Protein: SRBD1
S1 RNA-binding domain-containing protein 1

Gene: SRBD1
Organism: Homo sapiens
Interactions: 121
UniProt ID: Q8N5C6

Gene Ontology (top 5):
GO:0003729 - mRNA binding
GO:0003735 - structural constituent of ribosome
GO:0006139 - nucleobase-containing compound metabolic process
GO:0006412 - translation

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

873478

PP2BC
Serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform

2

3

High-throughput

0.726

High

891247

GSK3A
Glycogen synthase kinase-3 alpha

2

3

High-throughput

0.726

High

436703

KPCB
Protein kinase C beta type

2

1

High-throughput

0.659

High

904929

MECP2
Methyl-CpG-binding protein 2

2

2

High-throughput

0.628

High

1037557

RL18A
Large ribosomal subunit protein eL20

2

3

High-throughput

0.628

High

997857

CSK21
Casein kinase II subunit alpha

1

8

High-throughput

0.618

High

1327535

RL26L
Ribosomal protein uL24-like

1

2

High-throughput

0.618

High

658272

RS3
Small ribosomal subunit protein uS3

2

4

High-throughput

0.601

High

208311

RRP8
Ribosomal RNA-processing protein 8

2

2

High-throughput

0.574

High

1327537

ARI1
E3 ubiquitin-protein ligase ARIH1

2

1

High-throughput

0.574

High

880339

RL34
Large ribosomal subunit protein eL34

2

0

High-throughput

0.559

High

487531

PARP1
Poly [ADP-ribose] polymerase 1

2

5

High-throughput

0.558

High

157611

CTRO
Citron Rho-interacting kinase

1

4

High-throughput

0.553

High

1327523

LN28A
Protein lin-28 homolog A

2

8

High-throughput

0.552

High

191708

MAGB2
Melanoma-associated antigen B2

2

2

High-throughput

0.549

High

785293

RL4
Large ribosomal subunit protein uL4

1

2

High-throughput

0.536

High

859903

RL28
Large ribosomal subunit protein eL28

1

1

High-throughput

0.536

High

969975

RS16
Small ribosomal subunit protein uS9

1

2

High-throughput

0.536

High

973235

RS13
Small ribosomal subunit protein uS15

1

2

High-throughput

0.536

High

372574

MYC
Myc proto-oncogene protein

2

4

High-throughput

0.533

High

980927

H2B1C
Histone H2B type 1-C/E/F/G/I

2

5

High-throughput

0.533

High

998542

H31
Histone H3.1

2

11

High-throughput

0.533

High

396506

ESR1
Estrogen receptor

2

5

High-throughput

0.521

High

1327511

SH2D3
SH2 domain-containing protein 3C

2

1

High-throughput

0.521

High

858985

RL27A
Large ribosomal subunit protein uL15

1

0

High-throughput

0.513

High

180341

RPAC1
DNA-directed RNA polymerases I and III subunit RPAC1

1

3

High-throughput

0.489

High

338901

CBX6
Chromobox protein homolog 6

1

4

High-throughput

0.489

High

351396

CBX7
Chromobox protein homolog 7

1

4

High-throughput

0.489

High

502057

H2AZ
Histone H2A.Z

1

5

High-throughput

0.489

High

502434

H2A1
Histone H2A type 1

1

6

High-throughput

0.489

High

657266

KALM
Anosmin-1

1

1

High-throughput

0.489

High

718428

CD6
T-cell differentiation antigen CD6

1

1

High-throughput

0.489

High

911305

IMA5
Importin subunit alpha-5

1

1

High-throughput

0.489

High

1027588

HNRPU
Heterogeneous nuclear ribonucleoprotein U

1

1

High-throughput

0.489

High

1099434

SRSF6
Serine/arginine-rich splicing factor 6

1

7

High-throughput

0.489

High

1137107

SART3
Spliceosome associated factor 3, U4/U6 recycling protein

1

2

High-throughput

0.489

High

1163056

H2B2E
Histone H2B type 2-E

1

5

High-throughput

0.489

High

1194214

LARP7
La-related protein 7

1

