HitPredict

Interactor 1: NEDD1 (Q8NHV4)
Protein NEDD1 (Neural precursor cell expressed developmentally down-regulated protein 1) (NEDD-1)
Gene: NEDD1

Interactor 2: TCPH (Q99832)
T-complex protein 1 subunit eta (TCP-1-eta) (CCT-eta) (Chaperonin containing T-complex polypeptide 1 subunit 7) (HIV-1 Nef-interacting protein) [Cleaved into: T-complex protein 1 subunit eta, N-terminally processed]
Gene: CCT7

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.81	0.60	0.699

Property	Details
Experiments	28514442, 33961781, 26496610, 23443559
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 660 Hs			1 543
+	Hs
		826780 NEDD1_HUMAN (1-660): 7.8e-168: 496: 98.49		TCPG_HUMAN (1-541): 0: 577: 31.09
+	Hs
		821323 NEDD1_HUMAN (1-660): 7.8e-168: 496: 98.49		TCPE_HUMAN (3-527): 0: 557: 29.59
+	Hs
		573380 NEDD1_HUMAN (1-660): 7.8e-168: 496: 98.49		TCPA_HUMAN (2-533): 0: 544: 34.54
+	Hs
		197078 PRP4_HUMAN (73-361): 3.77e-67: 230: 15.28		TCPH_HUMAN (1-543): 0: 647: 100.00
+	Hs
		903467 WDR5_HUMAN (160-480): 6.21e-55: 192: 16.67		TCPH_HUMAN (1-543): 0: 647: 100.00
+	Hs
		826784 POC1B_HUMAN (3-263): 1.84e-70: 238: 19.92		TCPG_HUMAN (1-541): 0: 577: 31.09
+	Hs
		196973 PRP4_HUMAN (73-361): 3.77e-67: 230: 15.28		TCPG_HUMAN (1-541): 0: 577: 31.09
+	Hs
		821326 POC1B_HUMAN (3-263): 1.84e-70: 238: 19.92		TCPE_HUMAN (3-527): 0: 557: 29.59
+	Hs
		196971 PRP4_HUMAN (73-361): 3.77e-67: 230: 15.28		TCPE_HUMAN (3-527): 0: 557: 29.59
+	Hs
		843295 NEDD1_HUMAN (1-660): 7.8e-168: 496: 98.49		TCPD_HUMAN (24-520): 4.05e-90: 288: 33.79
+	Hs
		573384 POC1B_HUMAN (3-263): 1.84e-70: 238: 19.92		TCPA_HUMAN (2-533): 0: 544: 34.54
+	Hs
		196954 PRP4_HUMAN (73-361): 3.77e-67: 230: 15.28		TCPA_HUMAN (2-533): 0: 544: 34.54
+	Hs
		826601 WDR5_HUMAN (160-480): 6.21e-55: 192: 16.67		TCPG_HUMAN (1-541): 0: 577: 31.09
+	Hs
		826748 WDR5B_HUMAN (151-482): 1.01e-52: 186: 15.52		TCPG_HUMAN (1-541): 0: 577: 31.09
+	Hs
		821152 WDR5_HUMAN (160-480): 6.21e-55: 192: 16.67		TCPE_HUMAN (3-527): 0: 557: 29.59
+	Hs
		573201 WDR5_HUMAN (160-480): 6.21e-55: 192: 16.67		TCPA_HUMAN (2-533): 0: 544: 34.54
+	Hs
		573346 WDR5B_HUMAN (151-482): 1.01e-52: 186: 15.52		TCPA_HUMAN (2-533): 0: 544: 34.54
+	Hs
		843299 POC1B_HUMAN (3-263): 1.84e-70: 238: 19.92		TCPD_HUMAN (24-520): 4.05e-90: 288: 33.79
+	Hs
		196979 PRP4_HUMAN (73-361): 3.77e-67: 230: 15.28		TCPD_HUMAN (24-520): 4.05e-90: 288: 33.79
+	Hs
		843139 WDR5_HUMAN (160-480): 6.21e-55: 192: 16.67		TCPD_HUMAN (24-520): 4.05e-90: 288: 33.79