Interactor 1: SEN2 (Q8NCE0)
tRNA-splicing endonuclease subunit Sen2 (EC 4.6.1.16) (tRNA-intron endonuclease Sen2) (HsSen2)
Gene: TSEN2

Interactor 2: SEN15 (Q8WW01)
tRNA-splicing endonuclease subunit Sen15 (SEN15 homolog) (HsSEN15) (tRNA-intron endonuclease Sen15)
Gene: TSEN15

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.74 0.90 0.816

The method score is based on:

Property Details
Experiments 28514442, 15109492, 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Sen15~tRNA_int_endo
Common GO terms GO:0003676 - nucleic acid binding
GO:0005654 - nucleoplasm
GO:0005730 - nucleolus
GO:0006388 - tRNA splicing, via endonucleolytic cleavage and ligation
GO:0006397 - mRNA processing
Homologous interactions 0

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Last updated: 15 Jul 2024