HitPredict

Interactor 1: Q8SY34 (Q8SY34)
LD46604p (Myosin phosphatase targeting subunit 75D, isoform A) (Myosin phosphatase targeting subunit 75D, isoform C) (Myosin phosphatase targeting subunit 75D, isoform D)
Gene: MYPT-75D

Interactor 2: Q8T0U6 (Q8T0U6)
Serine/threonine-protein phosphatase (EC 3.1.3.16)
Gene: flw

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.50	0.60	0.552

Property	Details
Experiments	21447707, 25294943
Identification Methods	interactome parallel affinity capture, pull down
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0017018 - myosin phosphatase activity
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 741 Dm			1 461
+	Dm
		819281 Q8SY34_DROME (1-741): 9.93e-132: 409: 100.00		PP1B_DROME (142-461): 0: 594: 97.21
+	Dm
		819272 Q86R99_DROME (43-547): 7.98e-91: 303: 28.19		PP1B_DROME (142-461): 0: 594: 97.21
+	Ce
		953872 P90902_CAEEL (115-523): 1e-100: 320: 38.37		GLC7A_CAEEL (149-460): 0: 574: 86.54
+	Ce
		1099876 Q95ZS1_CAEEL (115-523): 2.18e-99: 316: 38.02		GLC7A_CAEEL (149-460): 0: 574: 86.54
+	Hs
		906572 PP16B_HUMAN (24-535): 2.18e-90: 296: 36.40		PP1B_HUMAN (136-460): 0: 586: 85.93
+	Hs
		905838 ANK2_HUMAN (1-366): 1.14e-85: 299: 22.16		PP1A_HUMAN (141-457): 0: 581: 81.99
+	Hs
		225133 MYPT2_HUMAN (40-390): 1.1e-85: 293: 34.09		PP1B_HUMAN (136-460): 0: 586: 85.93
+	Hs
		906099 PP16B_HUMAN (24-535): 2.18e-90: 296: 36.40		PP1A_HUMAN (141-457): 0: 581: 81.99
+	Hs
		737999 PP16B_HUMAN (24-535): 2.18e-90: 296: 36.40		PP1G_HUMAN (142-461): 0: 579: 81.37
+	Hs
		225132 MYPT2_HUMAN (40-390): 1.1e-85: 293: 34.09		PP1A_HUMAN (141-457): 0: 581: 81.99
+	Hs
		225129 MYPT2_HUMAN (40-390): 1.1e-85: 293: 34.09		PP1G_HUMAN (142-461): 0: 579: 81.37
+	Hs
		906561 PP16A_HUMAN (24-542): 2.14e-86: 284: 38.29		PP1B_HUMAN (136-460): 0: 586: 85.93
+	Hs
		161348 MYPT1_HUMAN (110-488): 1.76e-81: 282: 29.43		PP1B_HUMAN (136-460): 0: 586: 85.93
+	Gg
		907234 MYPT1_CHICK (117-488): 1.12e-81: 282: 31.90		PP1B_CHICK (136-460): 0: 586: 85.93
+	Hs
		906079 PP16A_HUMAN (24-542): 2.14e-86: 284: 38.29		PP1A_HUMAN (141-457): 0: 581: 81.99
+	Hs
		161347 MYPT1_HUMAN (110-488): 1.76e-81: 282: 29.43		PP1A_HUMAN (141-457): 0: 581: 81.99
+	Hs
		737978 PP16A_HUMAN (24-542): 2.14e-86: 284: 38.29		PP1G_HUMAN (142-461): 0: 579: 81.37
+	Hs
		161322 MYPT1_HUMAN (110-488): 1.76e-81: 282: 29.43		PP1G_HUMAN (142-461): 0: 579: 81.37
+	Mm
		906366 MYPT1_MOUSE (110-429): 2.44e-80: 279: 33.33		PP1A_MOUSE (141-457): 0: 582: 81.68
+	Mm
		926555 MYPT1_MOUSE (110-429): 2.44e-80: 279: 33.33		PP1G_MOUSE (142-461): 0: 579: 81.37