Protein: BT2A1
Butyrophilin subfamily 2 member A1

Gene: BT2A1, BTN2A1
Organism: Homo sapiens
Interactions: 66
UniProt ID: Q7KYR7

Gene Ontology (top 5):
GO:0001817 - regulation of cytokine production
GO:0005102 - signaling receptor binding
GO:0005886 - plasma membrane
GO:0006629 - lipid metabolic process
GO:0009897 - external side of plasma membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

627539

DPA1
HLA class II histocompatibility antigen, DP alpha 1 chain

3

11

High-throughput

0.861

High

1270275

BT2A2
Butyrophilin subfamily 2 member A2

3

16

High-throughput

0.861

High

705966

CD1B
T-cell surface glycoprotein CD1b

2

10

High-throughput

0.811

High

332221

UCP5
Brain mitochondrial carrier protein 1

2

8

High-throughput

0.789

High

1270272

CLD19
Claudin-19

2

2

High-throughput

0.783

High

62972

POTEF
POTE ankyrin domain family member F

3

9

High-throughput

0.770

High

337758

SGPL1
Sphingosine-1-phosphate lyase 1

3

2

High-throughput

0.770

High

1210690

KMCP1
Kidney mitochondrial carrier protein 1

3

8

High-throughput

0.770

High

1270274

PDZD8
PDZ domain-containing protein 8

3

1

High-throughput

0.770

High

1270278

AT2A3
Sarcoplasmic/endoplasmic reticulum calcium ATPase 3

3

7

High-throughput

0.770

High

1270283

TMX4
Thioredoxin-related transmembrane protein 4

3

11

High-throughput

0.770

High

260897

RAMP3
Receptor activity-modifying protein 3

2

0

High-throughput

0.736

High

127694

TR10A
Tumor necrosis factor receptor superfamily member 10A

1

3

High-throughput

0.691

High

522686

PTPRF
Receptor-type tyrosine-protein phosphatase F

1

4

High-throughput

0.691

High

690095

AVR2A
Activin receptor type-2A

1

1

High-throughput

0.691

High

855339

5HT3A
5-hydroxytryptamine receptor 3A

1

3

High-throughput

0.691

High

1270281

OSMR
Oncostatin-M-specific receptor subunit beta

1

6

High-throughput

0.691

High

1270292

MYOF
Myoferlin

1

3

High-throughput

0.691

High

643370

OSBP1
Oxysterol-binding protein 1

3

2

High-throughput

0.667

High

1270291

FMN2
Formin-2

3

3

High-throughput

0.667

High

1116229

PTC1
Protein patched homolog 1

2

7

High-throughput

0.628

High

942378

EP3B
Epididymal secretory protein E3-beta

1

1

High-throughput

0.618

High

1270285

TMX1
Thioredoxin-related transmembrane protein 1

1

12

High-throughput

0.618

High

1034012

OCRL
Inositol polyphosphate 5-phosphatase OCRL

1

2

High-throughput

0.618

High

1270282

ESYT1
Extended synaptotagmin-1

1

2

High-throughput

0.618

High

1270289

TMPS4
Transmembrane protease serine 4

1

4

High-throughput

0.618

High

71346

F1712
Protein FAM171A2

3

1

High-throughput

0.609

High

1139332

RB3GP
Rab3 GTPase-activating protein catalytic subunit

3

1

High-throughput

0.609

High

1270288

PLCB1
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1

3

3

High-throughput

0.609

High

1270290

TYW1
S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase TYW1

3

4

High-throughput

0.609

High

1270271

PLPP6
Polyisoprenoid diphosphate/phosphate phosphohydrolase PLPP6

2

2

High-throughput

0.606

High

1270273

DGLB
Diacylglycerol lipase-beta

1

0

High-throughput

0.586

High

1060362

SLC31
Amino acid transporter heavy chain SLC3A1

1

1

High-throughput

0.575

High

1119179

CAC1C
Voltage-dependent L-type calcium channel subunit alpha-1C

1

5

High-throughput

0.575

High

636232

MAL
Myelin and lymphocyte protein

2

1

High-throughput

0.553

High

1010489

EREP3
Protein ENTREP3

1

1

High-throughput

0.553

High

255089

HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

1

0

High-throughput

0.546

High

658726

JAK1
Tyrosine-protein kinase JAK1

1

15

High-throughput

0.536

High

1245080

RHDF2
Inactive rhomboid protein 2

1

1

High-throughput

0.536

High

698806

CALX
Calnexin

1

4

High-throughput

0.489

High

1218411

CDKAL
Threonylcarbamoyladenosine tRNA methylthiotransferase

1

1

High-throughput

0.489

High

1226692

2ABD
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform

1

1

High-throughput

0.489

High

1270276

ZNRF4
E3 ubiquitin-protein ligase ZNRF4

1

6

High-throughput

0.489

High

1270287

AT131
Endoplasmic reticulum transmembrane helix translocase

1

8

High-throughput

0.489

High

1270293

FBX2
F-box only protein 2

1

4

High-throughput

0.489

High

218371

TGON2
Trans-Golgi network integral membrane protein 2

1

5

High-throughput

0.479

High

223142

PRC1
Protein regulator of cytokinesis 1

1

3

High-throughput

0.479

High

1130701

DIP2A
Disco-interacting protein 2 homolog A

1

2

High-throughput

0.479

High

1270286

MARH7
E3 ubiquitin-protein ligase MARCHF7

1

1

High-throughput

0.479

High

1201840

PKHG4
Puratrophin-1

1

0

High-throughput

0.458

High

399700

HMDH
3-hydroxy-3-methylglutaryl-coenzyme A reductase

1

7

High-throughput

0.437

High

596669

NCPR
NADPH--cytochrome P450 reductase

1

4

High-throughput

0.437

High

634499

LMNB1
Lamin-B1

1

19

High-throughput

0.437

High

1270277

P55G
Phosphatidylinositol 3-kinase regulatory subunit gamma

1

9

High-throughput

0.437

High

170837

CLGN
Calmegin

1

4

High-throughput

0.407

High

72662

UPK3L
Uroplakin-3b-like protein 1

3

0

High-throughput

0.347

High

397605

NU1M
NADH-ubiquinone oxidoreductase chain 1

3

0

High-throughput

0.347

High

1270270

DEN6A
Protein DENND6A

3

0

High-throughput

0.347

High

1270279

ITFG2
KICSTOR complex protein ITFG2

3

0

High-throughput

0.347

High

1270284

GO45
Golgin-45

3

0

High-throughput

0.347

High

1270294

KPTN
KICSTOR complex protein kaptin

2

0

High-throughput

0.318

High

843336

NSG1
Neuronal vesicle trafficking-associated protein 1

2

0

High-throughput

0.316

High

1195528

CTXN3
Cortexin-3

2

0

High-throughput

0.316

High

516270

DWORF
Sarcoplasmic/endoplasmic reticulum calcium ATPase regulator DWORF

1

0

High-throughput

0.268

Low

1238642

TM214
Transmembrane protein 214

1

0

High-throughput

0.249

Low

1270280

TM169
Transmembrane protein 169

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025