HitPredict

Interactor 1: LZTR1 (Q8N653)
Leucine-zipper-like transcriptional regulator 1 (LZTR-1)
Gene: LZTR1

Interactor 2: RIT2 (Q99578)
GTP-binding protein Rit2 (EC 3.6.5.2) (Ras-like protein expressed in neurons) (Ras-like without CAAX protein 2)
Gene: RIT2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.73	0.60	0.662

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005794 - Golgi apparatus
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 840 Hs			1 217
+	Hs
		1235444 LZTR1_HUMAN (1-840): 0: 613: 100.00		RIT1_HUMAN (1-217): 2.19e-80: 240: 66.21
+	Hs
		156098 LZTR1_HUMAN (1-840): 0: 613: 100.00		RASM_HUMAN (21-184): 7.76e-48: 157: 52.41
+	Hs
		348788 LZTR1_HUMAN (1-840): 0: 613: 100.00		RASN_HUMAN (20-183): 1.37e-46: 154: 52.44
+	Hs
		349482 LZTR1_HUMAN (1-840): 0: 613: 100.00		RASH_HUMAN (20-185): 5e-46: 152: 50.60
+	Hs
		350348 LZTR1_HUMAN (1-840): 0: 613: 100.00		RASK_HUMAN (20-183): 3.49e-46: 152: 52.44
+	Hs
		214190 SPOP_HUMAN (662-837): 6.69e-62: 215: 31.29		RAB1A_HUMAN (10-205): 9.36e-82: 243: 25.89
+	Hs
		214018 SPOP_HUMAN (662-837): 6.69e-62: 215: 31.29		RASH_HUMAN (20-185): 5e-46: 152: 50.60
+	Hs
		1120795 KLH12_HUMAN (1-186): 2.59e-28: 122: 18.82		RIT1_HUMAN (1-217): 2.19e-80: 240: 66.21
+	Hs
		349705 KLHL3_HUMAN (324-575): 1.65e-09: 63.4: 10.67		RASH_HUMAN (20-185): 5e-46: 152: 50.60