HitPredict

Interactor 1: Q8T8V8 (Q8T8V8)
Proteasome subunit beta
Gene: Prosbeta5R1

Interactor 2: PSB4 (Q9VNA5)
Proteasome subunit beta type-4 (Proteasome subunit beta type-7)
Gene: Prosbeta7

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.34	1.00	0.590

Property	Details
Experiments	19079254
Identification Methods	two hybrid array
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Proteasome~Proteasome
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0019774 - proteasome core complex, beta-subunit complex GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 315 Dm			1 268
+	Hs
		156228 PSB8_HUMAN (1-275): 3.36e-104: 307: 42.96		PSA7_HUMAN (33-265): 2.53e-82: 248: 12.55
+	Hs
		638065 PSB8_HUMAN (1-275): 3.36e-104: 307: 42.96		PSA4_HUMAN (32-265): 3.42e-79: 241: 13.33
+	Hs
		656051 PSB8_HUMAN (1-275): 3.36e-104: 307: 42.96		PSA6_HUMAN (28-265): 1.4e-78: 239: 17.55
+	Hs
		656036 PSB8_HUMAN (1-275): 3.36e-104: 307: 42.96		PSB4_HUMAN (12-268): 4.95e-78: 238: 38.91
+	Dm
		1178964 Q7K148_DROME (1-280): 2.97e-98: 292: 59.01		PSB4_DROME (1-268): 1.99e-81: 247: 100.00
+	Hs
		656034 PSB8_HUMAN (1-275): 3.36e-104: 307: 42.96		PSB8_HUMAN (14-257): 1.27e-74: 230: 19.20
+	Dm
		574020 Q7K148_DROME (1-280): 2.97e-98: 292: 59.01		PSA4_DROME (33-268): 1.36e-78: 240: 14.34
+	Dm
		1178944 Q7K148_DROME (1-280): 2.97e-98: 292: 59.01		PSA5_DROME (33-266): 1.46e-77: 236: 17.00
+	Dm
		611640 Q7K148_DROME (1-280): 2.97e-98: 292: 59.01		PSA71_DROME (32-265): 1.61e-77: 236: 12.50
+	Hs
		656038 PSB8_HUMAN (1-275): 3.36e-104: 307: 42.96		PSB5_HUMAN (15-247): 2.34e-71: 221: 18.03
+	Hs
		656076 PSB8_HUMAN (1-275): 3.36e-104: 307: 42.96		PSB7_HUMAN (23-260): 1.37e-69: 217: 19.58
+	Hs
		156233 PSB5_HUMAN (1-275): 1.81e-90: 272: 46.18		PSA7_HUMAN (33-265): 2.53e-82: 248: 12.55
+	Hs
		594453 PSB8_HUMAN (1-275): 3.36e-104: 307: 42.96		PSB1_HUMAN (22-248): 5.77e-66: 207: 19.66
+	Hs
		656042 PSB8_HUMAN (1-275): 3.36e-104: 307: 42.96		PSB10_HUMAN (26-257): 7.3e-66: 207: 17.67
+	Hs
		638070 PSB5_HUMAN (1-275): 1.81e-90: 272: 46.18		PSA4_HUMAN (32-265): 3.42e-79: 241: 13.33
+	Dm
		1178968 Q7K148_DROME (1-280): 2.97e-98: 292: 59.01		Q9VUJ1_DROME (60-260): 6.76e-69: 215: 19.40
+	Hs
		594458 PSB5_HUMAN (1-275): 1.81e-90: 272: 46.18		PSB1_HUMAN (22-248): 5.77e-66: 207: 19.66
+	Dm
		771401 Q7K148_DROME (1-280): 2.97e-98: 292: 59.01		PSB1_DROME (29-251): 2.59e-58: 187: 23.08
+	Dm
		1178962 Q7K148_DROME (1-280): 2.97e-98: 292: 59.01		Q9VJJ0_DROME (59-257): 1.07e-21: 91.3: 19.60
+	Dm
		47604 Q7K148_DROME (1-280): 2.97e-98: 292: 59.01		A0AQH0_DROME (50-248): 6.38e-21: 89.8: 16.08