Protein: CERS1
Ceramide synthase 1 (CerS1) (LAG1 longevity assurance homolog 1) (Longevity assurance gene 1 protein homolog 1) (Protein UOG-1) (Sphingoid base N-stearoyltransferase CERS1) (EC 2.3.1.299)

Gene: CERS1
Organism: Homo sapiens
Interactions: 41
UniProt ID: P27544

Gene Ontology (top 5):
GO:0005783 - endoplasmic reticulum
GO:0005789 - endoplasmic reticulum membrane
GO:0007420 - brain development
GO:0010614 - negative regulation of cardiac muscle hypertrophy
GO:0016020 - membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

693391

BKRB1
B1 bradykinin receptor

1

15

High-throughput

0.541

High

693400

5HT4R
5-hydroxytryptamine receptor 4

1

11

High-throughput

0.541

High

693416

LT4R2
Leukotriene B4 receptor 2

1

20

High-throughput

0.541

High

619518

VCAM1
Vascular cell adhesion protein 1

1

1

High-throughput

0.536

High

693414

SG196
Protein O-mannose kinase

1

4

High-throughput

0.536

High

572412

DRD2
D(2) dopamine receptor

1

9

High-throughput

0.494

High

173863

AT2A1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1

1

2

High-throughput

0.479

High

417269

RPN1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

1

2

High-throughput

0.479

High

417955

RPN2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

1

1

High-throughput

0.479

High

693390

SSRA
Translocon-associated protein subunit alpha

1

1

High-throughput

0.479

High

693398

SC61B
Protein transport protein Sec61 subunit beta

1

4

High-throughput

0.479

High

693407

LMBRL
Protein LMBR1L

1

2

High-throughput

0.479

High

693415

TMT1A
Thiol S-methyltransferase TMT1A

1

1

High-throughput

0.479

High

693397

UBP14
Ubiquitin carboxyl-terminal hydrolase 14

1

0

Small-scale

0.458

High

693399

ACTG
Actin, cytoplasmic 2

1

0

Small-scale

0.458

High

693410

PLD3
5'-3' exonuclease PLD3

1

0

High-throughput

0.458

High

178188

NPC1
NPC intracellular cholesterol transporter 1

1

3

High-throughput

0.445

High

182469

GP182
G-protein coupled receptor 182

1

20

High-throughput

0.445

High

255985

S19A2
Thiamine transporter 1

1

5

High-throughput

0.445

High

693387

CALX
Calnexin

1

2

High-throughput

0.445

High

693392

SC6A8
Sodium- and chloride-dependent creatine transporter 1

1

13

High-throughput

0.445

High

693393

S6A12
Sodium- and chloride-dependent betaine transporter

1

13

High-throughput

0.445

High

693394

S6A11
Sodium- and chloride-dependent GABA transporter 3

1

13

High-throughput

0.445

High

693396

SC5A3
Sodium/myo-inositol cotransporter

1

2

High-throughput

0.445

High

693401

S39AE
Metal cation symporter ZIP14

1

8

High-throughput

0.445

High

693409

NIPA1
Magnesium transporter NIPA1

1

3

High-throughput

0.445

High

217856

TGON2
Trans-Golgi network integral membrane protein 2

1

5

High-throughput

0.437

High

293239

CD123
Translation initiation factor eIF2 assembly protein

1

1

High-throughput

0.437

High

693389

CCNF
Cyclin-F

1

1

High-throughput

0.437

High

693406

TECT3
Tectonic-3

1

3

High-throughput

0.437

High

693408

TRI67
Tripartite motif-containing protein 67

1

3

High-throughput

0.437

High

693417

OTULL
Inactive ubiquitin thioesterase OTULINL

1

3

High-throughput

0.437

High

693388

5HT1E
5-hydroxytryptamine receptor 1E

1

10

High-throughput

0.407

High

693402

S15A2
Solute carrier family 15 member 2

1

5

High-throughput

0.407

High

693404

SC5A9
Sodium/glucose cotransporter 4

1

2

High-throughput

0.407

High

693405

S35F1
Solute carrier family 35 member F1

1

9

High-throughput

0.407

High

693411

ZNT7
Zinc transporter 7

1

6

High-throughput

0.407

High

693412

MFSD8
Major facilitator superfamily domain-containing protein 8

1

3

High-throughput

0.407

High

693413

CTR3
Cationic amino acid transporter 3

1

8

High-throughput

0.407

High

693403

MK06
Mitogen-activated protein kinase 6

1

0

High-throughput

0.265

Low

693395

RAB5C
Ras-related protein Rab-5C

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025