HitPredict

Interactor 1: WDR36 (Q8NI36)
WD repeat-containing protein 36 (T-cell activation WD repeat-containing protein) (TA-WDRP)
Gene: WDR36

Interactor 2: UTP4 (Q969X6)
U3 small nucleolar RNA-associated protein 4 homolog (Cirhin) (UTP4 small subunit processome component)
Gene: UTP4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	ANAPC4_WD40~WD40
Common GO terms	GO:0003723 - RNA binding GO:0005654 - nucleoplasm GO:0032040 - small-subunit processome GO:0042274 - ribosomal small subunit biogenesis
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 951 Hs			1 686
+	Hs
		1016302 WDR36_HUMAN (1-951): 0: 622: 100.00		TBL3_HUMAN (154-681): 9.78e-51: 191: 10.06
+	Sc
		985819 UTP21_YEAST (57-949): 1.79e-127: 410: 29.48		UTP4_YEAST (6-666): 1.08e-126: 395: 22.92
+	Hs
		1246502 WDR36_HUMAN (1-951): 0: 622: 100.00		WDR3_HUMAN (402-635): 3.61e-32: 135: 12.86
+	Hs
		903379 WDR36_HUMAN (1-951): 0: 622: 100.00		WDR5_HUMAN (514-677): 1.36e-20: 95.3: 12.20
+	Hs
		1246488 WDR36_HUMAN (1-951): 0: 622: 100.00		NLE1_HUMAN (563-681): 2.39e-11: 68.7: 10.83
+	Sc
		985425 UTP13_YEAST (144-695): 3.95e-50: 192: 17.28		UTP4_YEAST (6-666): 1.08e-126: 395: 22.92
+	Hs
		1016345 TBL3_HUMAN (2-361): 3.23e-60: 222: 14.88		WDR3_HUMAN (402-635): 3.61e-32: 135: 12.86
+	Dm
		1176809 Q9VE98_DROME (4-317): 2.55e-42: 169: 11.11		Q7JQT9_DROME (2-309): 1.14e-46: 179: 14.02
+	Dm
		1176810 Q9VFV8_DROME (38-557): 1.12e-41: 167: 10.10		Q7JQT9_DROME (2-309): 1.14e-46: 179: 14.02
+	Hs
		1240442 POC1B_HUMAN (69-326): 7.73e-55: 199: 15.91		POC1A_HUMAN (2-128): 4.51e-32: 130: 16.54
+	Hs
		903174 TBL3_HUMAN (2-361): 3.23e-60: 222: 14.88		WDR5_HUMAN (514-677): 1.36e-20: 95.3: 12.20
+	Mm
		291416 WDR1_MOUSE (169-733): 6.62e-62: 223: 12.98		SKI8_MOUSE (98-315): 2.84e-18: 87.9: 15.77
+	Hs
		903349 WDR5B_HUMAN (50-360): 2.1e-59: 208: 14.82		WDR5_HUMAN (514-677): 1.36e-20: 95.3: 12.20
+	Hs
		725410 COPB2_HUMAN (325-850): 2.34e-52: 200: 7.88		WDR5_HUMAN (514-677): 1.36e-20: 95.3: 12.20
+	Bt
		725371 COPB2_BOVIN (325-648): 2.66e-52: 200: 9.45		COPA_BOVIN (1-158): 5.11e-13: 74.9: 13.13
+	Hs
		725372 COPB2_HUMAN (325-850): 2.34e-52: 200: 7.88		COPB2_HUMAN (478-612): 1.11e-12: 73.4: 17.04
+	Hs
		793026 KTNB1_HUMAN (331-633): 1.83e-28: 124: 16.34		LIS1_HUMAN (480-682): 9.65e-32: 129: 6.40