Protein: DHX37
Probable ATP-dependent RNA helicase DHX37 (EC 3.6.4.13) (DEAH box protein 37)

Gene: DHX37
Organism: Homo sapiens
Interactions: 135
UniProt ID: Q8IY37

Gene Ontology (top 5):
GO:0000462 - maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0003723 - RNA binding
GO:0003724 - RNA helicase activity
GO:0004386 - helicase activity
GO:0005524 - ATP binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

372527

MYC
Myc proto-oncogene protein

4

14

High-throughput

0.676

High

1313934

DDX56
Probable ATP-dependent RNA helicase DDX56

1

16

High-throughput

0.665

High

1009246

PRR3
Proline-rich protein 3

3

4

High-throughput

0.643

High

1313919

UT14A
U3 small nucleolar RNA-associated protein 14 homolog A

2

3

High-throughput

0.628

High

1313929

4ET
Eukaryotic translation initiation factor 4E transporter

1

1

High-throughput

0.621

High

346050

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

20

High-throughput

0.618

High

1254559

TRI67
Tripartite motif-containing protein 67

1

13

High-throughput

0.618

High

140992

NOP56
Nucleolar protein 56

2

7

High-throughput

0.611

High

208306

RRP8
Ribosomal RNA-processing protein 8

2

2

High-throughput

0.601

High

290624

SURF6
Surfeit locus protein 6

2

4

High-throughput

0.601

High

338895

CBX6
Chromobox protein homolog 6

2

7

High-throughput

0.601

High

860833

RS10
Small ribosomal subunit protein eS10

2

5

High-throughput

0.601

High

979050

RS6
Small ribosomal subunit protein eS6

2

5

High-throughput

0.584

High

998525

H31
Histone H3.1

2

11

High-throughput

0.584

High

1313921

MK67I
MKI67 FHA domain-interacting nucleolar phosphoprotein

2

14

High-throughput

0.584

High

1313937

ZRAN1
Ubiquitin thioesterase ZRANB1

2

11

High-throughput

0.584

High

1313943

HECD1
E3 ubiquitin-protein ligase HECTD1

1

16

High-throughput

0.553

High

191703

MAGB2
Melanoma-associated antigen B2

2

8

High-throughput

0.549

High

927404

ATX1
Ataxin-1

1

2

High-throughput

0.541

High

428852

RLA0
Large ribosomal subunit protein uL10

1

6

High-throughput

0.536

High

447206

NPM
Nucleophosmin

1

9

High-throughput

0.536

High

521798

H14
Histone H1.4

1

20

High-throughput

0.536

High

586776

RS2
Small ribosomal subunit protein uS5

1

8

High-throughput

0.536

High

686261

RL13
Large ribosomal subunit protein eL13

1

4

High-throughput

0.536

High

969966

RS16
Small ribosomal subunit protein uS9

1

8

High-throughput

0.536

High

973497

RS11
Small ribosomal subunit protein uS17

1

6

High-throughput

0.536

High

1004363

NOP14
Nucleolar protein 14

1

2

High-throughput

0.536

High

1099153

SRSF5
Serine/arginine-rich splicing factor 5

1

20

High-throughput

0.536

High

1118913

BYST
Bystin

1

2

High-throughput

0.536

High

1179321

TSR1
Pre-rRNA-processing protein TSR1 homolog

1

2

High-throughput

0.536

High

1194207

LARP7
La-related protein 7

1

20

High-throughput

0.536

High

1260369

H1FNT
Testis-specific H1 histone

1

1

High-throughput

0.536

High

1313907

PSPC1
Paraspeckle component 1

1

20

High-throughput

0.536

High

1313910

NEIL1
Endonuclease 8-like 1

1

3

High-throughput

0.536

High

1313917

RBM4B
RNA-binding protein 4B

1

9

High-throughput

0.536

High

1313931

ABC3C
DNA dC->dU-editing enzyme APOBEC-3C

1

6

High-throughput

0.536

High

1313941

PURG
Purine-rich element-binding protein gamma

1

4

High-throughput

0.536

High

1313942

ZN346
Zinc finger protein 346

1

8

High-throughput

0.536

High

1313945

YBOX2
Y-box-binding protein 2

1

15

High-throughput

0.536

High

337366

PARN
Poly(A)-specific ribonuclease PARN

1

0

High-throughput

0.513

High

788707

SRP14
Signal recognition particle 14 kDa protein

1

0

High-throughput

0.513

High

1313932

SLX9
Ribosome biogenesis protein SLX9 homolog

1

0

High-throughput

0.513

High

1313938

KDM5B
Lysine-specific demethylase 5B

