Protein: TRI65
E3 ubiquitin-protein ligase TRIM65 (EC 2.3.2.27) (Tripartite motif-containing protein 65)

Gene: TRI65, TRIM65
Organism: Homo sapiens
Interactions: 71
UniProt ID: Q6PJ69

Gene Ontology (top 5):
GO:0001934 - positive regulation of protein phosphorylation
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0008270 - zinc ion binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1162056

IFIH1
Interferon-induced helicase C domain-containing protein 1

2

15

Small-scale

0.839

High

1023485

MKRN3
Probable E3 ubiquitin-protein ligase makorin-3

1

3

High-throughput

0.698

High

1162055

HOIL1
RanBP-type and C3HC4-type zinc finger-containing protein 1

1

13

High-throughput

0.698

High

1162038

CCNJL
Cyclin-J-like protein

3

1

High-throughput

0.667

High

1162061

UBE2Z
Ubiquitin-conjugating enzyme E2 Z

1

20

High-throughput

0.656

High

321907

RIGI
Antiviral innate immune response receptor RIG-I

1

16

Small-scale

0.647

High

896466

UBE2N
Ubiquitin-conjugating enzyme E2 N

1

20

Small-scale

0.647

High

919754

UB2D2
Ubiquitin-conjugating enzyme E2 D2

1

20

High-throughput

0.647

High

386945

P53
Cellular tumor antigen p53

3

7

Small-scale

0.646

High

456339

LOX5
Polyunsaturated fatty acid 5-lipoxygenase

2

2

High-throughput

0.628

High

1162060

DOCK5
Dedicator of cytokinesis protein 5

2

1

High-throughput

0.628

High

1162070

CRYL1
Lambda-crystallin homolog

2

3

High-throughput

0.628

High

1138881

UBE2U
Ubiquitin-conjugating enzyme E2 U

1

20

High-throughput

0.625

High

908710

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

20

High-throughput

0.618

High

1162034

TRI67
Tripartite motif-containing protein 67

1

17

High-throughput

0.618

High

1162041

GALD1
Glutamine amidotransferase-like class 1 domain-containing protein 1

2

0

High-throughput

0.602

High

1162051

SRPK1
SRSF protein kinase 1

1

6

High-throughput

0.569

High

1162043

TNR6A
Trinucleotide repeat-containing gene 6A protein

1

7

High-throughput

0.561

High

787163

RHG25
Rho GTPase-activating protein 25

2

6

High-throughput

0.558

High

1162062

MARH7
E3 ubiquitin-protein ligase MARCHF7

1

1

High-throughput

0.541

High

1162064

APC11
Anaphase-promoting complex subunit 11

1

1

High-throughput

0.541

High

335274

DYR
Dihydrofolate reductase

1

1

High-throughput

0.536

High

1162039

CDK20
Cyclin-dependent kinase 20

1

6

High-throughput

0.536

High

1162048

EFMT3
EEF1A lysine methyltransferase 3

1

1

High-throughput

0.536

High

1162054

DUS16
Dual specificity protein phosphatase 16

1

4

High-throughput

0.536

High

1162058

SHRPN
Sharpin

1

4

High-throughput

0.536

High

180046

P4HA2
Prolyl 4-hydroxylase subunit alpha-2

1

0

High-throughput

0.513

High

326329

BPNT1
3'(2'),5'-bisphosphate nucleotidase 1

1

0

High-throughput

0.513

High

1162031

PLGT2
Protein O-glucosyltransferase 2

1

0

High-throughput

0.513

High

1162044

NPRL2
GATOR1 complex protein NPRL2

1

0

High-throughput

0.513

High

1162053

ISCA1
Iron-sulfur cluster assembly 1 homolog, mitochondrial

1

0

High-throughput

0.513

High

1162071

CDIN1
CDAN1-interacting nuclease 1

1

0

High-throughput

0.513

High

581773

VCAM1
