Protein: LRC8D
Volume-regulated anion channel subunit LRRC8D (Leucine-rich repeat-containing protein 5) (Leucine-rich repeat-containing protein 8D) (HsLRRC8D)

Gene: LRC8D, LRRC8D
Organism: Homo sapiens
Interactions: 32
UniProt ID: Q7L1W4

Gene Ontology (top 5):
GO:0001678 - intracellular glucose homeostasis
GO:0005225 - volume-sensitive anion channel activity
GO:0005737 - cytoplasm
GO:0005789 - endoplasmic reticulum membrane
GO:0005886 - plasma membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1243371

LRC8B
Volume-regulated anion channel subunit LRRC8B

3

13

High-throughput

0.855

High

1271351

RXFP1
Relaxin receptor 1

1

20

High-throughput

0.691

High

1271343

LRC8D
Volume-regulated anion channel subunit LRRC8D

1

20

Small-scale

0.638

High

142137

NPT3
Sodium-dependent phosphate transport protein 3

2

1

High-throughput

0.628

High

855340

5HT3A
5-hydroxytryptamine receptor 3A

2

9

High-throughput

0.628

High

126666

RHOD
Rho-related GTP-binding protein RhoD

1

20

High-throughput

0.618

High

374707

RASH
GTPase HRas

1

17

High-throughput

0.618

High

962200

RHOA
Transforming protein RhoA

1

20

High-throughput

0.618

High

978110

RHOB
Rho-related GTP-binding protein RhoB

1

20

High-throughput

0.618

High

1271344

LRC8A
Volume-regulated anion channel subunit LRRC8A

1

20

Small-scale

0.618

High

422416

A4
Amyloid-beta precursor protein

2

3

High-throughput

0.602

High

248479

O10H2
Olfactory receptor 10H2

1

5

High-throughput

0.536

High

851153

ACHA4
Neuronal acetylcholine receptor subunit alpha-4

1

2

High-throughput

0.536

High

938581

PSA
Puromycin-sensitive aminopeptidase

1

4

High-throughput

0.536

High

1195440

NKAI1
Sodium/potassium-transporting ATPase subunit beta-1-interacting protein 1

1

2

High-throughput

0.536

High

1271346

SIDT2
SID1 transmembrane family member 2

1

3

High-throughput

0.536

High

1271349

SHAN3
SH3 and multiple ankyrin repeat domains protein 3

1

9

High-throughput

0.536

High

1271350

TTYH1
Protein tweety homolog 1

1

4

High-throughput

0.536

High

1271354

HCST
Hematopoietic cell signal transducer

1

3

High-throughput

0.536

High

351267

OR2H2
Olfactory receptor 2H2

1

0

High-throughput

0.513

High

1271352

EXOS4
Exosome complex component RRP41

1

0

High-throughput

0.486

High

218372

TGON2
Trans-Golgi network integral membrane protein 2

1

4

High-throughput

0.479

High

418227

RPN2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

1

1

High-throughput

0.479

High

1138341

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

3

High-throughput

0.479

High

1271345

CXD3
Gap junction delta-3 protein

1

6

High-throughput

0.479

High

1271353

OTULL
Inactive ubiquitin thioesterase OTULINL

1

3

High-throughput

0.479

High

417529

RPN1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

1

0

High-throughput

0.458

High

1271347

CTL5
Choline transporter-like protein 5

1

3

High-throughput

0.445

High

1271348

CTL1
Choline transporter-like protein 1

1

3

High-throughput

0.445

High

1271355

S22AE
Solute carrier family 22 member 14

1

2

High-throughput

0.445

High

1204367

SGO1
Shugoshin 1

1

0

Small-scale

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025