4

High-throughput

0.489

High

1216678

CROCC
Rootletin

1

4

High-throughput

0.489

High

1258230

UBP45
Ubiquitin carboxyl-terminal hydrolase 45

1

1

High-throughput

0.489

High

1281418

ZN467
Zinc finger protein 467

1

1

High-throughput

0.489

High

1327527

ABC3C
DNA dC->dU-editing enzyme APOBEC-3C

1

1

High-throughput

0.489

High

1327534

ABT1
Activator of basal transcription 1

1

2

High-throughput

0.489

High

472887

RU17
U1 small nuclear ribonucleoprotein 70 kDa

1

1

High-throughput

0.479

High

1215709

RC3H1
Roquin-1

1

3

High-throughput

0.479

High

1327524

RC3H2
Roquin-2

1

6

High-throughput

0.479

High

573573

ENPL
Endoplasmin

1

4

High-throughput

0.470

High

1011661

RT35
Small ribosomal subunit protein mS35

1

0

High-throughput

0.460

High

1327526

4ET
Eukaryotic translation initiation factor 4E transporter

1

0

High-throughput

0.460

High

615867

RL17
Large ribosomal subunit protein uL22

1

3

High-throughput

0.445

High

686271

RL13
Large ribosomal subunit protein eL13

1

2

High-throughput

0.445

High

809724

RS19
Small ribosomal subunit protein eS19

1

2

High-throughput

0.445

High

810217

RL3
Large ribosomal subunit protein uL3

1

1

High-throughput

0.445

High

969306

RS8
Small ribosomal subunit protein eS8

1

1

High-throughput

0.445

High

129256

MEN1
Menin

1

1

High-throughput

0.437

High

132161

WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2

1

3

High-throughput

0.437

High

143119

NFIB
Nuclear factor 1 B-type

1

4

High-throughput

0.437

High

406387

MYCN
N-myc proto-oncogene protein

1

4

High-throughput

0.437

High

412255

NTRK1
High affinity nerve growth factor receptor

1

1

High-throughput

0.437

High

474125

NFIC
Nuclear factor 1 C-type

1

5

High-throughput

0.437

High

504925

H2AB2
Histone H2A-Bbd type 2/3

1

6

High-throughput

0.437

High

589155

RFA2
Replication protein A 32 kDa subunit

1

2

High-throughput

0.437

High

695938

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

2

High-throughput

0.437

High

768641

RFA3
Replication protein A 14 kDa subunit

1

2

High-throughput

0.437

High

799982

COIL
Coilin

1

2

High-throughput

0.437

High

883610

CENPA
Histone H3-like centromeric protein A

1

11

High-throughput

0.437

High

979985

H4
Histone H4

1

5

High-throughput

0.437

High

1017022

H33
Histone H3.3

1

11

High-throughput

0.437

High

1087869

NFIA
Nuclear factor 1 A-type

1

6

High-throughput

0.437

High

1096099

TADBP
TAR DNA-binding protein 43

1

1

High-throughput

0.437

High

1126125

GRM2
Metabotropic glutamate receptor 2

1

1

High-throughput

0.437

High

1133534

NFIX
Nuclear factor 1 X-type

1

6

High-throughput

0.437

High

1161539

IF16
Gamma-interferon-inducible protein 16

1

3

High-throughput

0.437

High

1254638

TRI67
Tripartite motif-containing protein 67

1

2

High-throughput

0.437

High

1276479

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

2

High-throughput

0.437

High

1327512

KAT6A
Histone acetyltransferase KAT6A

1

6

High-throughput

0.437

High

1327513

SNR40
U5 small nuclear ribonucleoprotein 40 kDa protein

1

4

High-throughput

0.437

High

1327515

DDRGK
DDRGK domain-containing protein 1

1

1

High-throughput

0.437

High

1327518

CIC
Protein capicua homolog

1

3

High-throughput

0.437

High

1327519

CEP89
Centrosomal protein of 89 kDa

1

3

High-throughput

0.437

High

1327520

ANM1
