HitPredict

Interactor 1: CBX4 (O00257)
E3 SUMO-protein ligase CBX4 (EC 2.3.2.-) (Chromobox protein homolog 4) (Polycomb 2 homolog) (Pc2) (hPc2)
Gene: CBX4

Interactor 2: SLX4 (Q8IY92)
Structure-specific endonuclease subunit SLX4 (BTB/POZ domain-containing protein 12)
Gene: SLX4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	37071664, 37059091
Identification Methods	proximity labelling technology, affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 560 Hs			1 1834
+	Hs
		1027113 CBX3_HUMAN (9-163): 8.8e-44: 155: 21.94		SLX4_HUMAN (1-1834): 0: 1486: 100.00
+	Hs
		123199 CBX4_HUMAN (1-560): 7.58e-163: 477: 100.00		KI67_HUMAN (889-1833): 3.44e-23: 110: 10.79
+	Hs
		123298 CBX4_HUMAN (1-560): 7.58e-163: 477: 100.00		CBP_HUMAN (885-1778): 4.86e-09: 64: 9.57
+	Hs
		1056829 CBX2_HUMAN (2-559): 1.19e-82: 269: 23.54		MDC1_HUMAN (801-1763): 7.3e-12: 73.2: 9.54
+	Hs
		801113 CBX3_HUMAN (9-163): 8.8e-44: 155: 21.94		KI67_HUMAN (889-1833): 3.44e-23: 110: 10.79
+	Hs
		801081 CBX1_HUMAN (17-163): 1.89e-39: 144: 21.05		KI67_HUMAN (889-1833): 3.44e-23: 110: 10.79
+	Hs
		1026998 CBX3_HUMAN (9-163): 8.8e-44: 155: 21.94		MDC1_HUMAN (801-1763): 7.3e-12: 73.2: 9.54
+	Hs
		203821 SUV91_HUMAN (4-154): 1.01e-32: 131: 21.15		CABIN_HUMAN (880-1364): 9.59e-09: 63.1: 13.91