HitPredict

Interactor 1: WWP2 (O00308)
NEDD4-like E3 ubiquitin-protein ligase WWP2 (EC 2.3.2.26) (Atrophin-1-interacting protein 2) (AIP2) (HECT-type E3 ubiquitin transferase WWP2) (WW domain-containing protein 2)
Gene: WWP2

Interactor 2: LAPM5 (Q13571)
Lysosomal-associated transmembrane protein 5 (Lysosomal-associated multitransmembrane protein 5) (Retinoic acid-inducible E3 protein)
Gene: LAPTM5

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35842443
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 870 Hs			1 262
+	Hs
		1039511 ITCH_HUMAN (1-870): 0: 902: 54.26		LAPM5_HUMAN (1-262): 2.03e-151: 424: 100.00
+	Hs
		1039515 WWP1_HUMAN (1-870): 0: 888: 58.38		LAPM5_HUMAN (1-262): 2.03e-151: 424: 100.00
+	Hs
		1039512 NED4L_HUMAN (5-867): 0: 785: 32.17		LAPM5_HUMAN (1-262): 2.03e-151: 424: 100.00
+	Hs
		808116 NEDD4_HUMAN (90-867): 0: 731: 35.94		LAPM5_HUMAN (1-262): 2.03e-151: 424: 100.00
+	Hs
		808158 NEDD4_HUMAN (90-867): 0: 731: 35.94		Q5TBB8_HUMAN (1-262): 2.03e-151: 424: 100.00
+	Mm
		808355 NEDD4_MOUSE (14-364): 2.31e-51: 196: 19.16		LAPM5_MOUSE (1-262): 4.27e-144: 405: 79.01
+	Hs
		1039518 SMUF2_HUMAN (1-363): 5.89e-43: 169: 17.62		LAPM5_HUMAN (1-262): 2.03e-151: 424: 100.00