HitPredict

Interactor 1: PARD3 (Q8TEW0)
Partitioning defective 3 homolog (PAR-3) (PARD-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (CTCL tumor antigen se2-5) (PAR3-alpha)
Gene: PARD3

Interactor 2: LZTS2 (Q9BRK4)
Leucine zipper putative tumor suppressor 2 (hLZTS2) (Protein LAPSER1)
Gene: LZTS2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	29395067, 34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1356 Hs			1 669
+	Hs
		1137888 PARD3_HUMAN (1-1356): 0: 709: 100.00		MRCKA_HUMAN (328-609): 6.79e-09: 61.6: 11.68
+	Hs
		149091 PARD3_HUMAN (1-1356): 0: 709: 100.00		CTRO_HUMAN (327-578): 7.02e-09: 61.3: 16.36
+	Hs
		942374 DLG4_HUMAN (540-699): 1.03e-22: 107: 27.98		LZTS2_HUMAN (1-669): 6.28e-56: 203: 100.00
+	Hs
		280066 MPDZ_HUMAN (446-543): 1.36e-20: 101: 40.82		LZTS2_HUMAN (1-669): 6.28e-56: 203: 100.00
+	Mm
		1193537 SCRIB_MOUSE (432-1330): 2.26e-33: 142: 11.83		TSC1_MOUSE (48-630): 3.36e-32: 135: 13.67
+	Hs
		990922 ZO1_HUMAN (271-586): 1.19e-11: 72: 14.06		LZTS2_HUMAN (1-669): 6.28e-56: 203: 100.00
+	Mm
		1143516 DLG4_MOUSE (540-699): 7.89e-23: 107: 27.98		TSC1_MOUSE (48-630): 3.36e-32: 135: 13.67
+	Mm
		57139 DLG4_MOUSE (540-699): 7.89e-23: 107: 27.98		LZTS3_MOUSE (1-669): 3.91e-31: 131: 31.62
+	Hs
		1252557 LNX1_HUMAN (73-395): 1.66e-13: 77.4: 12.79		LZTS1_HUMAN (26-653): 2.54e-34: 140: 35.06
+	Mm
		250627 LNX1_MOUSE (130-385): 1.31e-14: 80.8: 15.33		PHLB1_MOUSE (8-631): 1.39e-27: 121: 11.73
+	Hs
		148925 MAGI3_HUMAN (61-1272): 3.28e-32: 139: 10.65		CTRO_HUMAN (327-578): 7.02e-09: 61.3: 16.36
+	Hs
		61867 LNX1_HUMAN (73-395): 1.66e-13: 77.4: 12.79		CC88B_HUMAN (60-668): 4.55e-16: 84.7: 12.48
+	Hs
		1145894 MAGI1_HUMAN (354-780): 1.36e-16: 88.1: 14.16		CP135_HUMAN (300-610): 1.6e-09: 63.5: 21.52
+	Hs
		149188 MAGI1_HUMAN (354-780): 1.36e-16: 88.1: 14.16		CTRO_HUMAN (327-578): 7.02e-09: 61.3: 16.36
+	Hs
		990832 ZO1_HUMAN (271-586): 1.19e-11: 72: 14.06		CGNL1_HUMAN (321-645): 5.23e-13: 74.7: 21.88
+	Hs
		149079 INADL_HUMAN (28-397): 1.09e-15: 85.1: 11.14		CTRO_HUMAN (327-578): 7.02e-09: 61.3: 16.36
+	Hs
		149084 LNX1_HUMAN (73-395): 1.66e-13: 77.4: 12.79		CTRO_HUMAN (327-578): 7.02e-09: 61.3: 16.36
+	Hs
		990845 ZO1_HUMAN (271-586): 1.19e-11: 72: 14.06		PLEC_HUMAN (327-659): 1.61e-09: 63.5: 20.77
+	Hs
		990862 ZO1_HUMAN (271-586): 1.19e-11: 72: 14.06		CP135_HUMAN (300-610): 1.6e-09: 63.5: 21.52
+	Hs
		148718 ZO1_HUMAN (271-586): 1.19e-11: 72: 14.06		CTRO_HUMAN (327-578): 7.02e-09: 61.3: 16.36