HitPredict

Interactor 1: ARHGH (Q96PE2)
Rho guanine nucleotide exchange factor 17 (164 kDa Rho-specific guanine-nucleotide exchange factor) (p164-RhoGEF) (p164RhoGEF) (Tumor endothelial marker 4)
Gene: ARHGEF17

Interactor 2: WDR83 (Q9BRX9)
WD repeat domain-containing protein 83 (Mitogen-activated protein kinase organizer 1) (MAPK organizer 1)
Gene: WDR83

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.50	0.609

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 2063 Hs			1 315
+	Hs
		1273271 ARHG2_HUMAN (858-1740): 6.2e-104: 360: 14.74		WDR83_HUMAN (1-315): 2.96e-102: 303: 100.00
+	Hs
		1273255 ARHG2_HUMAN (858-1740): 6.2e-104: 360: 14.74		FBXW7_HUMAN (103-315): 7.36e-58: 199: 23.61
+	Hs
		903416 ARHG2_HUMAN (858-1740): 6.2e-104: 360: 14.74		WDR5_HUMAN (140-312): 2.71e-53: 178: 23.60
+	Hs
		1288351 ITSN2_HUMAN (684-1531): 1.73e-91: 333: 15.69		SNR40_HUMAN (101-312): 1.44e-55: 185: 18.47
+	Hs
		61736 A6H8W8_HUMAN (684-1531): 7.36e-91: 330: 15.69		SNR40_HUMAN (101-312): 1.44e-55: 185: 18.47
+	Hs
		164142 ARHGA_HUMAN (799-2021): 4.97e-75: 278: 12.40		FBXW7_HUMAN (103-315): 7.36e-58: 199: 23.61
+	Hs
		1288311 ECT2_HUMAN (984-1451): 4.6e-72: 263: 20.70		SNR40_HUMAN (101-312): 1.44e-55: 185: 18.47
+	Hs
		903526 ECT2_HUMAN (984-1451): 4.6e-72: 263: 20.70		WDR5_HUMAN (140-312): 2.71e-53: 178: 23.60
+	Hs
		1254029 PREX1_HUMAN (1039-1431): 1.2e-74: 278: 23.91		NLE1_HUMAN (184-315): 2.98e-35: 134: 22.54