Vascular cell adhesion protein 1

1

1

Small-scale

0.512

High

983161

UBE3A
Ubiquitin-protein ligase E3A

1

6

High-throughput

0.508

High

1100062

INF2
Inverted formin-2

1

1

High-throughput

0.489

High

1121779

ANR39
Ankyrin repeat domain-containing protein 39

1

5

High-throughput

0.489

High

1162035

PK1L2
Polycystin-1-like protein 2

1

4

High-throughput

0.489

High

1162037

WDR5B
WD repeat-containing protein 5B

1

4

High-throughput

0.489

High

1162045

DNJB3
DnaJ homolog subfamily B member 3

1

2

High-throughput

0.489

High

1162052

NPAS1
Neuronal PAS domain-containing protein 1

1

3

High-throughput

0.489

High

170673

AXIN1
Axin-1

1

5

Small-scale

0.479

High

276655

IDHC
Isocitrate dehydrogenase [NADP] cytoplasmic

1

2

Small-scale

0.479

High

417321

ENOA
Alpha-enolase

1

1

Small-scale

0.479

High

900599

RHOA
Transforming protein RhoA

1

6

Small-scale

0.479

High

932753

EF1A1
Elongation factor 1-alpha 1

1

2

Small-scale

0.479

High

1041843

CUL3
Cullin-3

1

16

High-throughput

0.479

High

1056052

NBR1
Next to BRCA1 gene 1 protein

1

1

High-throughput

0.479

High

1066277

KIF14
Kinesin-like protein KIF14

1

15

High-throughput

0.479

High

1088013

DUS6
Dual specificity protein phosphatase 6

1

4

Small-scale

0.479

High

1162042

ARRD4
Arrestin domain-containing protein 4

1

4

Small-scale

0.479

High

1162046

KAT6A
Histone acetyltransferase KAT6A

1

4

Small-scale

0.479

High

1162050

NLRP3
NACHT, LRR and PYD domains-containing protein 3

1

19

Small-scale

0.479

High

1162057

NLRP1
NACHT, LRR and PYD domains-containing protein 1

1

20

Small-scale

0.479

High

1162059

PKHA4
Pleckstrin homology domain-containing family A member 4

1

10

High-throughput

0.479

High

1162063

NLRC4
NLR family CARD domain-containing protein 4

1

20

Small-scale

0.479

High

1162068

TES
Testin

1

4

High-throughput

0.479

High

1162069

TNR6B
Trinucleotide repeat-containing gene 6B protein

1

4

High-throughput

0.479

High

795543

AL3B1
Aldehyde dehydrogenase family 3 member B1

1

0

High-throughput

0.458

High

1162065

TMOD3
Tropomodulin-3

1

6

Small-scale

0.437

High

1108467

NSN5B
Putative NOL1/NOP2/Sun domain family member 5B

1

2

High-throughput

0.407

High

1162033

PKHG7
Pleckstrin homology domain-containing family G member 7

1

7

High-throughput

0.407

High

1162066

PP4RL
Putative serine/threonine-protein phosphatase 4 regulatory subunit 1-like

1

1

High-throughput

0.407

High

1162047

SNX21
Sorting nexin-21

2

0

High-throughput

0.328

High

935941

NOMO3
BOS complex subunit NOMO3

1

0

High-throughput

0.279

Low

971090

OC90
Otoconin-90

1

0

High-throughput

0.279

Low

1093076

INSC
Protein inscuteable homolog

1

0

High-throughput

0.279

Low

1162032

LYPD4
Ly6/PLAUR domain-containing protein 4

1

0

High-throughput

0.279

Low

1162067

CS025
UPF0449 protein C19orf25

1

0

High-throughput

0.279

Low

1162036

MGDP1
Magnesium-dependent phosphatase 1

1

0

High-throughput

0.249

Low

1162049

YI001
Uncharacterized protein FLJ30774

1

0

High-throughput

0.249

Low

1162040

CI163
Uncharacterized protein C9orf163

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024