HitPredict

Interactor 1: RUB2 (Q8RUC6)
Ubiquitin-NEDD8-like protein RUB2 [Cleaved into: Ubiquitin; NEDD8-like protein RUB2 (Ubiquitin-related protein 2) (AtRUB2)]
Gene: RUB2

Interactor 2: CUL1 (Q94AH6)
Cullin-1
Gene: CUL1

Species: Arabidopsis thaliana

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	15319484
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Cullin~ubiquitin, Cullin_Nedd8~ubiquitin
Common GO terms	GO:0005634 - nucleus GO:0006511 - ubiquitin-dependent protein catabolic process GO:0016567 - protein ubiquitination GO:0031625 - ubiquitin protein ligase binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 154 At			1 738
+	At
		1091919 UBQ3_ARATH (1-152): 3.65e-59: 187: 80.26		CUL1_ARATH (1-738): 0: 837: 100.00
+	Hs
		475728 UBC_HUMAN (1-153): 1.08e-56: 189: 77.78		CUL3_HUMAN (1-738): 0: 796: 30.09
+	Hs
		475729 UBC_HUMAN (1-153): 1.08e-56: 189: 77.78		CUL4A_HUMAN (13-738): 0: 788: 34.61
+	Hs
		475024 UBB_HUMAN (1-152): 3.59e-61: 190: 78.29		CUL4B_HUMAN (12-738): 0: 774: 32.93
+	Hs
		475730 UBC_HUMAN (1-153): 1.08e-56: 189: 77.78		CUL4B_HUMAN (12-738): 0: 774: 32.93
+	At
		1277343 RUB1_ARATH (77-154): 8.71e-23: 89.6: 58.97		CUL1_ARATH (1-738): 0: 837: 100.00
+	Hs
		475726 UBC_HUMAN (1-153): 1.08e-56: 189: 77.78		CUL1_HUMAN (4-738): 0: 729: 30.41
+	Rn
		78188 UBC_RAT (1-105): 4.67e-31: 118: 80.95		CUL3_RAT (1-738): 0: 795: 30.09
+	Mm
		477034 UBC_MOUSE (1-105): 4.14e-31: 118: 82.86		CUL3_MOUSE (1-738): 0: 794: 30.09
+	Rn
		71349 UBC_RAT (1-105): 4.67e-31: 118: 80.95		B2RYJ3_RAT (13-738): 0: 783: 33.52
+	Hs
		923983 RS27A_HUMAN (77-152): 7.36e-27: 99: 60.53		CUL3_HUMAN (1-738): 0: 796: 30.09
+	Hs
		923984 RS27A_HUMAN (77-152): 7.36e-27: 99: 60.53		CUL4A_HUMAN (13-738): 0: 788: 34.61
+	Hs
		475727 UBC_HUMAN (1-153): 1.08e-56: 189: 77.78		CUL2_HUMAN (1-738): 0: 688: 27.05
+	Hs
		923985 RS27A_HUMAN (77-152): 7.36e-27: 99: 60.53		CUL4B_HUMAN (12-738): 0: 774: 32.93
+	Sp
		142914 UBI4P_SCHPO (1-153): 3.18e-57: 184: 79.09		CUL1_SCHPO (3-738): 0: 680: 27.94
+	Rn
		70071 UBC_RAT (1-105): 4.67e-31: 118: 80.95		B1WBY1_RAT (4-738): 0: 729: 30.41
+	Mm
		477001 UBC_MOUSE (1-105): 4.14e-31: 118: 82.86		CUL2_MOUSE (1-738): 0: 694: 26.53
+	Hs
		476148 UBC_HUMAN (1-153): 1.08e-56: 189: 77.78		CUL5_HUMAN (3-738): 0: 615: 24.14
+	Rn
		1144279 UBC_RAT (1-105): 4.67e-31: 118: 80.95		CUL5_RAT (3-738): 0: 613: 24.27
+	Mm
		477002 UBC_MOUSE (1-105): 4.14e-31: 118: 82.86		CUL5_MOUSE (3-738): 0: 609: 24.40