HitPredict

Interactor 1: HIPPO (Q8T0S6)
Serine/threonine-protein kinase hippo (EC 2.7.11.1) (Drosophila homolog of MST1 and MST2) (STE20-like kinase MST) (dMST)
Gene: hpo

Interactor 2: Q9W5R5 (Q9W5R5)
LD47843p (Sarcolemma associated protein, isoform A) (Sarcolemma associated protein, isoform D)
Gene: Slmap

Species: Drosophila melanogaster

Source: dip

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.70	1.00	0.839

Property	Details
Experiments	29262338, 15710747, 22036573
Identification Methods	affinity chromatography technology, two hybrid
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	FHA~Pkinase
Common GO terms	GO:0005737 - cytoplasm GO:0016020 - membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 669 Dm			1 897
+	Hs
		568834 KAPCA_HUMAN (6-346): 3.17e-130: 389: 21.94		T3JAM_HUMAN (338-609): 1.88e-56: 205: 22.10
+	Hs
		1376977 STK24_HUMAN (33-316): 5.77e-120: 366: 51.39		T3JAM_HUMAN (338-609): 1.88e-56: 205: 22.10
+	Hs
		131621 STK25_HUMAN (26-392): 9.65e-118: 360: 41.24		T3JAM_HUMAN (338-609): 1.88e-56: 205: 22.10
+	Hs
		1350183 STK26_HUMAN (32-406): 1.7e-117: 359: 40.10		T3JAM_HUMAN (338-609): 1.88e-56: 205: 22.10
+	Hs
		282546 AKT1_HUMAN (13-360): 6.81e-132: 398: 20.06		RNF8_HUMAN (257-690): 2.03e-30: 128: 14.65
+	Hs
		647929 MARK3_HUMAN (11-664): 2.35e-136: 419: 15.26		DLG5_HUMAN (336-754): 1.76e-15: 83.5: 10.70
+	Hs
		1183078 MARK2_HUMAN (3-614): 2.18e-132: 410: 15.72		DLG5_HUMAN (336-754): 1.76e-15: 83.5: 10.70
+	Hs
		681696 AKT1_HUMAN (13-360): 6.81e-132: 398: 20.06		MYH9_HUMAN (518-896): 1.36e-13: 77.6: 12.40
+	Hs
		528359 KAPCB_HUMAN (6-342): 3.49e-129: 387: 21.90		MYH6_HUMAN (273-880): 6.09e-17: 88.4: 11.64
+	Hs
		129013 PLK4_HUMAN (40-641): 1.11e-128: 405: 19.44		MRCKA_HUMAN (697-883): 3.47e-10: 66.5: 12.87
+	Hs
		568567 KAPCA_HUMAN (6-346): 3.17e-130: 389: 21.94		MYH9_HUMAN (518-896): 1.36e-13: 77.6: 12.40
+	Hs
		610795 KAPCB_HUMAN (6-342): 3.49e-129: 387: 21.90		MYH2_HUMAN (334-863): 5.04e-14: 78.9: 14.03
+	Hs
		551616 AKT1_HUMAN (13-360): 6.81e-132: 398: 20.06		DESP_HUMAN (314-822): 2.89e-09: 63.4: 15.65
+	Hs
		522538 KAPCB_HUMAN (6-342): 3.49e-129: 387: 21.90		MYH1_HUMAN (319-815): 1.06e-11: 71.2: 12.43
+	Hs
		1344754 SNRK_HUMAN (41-412): 1.65e-115: 365: 24.68		MYH2_HUMAN (334-863): 5.04e-14: 78.9: 14.03
+	Hs
		522572 SNRK_HUMAN (41-412): 1.65e-115: 365: 24.68		MYH1_HUMAN (319-815): 1.06e-11: 71.2: 12.43
+	Hs
		1061903 STK24_HUMAN (33-316): 5.77e-120: 366: 51.39		SLMAP_HUMAN (287-766): 4e-11: 69.1: 9.90
+	Hs
		551881 STK24_HUMAN (33-316): 5.77e-120: 366: 51.39		DESP_HUMAN (314-822): 2.89e-09: 63.4: 15.65
+	Hs
		131570 STK25_HUMAN (26-392): 9.65e-118: 360: 41.24		SLMAP_HUMAN (287-766): 4e-11: 69.1: 9.90
+	Hs
		1061892 STK26_HUMAN (32-406): 1.7e-117: 359: 40.10		SLMAP_HUMAN (287-766): 4e-11: 69.1: 9.90