HitPredict

Interactor 1: WWP2 (O00308)
NEDD4-like E3 ubiquitin-protein ligase WWP2 (EC 2.3.2.26) (Atrophin-1-interacting protein 2) (AIP2) (HECT-type E3 ubiquitin transferase WWP2) (WW domain-containing protein 2)
Gene: WWP2

Interactor 2: RPAP2 (Q8IXW5)
Putative RNA polymerase II subunit B1 CTD phosphatase RPAP2 (EC 3.1.3.16) (RNA polymerase II-associated protein 2)
Gene: RPAP2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.71	0.60	0.656

Property	Details
Experiments	25071155, 31048545, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 870 Hs			1 612
+	Hs
		1221346 ITCH_HUMAN (1-870): 0: 902: 54.26		RPAP2_HUMAN (1-612): 0: 916: 100.00
+	Hs
		1221359 WWP1_HUMAN (1-870): 0: 888: 58.38		RPAP2_HUMAN (1-612): 0: 916: 100.00
+	Hs
		808182 NEDD4_HUMAN (90-867): 0: 731: 35.94		RPAP2_HUMAN (1-612): 0: 916: 100.00