HitPredict

Interactor 1: RFWD3 (Q6PCD5)
E3 ubiquitin-protein ligase RFWD3 (EC 2.3.2.27) (RING finger and WD repeat domain-containing protein 3) (RING finger protein 201)
Gene: RFWD3

Interactor 2: TCPH (Q99832)
T-complex protein 1 subunit eta (TCP-1-eta) (EC 3.6.1.-) (CCT-eta) (Chaperonin containing T-complex polypeptide 1 subunit 7) (HIV-1 Nef-interacting protein) [Cleaved into: T-complex protein 1 subunit eta, N-terminally processed]
Gene: CCT7

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.75	0.60	0.675

Property	Details
Experiments	26496610, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 774 Hs			1 543
+	Hs
		881987 RFWD3_HUMAN (1-774): 0: 850: 100.00		TCPG_HUMAN (1-541): 0: 577: 31.09
+	Hs
		876025 RFWD3_HUMAN (1-774): 0: 850: 100.00		TCPE_HUMAN (3-527): 0: 557: 29.59
+	Hs
		610723 RFWD3_HUMAN (1-774): 0: 850: 100.00		TCPA_HUMAN (2-533): 0: 544: 34.54
+	Hs
		899442 RFWD3_HUMAN (1-774): 0: 850: 100.00		TCPD_HUMAN (24-520): 4.06e-90: 288: 33.79
+	Hs
		882108 RING2_HUMAN (234-441): 2.45e-31: 127: 15.39		TCPG_HUMAN (1-541): 0: 577: 31.09
+	Hs
		623189 RO52_HUMAN (283-513): 6.51e-27: 117: 13.07		TCPG_HUMAN (1-541): 0: 577: 31.09
+	Hs
		876135 RING2_HUMAN (234-441): 2.45e-31: 127: 15.39		TCPE_HUMAN (3-527): 0: 557: 29.59
+	Hs
		623201 RO52_HUMAN (283-513): 6.51e-27: 117: 13.07		TCPD_HUMAN (24-520): 4.06e-90: 288: 33.79