Protein arginine N-methyltransferase 1

1

1

High-throughput

0.437

High

1327522

PKHA4
Pleckstrin homology domain-containing family A member 4

1

3

High-throughput

0.437

High

1327525

ANLN
Anillin

1

1

High-throughput

0.437

High

1327529

HECW2
E3 ubiquitin-protein ligase HECW2

1

4

High-throughput

0.437

High

1327531

ZRAN1
Ubiquitin thioesterase ZRANB1

1

1

High-throughput

0.437

High

1327533

HECD1
E3 ubiquitin-protein ligase HECTD1

1

5

High-throughput

0.437

High

1327536

ZN330
Zinc finger protein 330

1

2

High-throughput

0.437

High

288701

NPM3
Nucleoplasmin-3

1

1

High-throughput

0.407

High

290632

SURF6
Surfeit locus protein 6

1

1

High-throughput

0.407

High

430130

JUN
Transcription factor Jun

1

1

High-throughput

0.407

High

649365

H1T
Histone H1t

1

4

High-throughput

0.407

High

1037268

H11
Histone H1.1

1

4

High-throughput

0.407

High

1063431

GOGA2
Golgin subfamily A member 2

1

3

High-throughput

0.407

High

1112085

KRR1
KRR1 small subunit processome component homolog

1

1

High-throughput

0.407

High

1253146

NBEL2
Neurobeachin-like protein 2

1

3

High-throughput

0.407

High

517671

ZBT48
Zinc finger and BTB domain-containing protein 48

2

0

High-throughput

0.328

High

923664

RCAN1
Calcipressin-1

2

0

High-throughput

0.328

High

989914

CANB1
Calcineurin subunit B type 1

2

0

High-throughput

0.328

High

1279140

RHG22
Rho GTPase-activating protein 22

2

0

High-throughput

0.328

High

1292319

ZC3C1
Zinc finger C3HC-type protein 1

2

0

High-throughput

0.328

High

1327514

TRI44
Tripartite motif-containing protein 44

2

0

High-throughput

0.328

High

1327528

TAP26
Thyroid transcription factor 1-associated protein 26

2

0

High-throughput

0.328

High

952602

MYL6
Myosin light polypeptide 6

1

0

High-throughput

0.279

Low

1009250

PRR3
Proline-rich protein 3

1

0

High-throughput

0.279

Low

1036669

APBA1
Amyloid-beta A4 precursor protein-binding family A member 1

1

0

High-throughput

0.279

Low

1306876

INLR1
Interferon lambda receptor 1

1

0

High-throughput

0.279

Low

1316255

PACE1
Protein-associating with the carboxyl-terminal domain of ezrin

1

0

High-throughput

0.279

Low

1327516

CC140
Coiled-coil domain-containing protein 140

1

0

High-throughput

0.279

Low

1327517

CC85A
Coiled-coil domain-containing protein 85A

1

0

High-throughput

0.279

Low

1327532

ZN777
Zinc finger protein 777

1

0

High-throughput

0.279

Low

156315

G3PT
Glyceraldehyde-3-phosphate dehydrogenase, testis-specific

1

0

High-throughput

0.269

Low

1327530

FXL17
F-box/LRR-repeat protein 17

1

0

Small-scale

0.251

Low

294013

CD123
Translation initiation factor eIF2 assembly protein

1

0

High-throughput

0.249

Low

319904

UFL1
E3 UFM1-protein ligase 1

1

0

High-throughput

0.249

Low

417577

RPN1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

1

0

High-throughput

0.249

Low

883283

UB2R1
Ubiquitin-conjugating enzyme E2 R1

1

0

High-throughput

0.249

Low

986564

PPIA
Peptidyl-prolyl cis-trans isomerase A

1

0

High-throughput

0.249

Low

1327521

DDA1
DET1- and DDB1-associated protein 1

1

0

High-throughput

0.249

Low

224903

BUD23
18S rRNA

1

0

High-throughput

0.232

Low

601767

HMGA1
High mobility group protein HMG-I/HMG-Y

1

0

High-throughput

0.232

Low

1315228

CA174
UPF0688 protein C1orf174

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025