Interactor 1: SPC24 (Q8NBT2)
Kinetochore protein Spc24 (hSpc24)
Gene: SPC24

Interactor 2: SPC25 (Q9HBM1)
Kinetochore protein Spc25 (hSpc25)
Gene: SPC25

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.94 1.00 0.974

The method score is based on:

Property Details
Experiments 32296183, 33961781, 26186194, 26496610, 28514442, 24981860, 22371557, unassigned1304, 15961401
Identification Methods two hybrid, affinity chromatography technology, two hybrid prey pooling approach, two hybrid array, anti tag coimmunoprecipitation, validated two hybrid, pull down, molecular sieving
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Spc24~Spindle_Spc25
Common GO terms GO:0000776 - kinetochore
GO:0005829 - cytosol
GO:0007059 - chromosome segregation
GO:0007094 - mitotic spindle assembly checkpoint signaling
GO:0008608 - attachment of spindle microtubules to kinetochore
and 2 others

more...

Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 197
Hs

1 224
+ Xl
+ Gg

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024