HitPredict

Interactor 1: VA0D2 (Q8N8Y2)
V-type proton ATPase subunit d 2 (V-ATPase subunit d 2) (Vacuolar proton pump subunit d 2)
Gene: ATP6V0D2

Interactor 2: VPP2 (Q9Y487)
V-type proton ATPase 116 kDa subunit a 2 (V-ATPase 116 kDa subunit a 2) (Lysosomal H(+)-transporting ATPase V0 subunit a 2) (TJ6) (Vacuolar proton translocating ATPase 116 kDa subunit a isoform 2)
Gene: ATP6V0A2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.62 1.00 0.789

The method score is based on:

Property Details
Experiments 28514442, 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains V_ATPase_I~vATP-synt_AC39
Common GO terms GO:0005765 - lysosomal membrane
GO:0007035 - vacuolar acidification
GO:0010008 - endosome membrane
GO:0016241 - regulation of macroautophagy
GO:0016471 - vacuolar proton-transporting V-type ATPase complex
and 2 others

more...
Homologous interactions 12

Homologous interactions

Color coding for hit scores

1 350
Hs

1 856
+ Hs
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+ Mm
+ Dm
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+ Sc
+ Sc

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Last updated: 15 Jul 2024