HitPredict

Interactor 1: TCPE (P48643)
T-complex protein 1 subunit epsilon (TCP-1-epsilon) (EC 3.6.1.-) (CCT-epsilon) (Chaperonin containing T-complex polypeptide 1 subunit 5)
Gene: CCT5

Interactor 2: RFWD3 (Q6PCD5)
E3 ubiquitin-protein ligase RFWD3 (EC 2.3.2.27) (RING finger and WD repeat domain-containing protein 3) (RING finger protein 201)
Gene: RFWD3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.50	0.574

Property	Details
Experiments	26496610, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 541 Hs			1 774
+	Hs
		881987 TCPG_HUMAN (14-540): 0: 574: 33.15		RFWD3_HUMAN (1-774): 0: 850: 100.00
+	Hs
		1243717 TCPH_HUMAN (12-539): 0: 572: 29.64		RFWD3_HUMAN (1-774): 0: 850: 100.00
+	Hs
		610723 TCPA_HUMAN (26-541): 0: 548: 32.08		RFWD3_HUMAN (1-774): 0: 850: 100.00
+	Hs
		899442 TCPD_HUMAN (36-533): 1.62e-107: 333: 39.80		RFWD3_HUMAN (1-774): 0: 850: 100.00
+	Hs
		876135 TCPE_HUMAN (1-541): 0: 637: 100.00		RING2_HUMAN (234-441): 2.45e-31: 127: 15.39
+	Hs
		882108 TCPG_HUMAN (14-540): 0: 574: 33.15		RING2_HUMAN (234-441): 2.45e-31: 127: 15.39
+	Hs
		623189 TCPG_HUMAN (14-540): 0: 574: 33.15		RO52_HUMAN (283-513): 6.51e-27: 117: 13.07
+	Hs
		623201 TCPD_HUMAN (36-533): 1.62e-107: 333: 39.80		RO52_HUMAN (283-513): 6.51e-27: 117: 13.07