HitPredict

Interactor 1: SYNE1 (Q8NF91)
Nesprin-1 (Enaptin) (KASH domain-containing protein 1) (KASH1) (Myocyte nuclear envelope protein 1) (Myne-1) (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1)
Gene: SYNE1

Interactor 2: CDC5L (Q99459)
Cell division cycle 5-like protein (Cdc5-like protein) (Pombe cdc5-related protein)
Gene: CDC5L

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.55	0.60	0.576

Property	Details
Experiments	17043677, unassigned1973
Identification Methods	two hybrid, two hybrid fragment pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0016020 - membrane
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 8797 Hs			1 802
+	Hs
		1263712 SYNE2_HUMAN (2840-8740): 2.87e-69: 265: 8.94		CDC5L_HUMAN (1-802): 0: 756: 100.00
+	Hs
		974135 DYST_HUMAN (12-1547): 1.58e-42: 177: 13.83		CDC5L_HUMAN (1-802): 0: 756: 100.00
+	Hs
		1068641 PLEC_HUMAN (7019-8757): 8.37e-37: 158: 9.89		CDC5L_HUMAN (1-802): 0: 756: 100.00
+	Hs
		1303862 MACF1_HUMAN (7352-8757): 1.08e-27: 128: 11.64		CDC5L_HUMAN (1-802): 0: 756: 100.00
+	Hs
		963400 SPTB2_HUMAN (4116-5904): 9.82e-28: 128: 9.49		CDC5L_HUMAN (1-802): 0: 756: 100.00
+	Hs
		1045493 SPTN1_HUMAN (7955-8728): 7.08e-25: 118: 13.61		CDC5L_HUMAN (1-802): 0: 756: 100.00
+	Hs
		486891 SPTB2_HUMAN (4116-5904): 9.82e-28: 128: 9.49		MYBB_HUMAN (4-527): 1.91e-47: 182: 16.51
+	Hs
		486785 SPTN1_HUMAN (7955-8728): 7.08e-25: 118: 13.61		MYB_HUMAN (398-727): 5.82e-27: 119: 12.06