughput

0.479

High

123229

SYUA
Alpha-synuclein

1

6

Small-scale

0.479

High

123230

CCNF
Cyclin-F

1

3

High-throughput

0.479

High

123235

GSK3B
Glycogen synthase kinase-3 beta

1

3

High-throughput

0.479

High

123237

FOXA1
Hepatocyte nuclear factor 3-alpha

1

1

High-throughput

0.479

High

123243

UBP4
Ubiquitin carboxyl-terminal hydrolase 4

1

4

High-throughput

0.479

High

123245

G3BP1
Ras GTPase-activating protein-binding protein 1

1

2

High-throughput

0.479

High

123246

CUL3
Cullin-3

1

8

High-throughput

0.479

High

123252

RN123
E3 ubiquitin-protein ligase RNF123

1

7

High-throughput

0.479

High

123254

DCA15
DDB1- and CUL4-associated factor 15

1

1

High-throughput

0.479

High

123262

GOLI
E3 ubiquitin-protein ligase RNF130

1

4

High-throughput

0.479

High

123266

RN149
E3 ubiquitin-protein ligase RNF149

1

3

High-throughput

0.479

High

123267

BICD2
Protein bicaudal D homolog 2

1

19

High-throughput

0.479

High

123272

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

2

High-throughput

0.479

High

123273

FBX32
F-box only protein 32

1

2

High-throughput

0.479

High

123278

PKHA4
Pleckstrin homology domain-containing family A member 4

1

20

High-throughput

0.479

High

123285

LUZP4
Leucine zipper protein 4

1

1

Small-scale

0.479

High

123286

ZRAN1
Ubiquitin thioesterase ZRANB1

1

8

High-throughput

0.479

High

123288

XPO7
Exportin-7

1

13

High-throughput

0.479

High

123247

HNRPD
Heterogeneous nuclear ribonucleoprotein D0

1

4

High-throughput

0.470

High

123213

IMDH2
Inosine-5'-monophosphate dehydrogenase 2

1

0

High-throughput

0.458

High

123248

CUL7
Cullin-7

1

0

High-throughput

0.458

High

123258

RICTR
Rapamycin-insensitive companion of mTOR

1

0

High-throughput

0.458

High

123270

HASP
Serine/threonine-protein kinase haspin

1

0

High-throughput

0.458

High

123281

MOG1
Ran guanine nucleotide release factor

1

0

High-throughput

0.458

High

123277

MLP3C
Microtubule-associated protein 1 light chain 3 gamma

1

3

High-throughput

0.457

High

123204

NSMA
Sphingomyelin phosphodiesterase 2

1

1

High-throughput

0.445

High

123217

CFTR
Cystic fibrosis transmembrane conductance regulator

1

6

High-throughput

0.445

High

123199

RN103
E3 ubiquitin-protein ligase RNF103

1

2

High-throughput

0.437

High

123200

TGON2
Trans-Golgi network integral membrane protein 2

1

10

High-throughput

0.437

High

123220

RFA2
Replication protein A 32 kDa subunit

1

2

High-throughput

0.437

High

123223

KCNA3
Potassium voltage-gated channel subfamily A member 3

1

19

High-throughput

0.437

High

123224

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

1

High-throughput

0.437

High

123225

CALX
Calnexin

1

1

High-throughput

0.437

High

123244

RFA4
Replication protein A 30 kDa subunit

1

2

High-throughput

0.437

High

123249

EEA1
Early endosome antigen 1

1

11

High-throughput

0.437

High

123256

SCYL2
SCY1-like protein 2

1

10

High-throughput

0.437

High

123257

RHDF2
Inactive rhomboid protein 2

1

4

High-throughput

0.437

High

123260

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

2

High-throughput

0.437

High

123261

NAA40
N-alpha-acetyltransferase 40

1

3

High-throughput

0.437

High

123269

RHBL4
Rhomboid-related protein 4

1

4

High-throughput

0.437

High

123274

CHM4C
Charged multivesicular body protein 4c

1

1

High-throughput

0.437

High

123275

SNR40
U5 small nuclear ribonucleoprotein 40 kDa protein

1

6

High-throughput

0.437

High

123279

GORS2
Golgi reassembly-stacking protein 2

1

2

High-throughput

0.437

High

123280

NMRL1
NmrA-like family domain-containing protein 1

1

1

High-throughput

0.437

High

123282

CYLD
Ubiquitin carboxyl-terminal hydrolase CYLD

1

4

Small-scale

0.437

High

123283

RNF12
E3 ubiquitin-protein ligase RLIM

1

3

Small-scale

0.437

High

123239

GBRL2
Gamma-aminobutyric acid receptor-associated protein-like 2

1

3

High-throughput

0.408

High

123205

ECI2
Enoyl-CoA delta isomerase 2

1

2

High-throughput

0.407

High

123207

DYR
Dihydrofolate reductase

1

1

High-throughput

0.407

High

123255

PKHA7
Pleckstrin homology domain-containing family A member 7

1

20

High-throughput

0.407

High

123234

INAR2
Interferon alpha/beta receptor 2

1

0

High-throughput

0.279

Low

123263

SGPP2
Sphingosine-1-phosphate phosphatase 2

1

0

High-throughput

0.279

Low

123265

HORM2
HORMA domain-containing protein 2

1

0

High-throughput

0.279

Low

123271

SRALN
Sarcoplasmic/endoplasmic reticulum calcium ATPase regulator ARLN

1

0

High-throughput

0.279

Low

123289

RM42
Large ribosomal subunit protein mL42

1

0

High-throughput

0.279

Low

123240

SPT4H
Transcription elongation factor SPT4

1

0

High-throughput

0.265

Low

123203

EIF1B
Eukaryotic translation initiation factor 1b

1

0

High-throughput

0.249

Low

123226

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.249

Low

123238

BID
BH3-interacting domain death agonist

1

0

Small-scale

0.249

Low

123264

EMC5
ER membrane protein complex subunit 5

1

0

High-throughput

0.249

Low

123251

PGPS1
CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase, mitochondrial

1

0

High-throughput

0.238

Low

123259

Q75KN0
Uncharacterized protein FLJ10842

1

0

High-throughput

0.238

Low


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Last updated: 11Aug2025