1

0

High-throughput

0.513

High

1313939

MD2L2
Mitotic spindle assembly checkpoint protein MAD2B

1

0

High-throughput

0.493

High

1127424

FGFP1
Fibroblast growth factor-binding protein 1

1

3

High-throughput

0.489

High

1219025

RSBN1
Lysine-specific demethylase 9

1

2

High-throughput

0.489

High

1313913

ZN668
Zinc finger protein 668

1

3

High-throughput

0.489

High

1151576

TRIP6
Thyroid receptor-interacting protein 6

1

1

High-throughput

0.481

High

129243

MEN1
Menin

1

5

High-throughput

0.479

High

190988

RPA34
DNA-directed RNA polymerase I subunit RPA34

1

5

High-throughput

0.479

High

226570

TLX2
T-cell leukemia homeobox protein 2

1

3

High-throughput

0.479

High

242232

PRKN
E3 ubiquitin-protein ligase parkin

1

16

High-throughput

0.479

High

401119

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

8

High-throughput

0.479

High

406370

MYCN
N-myc proto-oncogene protein

1

14

High-throughput

0.479

High

487511

PARP1
Poly [ADP-ribose] polymerase 1

1

12

High-throughput

0.479

High

550354

PABP1
Polyadenylate-binding protein 1

1

9

High-throughput

0.479

High

589114

RFA2
Replication protein A 32 kDa subunit

1

13

High-throughput

0.479

High

643925

FBRL
rRNA 2'-O-methyltransferase fibrillarin

1

5

High-throughput

0.479

High

695898

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

10

High-throughput

0.479

High

768607

RFA3
Replication protein A 14 kDa subunit

1

10

High-throughput

0.479

High

851610

GATA4
Transcription factor GATA-4

1

2

High-throughput

0.479

High

879259

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

5

High-throughput

0.479

High

883605

CENPA
Histone H3-like centromeric protein A

1

11

High-throughput

0.479

High

904917

MECP2
Methyl-CpG-binding protein 2

1

13

High-throughput

0.479

High

931962

EPHB4
Ephrin type-B receptor 4

1

4

High-throughput

0.479

High

937815

FOXA1
Hepatocyte nuclear factor 3-alpha

1

6

High-throughput

0.479

High

942737

BCAR1
Breast cancer anti-estrogen resistance protein 1

1

7

High-throughput

0.479

High

980913

H2B1C
Histone H2B type 1-C/E/F/G/I

1

5

High-throughput

0.479

High

982729

RS24
Small ribosomal subunit protein eS24

1

3

High-throughput

0.479

High

984190

GBB2
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2

1

8

High-throughput

0.479

High

984848

RL31
Large ribosomal subunit protein eL31

1

6

High-throughput

0.479

High

1017009

H33
Histone H3.3

1

11

High-throughput

0.479

High

1100105

TIF1B
Transcription intermediary factor 1-beta

1

16

High-throughput

0.479

High

1107007

BIRC3
Baculoviral IAP repeat-containing protein 3

1

9

High-throughput

0.479

High

1107903

SQSTM
Sequestosome-1

1

4

High-throughput

0.479

High

1137842

TNIP1
TNFAIP3-interacting protein 1

1

15

High-throughput

0.479

High

1140533

KIF14
Kinesin-like protein KIF14

1

5

High-throughput

0.479

High

1149926

TERF2
Telomeric repeat-binding factor 2

1

1

High-throughput

0.479

High

1161529

IF16
Gamma-interferon-inducible protein 16

1

14

High-throughput

0.479

High

1215702

RC3H1
Roquin-1

1

11

High-throughput

0.479

High

1216999

MEX3C
RNA-binding E3 ubiquitin-protein ligase MEX3C

1

15

Small-scale

0.479

High

1238434

ZN746
Zinc finger protein 746

1

5

High-throughput

0.479

High

1281554

SLN11
Schlafen family member 11

1

6

High-throughput

0.479

High

1287066

MOB3B
MOB kinase activator 3B

1

1

High-throughput

0.479

High

1313903

ZBTB2
Zinc finger and BTB domain-containing protein 2

1

7

High-throughput

0.479

High

1313906

NUDC2
NudC domain-containing protein 2

1

11

High-throughput

0.479

High

1313908

ESR2
Estrogen receptor beta

1

16

High-throughput

0.479

High

1313911

AURKB
Aurora kinase B

1

7

High-throughput

0.479

High

1313912

DDRGK
DDRGK domain-containing protein 1

1

7

