HitPredict

Interactor 1: LFTY2 (O00292)
Left-right determination factor 2 (Endometrial bleeding-associated factor) (Left-right determination factor A) (Protein lefty-2) (Protein lefty-A) (Transforming growth factor beta-4) (TGF-beta-4)
Gene: LEFTY2

Interactor 2: LFTY1 (O75610)
Left-right determination factor 1 (Left-right determination factor B) (Protein lefty-1) (Protein lefty-B)
Gene: LEFTY1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.65 1.00 0.811

The method score is based on:

Property Details
Experiments 28514442, 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains TGF_beta~TGF_beta, TGF_beta~TGFb_propeptide, TGFb_propeptide~TGFb_propeptide
Common GO terms GO:0005125 - cytokine activity
GO:0005160 - transforming growth factor beta receptor binding
GO:0005615 - extracellular space
GO:0008083 - growth factor activity
GO:0009948 - anterior/posterior axis specification
Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 366
Hs

1 366
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Last updated: 15 Jul 2024