HitPredict

Interactor 1: IN80E (Q8NBZ0)
INO80 complex subunit E (Coiled-coil domain-containing protein 95)
Gene: INO80E

Interactor 2: RUVB1 (Q9Y265)
RuvB-like 1 (EC 3.6.4.12) (49 kDa TATA box-binding protein-interacting protein) (49 kDa TBP-interacting protein) (54 kDa erythrocyte cytosolic protein) (ECP-54) (INO80 complex subunit H) (Nuclear matrix protein 238) (NMP 238) (Pontin 52) (TIP49a) (TIP60-associated protein 54-alpha) (TAP54-alpha)
Gene: RUVBL1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.91	0.60	0.742

The method score is based on:

Property	Details
Experiments	28514442, 33961781, 17721549, 18922472, 16230350, 27939641, 21303910
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type	physical association, association

The annotation score is based on:

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000723 - telomere maintenance GO:0005654 - nucleoplasm GO:0006275 - regulation of DNA replication GO:0006281 - DNA repair GO:0006282 - regulation of DNA repair and 10 others more... GO:0006310 - DNA recombination GO:0006338 - chromatin remodeling GO:0031011 - Ino80 complex GO:0033044 - regulation of chromosome organization GO:0045739 - positive regulation of DNA repair GO:0045893 - positive regulation of DNA-templated transcription GO:0045995 - regulation of embryonic development GO:0051726 - regulation of cell cycle GO:0060382 - regulation of DNA strand elongation GO:1904507 - positive regulation of telomere maintenance in response to DNA damage
Homologous interactions	2

Homologous interactions

Color coding for hit scores

	1	244
Hs

1	456

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024