HitPredict

Interactor 1: DCA11 (Q8TEB1)
DDB1- and CUL4-associated factor 11 (WD repeat-containing protein 23)
Gene: DCAF11

Interactor 2: CSN5 (Q92905)
COP9 signalosome complex subunit 5 (SGN5) (Signalosome subunit 5) (EC 3.4.-.-) (Jun activation domain-binding protein 1)
Gene: COPS5

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.88	0.60	0.729

Property	Details
Experiments	28446751, 37689310, 31950832, 19615732, 21145461, 19295130
Identification Methods	affinity chromatography technology, proximity labelling technology, tandem affinity purification, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 546 Hs			1 334
+	Hs
		154692 GNB5_HUMAN (349-534): 4.65e-28: 117: 16.24		CSN5_HUMAN (1-334): 6.64e-131: 378: 100.00
+	Hs
		197067 PRP4_HUMAN (238-515): 4.91e-26: 113: 14.39		CSN5_HUMAN (1-334): 6.64e-131: 378: 100.00
+	Hs
		903414 WDR5_HUMAN (470-546): 1.74e-12: 70.6: 16.67		CSN5_HUMAN (1-334): 6.64e-131: 378: 100.00
+	Hs
		1272598 SKI8_HUMAN (186-384): 3.11e-09: 60.5: 29.70		CSN5_HUMAN (1-334): 6.64e-131: 378: 100.00
+	Sc
		797501 COPA_YEAST (387-546): 8.36e-24: 108: 13.94		RPN11_YEAST (39-333): 9.57e-75: 234: 29.14
+	Hs
		130829 WDR5_HUMAN (470-546): 1.74e-12: 70.6: 16.67		PSDE_HUMAN (50-331): 1.67e-79: 246: 31.51
+	Hs
		1138819 SNR40_HUMAN (65-291): 2.25e-44: 162: 12.86		MYSM1_HUMAN (39-172): 3.5e-29: 119: 23.29
+	Hs
		124819 WDR5_HUMAN (470-546): 1.74e-12: 70.6: 16.67		EIF3F_HUMAN (44-328): 3.25e-64: 208: 14.48