High-throughput

0.479

High

1313914

CI072
Guanine nucleotide exchange factor C9orf72

1

5

High-throughput

0.479

High

1313915

CIC
Protein capicua homolog

1

13

High-throughput

0.479

High

1313922

YTHD1
YTH domain-containing family protein 1

1

6

High-throughput

0.479

High

1313923

SPRTN
DNA-dependent metalloprotease SPRTN

1

1

High-throughput

0.479

High

1313925

PKHA4
Pleckstrin homology domain-containing family A member 4

1

10

High-throughput

0.479

High

1313926

RC3H2
Roquin-2

1

14

High-throughput

0.479

High

1313927

BRD7
Bromodomain-containing protein 7

1

17

High-throughput

0.479

High

1313928

ANLN
Anillin

1

6

High-throughput

0.479

High

1313930

SIR7
NAD-dependent protein deacetylase sirtuin-7

1

11

High-throughput

0.479

High

1313933

AKIP
Small ribosomal subunit protein mS38

1

1

High-throughput

0.479

High

1313935

UBP36
Ubiquitin carboxyl-terminal hydrolase 36

1

9

High-throughput

0.479

High

1313940

HOOK1
Protein Hook homolog 1

1

1

High-throughput

0.479

High

1313944

FZR1
Fizzy-related protein homolog

1

19

High-throughput

0.479

High

1313946

ZN330
Zinc finger protein 330

1

2

High-throughput

0.479

High

1313947

TRRAP
Transformation/transcription domain-associated protein

1

2

High-throughput

0.479

High

1313948

YTHD2
YTH domain-containing family protein 2

1

6

High-throughput

0.479

High

1313936

RGS17
Regulator of G-protein signaling 17

1

0

High-throughput

0.460

High

288695

NPM3
Nucleoplasmin-3

1

9

High-throughput

0.445

High

430114

JUN
Transcription factor Jun

1

11

High-throughput

0.445

High

601763

HMGA1
High mobility group protein HMG-I/HMG-Y

1

1

High-throughput

0.445

High

810206

RL3
Large ribosomal subunit protein uL3

1

5

High-throughput

0.445

High

960166

RL26
Large ribosomal subunit protein uL24

1

6

High-throughput

0.445

High

1037258

H11
Histone H1.1

1

20

High-throughput

0.445

High

1112082

KRR1
KRR1 small subunit processome component homolog

1

5

High-throughput

0.445

High

1130333

RRP1B
Ribosomal RNA processing protein 1 homolog B

1

5

High-throughput

0.445

High

1139958

RRS1
Ribosome biogenesis regulatory protein homolog

1

3

High-throughput

0.445

High

1239868

CAVN1
Caveolae-associated protein 1

1

1

High-throughput

0.445

High

1252461

LN28B
Protein lin-28 homolog B

1

17

High-throughput

0.445

High

1313901

CA174
UPF0688 protein C1orf174

1

2

High-throughput

0.445

High

1313904

SERB1
SERPINE1 mRNA-binding protein 1

1

9

High-throughput

0.445

High

1313916

PI51A
Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha

1

1

High-throughput

0.445

High

1313918

PYM1
Partner of Y14 and mago

1

1

High-throughput

0.445

High

1146031

K1H1
Keratin, type I cuticular Ha1

1

3

High-throughput

0.439

High

1313909

KIFA3
Kinesin-associated protein 3

1

3

High-throughput

0.439

High

962250

RHOA
Transforming protein RhoA

1

3

High-throughput

0.437

High

1162414

CLPP
ATP-dependent Clp protease proteolytic subunit, mitochondrial

1

1

High-throughput

0.437

High

1276463

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

9

High-throughput

0.437

High

1313902

FBXL6
F-box/LRR-repeat protein 6

1

5

High-throughput

0.437

High

1313905

FBX22
F-box only protein 22

1

1

High-throughput

0.437

High

1313920

KLF16
Krueppel-like factor 16

1

5

High-throughput

0.437

High

1313924

RHOJ
Rho-related GTP-binding protein RhoJ

1

5

High-throughput

0.437

High

1313949

MAFB
Transcription factor MafB

1

12

High-throughput

0.437

High

1136816

MO4L2
Mortality factor 4-like protein 2

1

0

High-throughput

0.426

High

269685

PLXA2
Plexin-A2

1

2

Small-scale

0.417

High

1288144

SL9B2
Sodium/hydrogen exchanger 9B2

1

3

High-throughput

0.407

High

1276205

ATG9A
Autophagy-related protein 9A

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025