HitPredict

Interactor 1: HIPPO (Q8T0S6)
Serine/threonine-protein kinase hippo (EC 2.7.11.1) (Drosophila homolog of MST1 and MST2) (STE20-like kinase MST) (dMST)
Gene: hpo

Interactor 2: Q9VCQ7 (Q9VCQ7)
LD40758p (Ras association family member)
Gene: Rassf

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.91	0.60	0.743

Property	Details
Experiments	20797625, 24114784, 25484297, 17174922, 22215676, 32213597, 15710747
Identification Methods	affinity chromatography technology, pull down, two hybrid
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 669 Dm			1 806
+	Hs
		682035 AKT1_HUMAN (13-360): 6.81e-132: 398: 20.06		RASF1_HUMAN (557-801): 1.53e-82: 269: 20.78
+	Hs
		1026166 PAK1_HUMAN (2-317): 1.29e-115: 358: 35.85		LASP1_HUMAN (2-188): 2.87e-44: 162: 18.04
+	Hs
		1026240 PAK1_HUMAN (2-317): 1.29e-115: 358: 35.85		LIMA1_HUMAN (3-138): 1.58e-29: 127: 23.13
+	Hs
		841548 STK4_HUMAN (537-661): 8.11e-18: 88.9: 29.60		RASF2_HUMAN (550-802): 5.59e-105: 327: 31.42
+	Hs
		841549 STK3_HUMAN (502-661): 1.12e-16: 85.2: 24.22		RASF2_HUMAN (550-802): 5.59e-105: 327: 31.42
+	Hs
		1023066 STK4_HUMAN (537-661): 8.11e-18: 88.9: 29.60		RASF6_HUMAN (550-801): 4.27e-98: 311: 29.55
+	Hs
		1027388 STK3_HUMAN (502-661): 1.12e-16: 85.2: 24.22		RASF6_HUMAN (550-801): 4.27e-98: 311: 29.55
+	Hs
		1023109 STK4_HUMAN (537-661): 8.11e-18: 88.9: 29.60		RASF4_HUMAN (550-802): 8.61e-87: 279: 32.30
+	Hs
		1027429 STK3_HUMAN (502-661): 1.12e-16: 85.2: 24.22		RASF4_HUMAN (550-802): 8.61e-87: 279: 32.30
+	Hs
		1023125 STK4_HUMAN (537-661): 8.11e-18: 88.9: 29.60		RASF1_HUMAN (557-801): 1.53e-82: 269: 20.78
+	Hs
		1027444 STK3_HUMAN (502-661): 1.12e-16: 85.2: 24.22		RASF1_HUMAN (557-801): 1.53e-82: 269: 20.78
+	Hs
		1023077 STK4_HUMAN (537-661): 8.11e-18: 88.9: 29.60		RASF3_HUMAN (524-802): 8.09e-79: 255: 18.44
+	Hs
		1027396 STK3_HUMAN (502-661): 1.12e-16: 85.2: 24.22		RASF3_HUMAN (524-802): 8.09e-79: 255: 18.44
+	Mm
		1125492 STK4_MOUSE (547-661): 1.79e-17: 87.8: 29.17		RASF5_MOUSE (555-801): 7.44e-71: 240: 23.86
+	Hs
		1023084 STK4_HUMAN (537-661): 8.11e-18: 88.9: 29.60		RASF5_HUMAN (555-801): 9.16e-68: 232: 20.97
+	Hs
		1027406 STK3_HUMAN (502-661): 1.12e-16: 85.2: 24.22		RASF5_HUMAN (555-801): 9.16e-68: 232: 20.97
+	Hs
		1023049 STK4_HUMAN (537-661): 8.11e-18: 88.9: 29.60		CSRP2_HUMAN (3-184): 3.56e-38: 142: 18.18