HitPredict

Interactor 1: ZCRB1 (Q8TBF4)
Zinc finger CCHC-type and RNA-binding motif-containing protein 1 (U11/U12 small nuclear ribonucleoprotein 31 kDa protein) (U11/U12 snRNP 31 kDa protein) (U11/U12-31K)
Gene: ZCRB1

Interactor 2: DDX21 (Q9NR30)
Nucleolar RNA helicase 2 (EC 3.6.4.13) (DEAD box protein 21) (Gu-alpha) (Nucleolar RNA helicase Gu) (Nucleolar RNA helicase II) (RH II/Gu)
Gene: DDX21

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 217 Hs			1 783
+	Hs
		516711 PABP1_HUMAN (11-99): 1.42e-22: 96.9: 19.10		DDX21_HUMAN (1-783): 0: 543: 100.00
+	Hs
		1314627 RBM4_HUMAN (11-103): 1.52e-18: 84.2: 21.51		DDX21_HUMAN (1-783): 0: 543: 100.00
+	Mm
		936482 TIAR_MOUSE (3-142): 2.86e-18: 83.9: 14.89		Q8K2L4_MOUSE (101-783): 2.92e-167: 501: 86.17
+	Hs
		1084383 SRSF7_HUMAN (9-120): 7.54e-35: 125: 32.17		DDX50_HUMAN (49-728): 1.52e-137: 425: 59.12
+	Hs
		134018 PABP4_HUMAN (11-196): 1.86e-23: 99.6: 12.37		DDX3X_HUMAN (5-575): 3.96e-137: 422: 23.55
+	Hs
		133858 PABP1_HUMAN (11-99): 1.42e-22: 96.9: 19.10		DDX3X_HUMAN (5-575): 3.96e-137: 422: 23.55
+	Hs
		1271643 RBM4_HUMAN (11-103): 1.52e-18: 84.2: 21.51		DDX17_HUMAN (122-628): 1.38e-136: 423: 24.46
+	Mm
		936480 TIAR_MOUSE (3-142): 2.86e-18: 83.9: 14.89		DDX5_MOUSE (92-620): 1.44e-136: 419: 24.81
+	Mm
		857323 TIA1_MOUSE (3-125): 7.02e-18: 82.7: 17.89		DDX17_MOUSE (122-628): 3.34e-135: 417: 24.46
+	Hs
		571581 RBM4_HUMAN (11-103): 1.52e-18: 84.2: 21.51		DDX5_HUMAN (92-620): 4.08e-135: 415: 24.81
+	Mm
		857351 TIA1_MOUSE (3-125): 7.02e-18: 82.7: 17.89		Q8BTS0_MOUSE (92-620): 1.47e-135: 416: 24.81
+	Hs
		1073596 SF3B4_HUMAN (101-215): 5.02e-12: 66.1: 9.84		DDX42_HUMAN (2-757): 4.87e-137: 430: 20.41
+	Hs
		1073611 SF3B4_HUMAN (101-215): 5.02e-12: 66.1: 9.84		DDX17_HUMAN (122-628): 1.38e-136: 423: 24.46
+	Hs
		757632 SRSF7_HUMAN (9-120): 7.54e-35: 125: 32.17		IF4A3_HUMAN (169-554): 5.06e-54: 194: 32.23
+	Sc
		376580 PABP_YEAST (11-208): 3.81e-23: 98.5: 15.60		DED1_YEAST (196-541): 2.98e-56: 205: 37.98
+	Hs
		516391 PABP1_HUMAN (11-99): 1.42e-22: 96.9: 19.10		IF4A3_HUMAN (169-554): 5.06e-54: 194: 32.23