HitPredict

Interactor 1: SIR6 (Q8N6T7)
NAD-dependent protein deacylase sirtuin-6 (EC 2.3.1.-) (NAD-dependent protein deacetylase sirtuin-6) (EC 2.3.1.286) (Protein mono-ADP-ribosyltransferase sirtuin-6) (EC 2.4.2.-) (Regulatory protein SIR2 homolog 6) (hSIRT6) (SIR2-like protein 6)
Gene: SIRT6

Interactor 2: KS6C1 (Q96S38)
Ribosomal protein S6 kinase delta-1 (S6K-delta-1) (EC 2.7.11.1) (52 kDa ribosomal protein S6 kinase) (Ribosomal S6 kinase-like protein with two PSK domains 118 kDa protein) (SPHK1-binding protein)
Gene: RPS6KC1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	34244565
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 355 Hs			1 1066
+	Hs
		681939 SIR6_HUMAN (1-355): 2.25e-166: 469: 100.00		AKT1_HUMAN (707-1065): 2.45e-123: 388: 19.42
+	Hs
		681976 SIR1_HUMAN (25-336): 3.35e-99: 311: 21.83		AKT1_HUMAN (707-1065): 2.45e-123: 388: 19.42
+	Hs
		681927 SIR2_HUMAN (31-318): 3.2e-102: 308: 22.12		AKT1_HUMAN (707-1065): 2.45e-123: 388: 19.42