Protein: NUD18
8-oxo-dGDP phosphatase NUDT18 (EC 3.6.1.58) (2-hydroxy-dADP phosphatase) (7,8-dihydro-8-oxoguanine phosphatase) (MutT homolog 3) (Nucleoside diphosphate-linked moiety X motif 18) (Nudix motif 18)

Gene: NUD18, NUDT18
Organism: Homo sapiens
Interactions: 39
UniProt ID: Q6ZVK8

Gene Ontology (top 5):
GO:0005829 - cytosol
GO:0044715 - 8-oxo-dGDP phosphatase activity
GO:0044716 - 8-oxo-GDP phosphatase activity
GO:0044717 - 8-hydroxy-dADP phosphatase activity
GO:0046057 - dADP catabolic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1256875

MTNB
Methylthioribulose-1-phosphate dehydratase

3

0

High-throughput

0.643

High

646868

PUR6
Bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase

2

0

High-throughput

0.613

High

881785

DHYS
Deoxyhypusine synthase

2

0

High-throughput

0.613

High

892258

5NTC
Cytosolic purine 5'-nucleotidase

2

0

High-throughput

0.613

High

1256871

R3GEF
Guanine nucleotide exchange factor for Rab-3A

2

0

High-throughput

0.613

High

1256876

DHB14
L-fucose dehydrogenase

2

0

High-throughput

0.613

High

339087

NADK
NAD kinase

2

0

High-throughput

0.582

High

578671

GLNA
Glutamine synthetase

2

0

High-throughput

0.582

High

1090739

TRAF2
TNF receptor-associated factor 2

1

2

High-throughput

0.541

High

1256872

BACD1
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 1

1

2

High-throughput

0.541

High

1150657

TRBP2
RISC-loading complex subunit TARBP2

1

0

High-throughput

0.536

High

323449

TRI37
E3 ubiquitin-protein ligase TRIM37

1

0

High-throughput

0.518

High

346737

CAVN2
Caveolae-associated protein 2

1

0

High-throughput

0.518

High

618055

K1C15
Keratin, type I cytoskeletal 15

1

0

High-throughput

0.518

High

733875

DCTD
Deoxycytidylate deaminase

1

0

High-throughput

0.518

High

960463

PSME3
Proteasome activator complex subunit 3

1

0

High-throughput

0.518

High

961611

PHS
Pterin-4-alpha-carbinolamine dehydratase

1

0

High-throughput

0.518

High

1131922

GNMT
Glycine N-methyltransferase

1

0

High-throughput

0.518

High

1256873

TIFA
TRAF-interacting protein with FHA domain-containing protein A

1

0

High-throughput

0.518

High

1256877

KR412
Keratin-associated protein 4-12

1

0

High-throughput

0.518

High

1256880

RWDD1
RWD domain-containing protein 1

1

0

High-throughput

0.518

High

142012

FCN1
Ficolin-1

1

0

High-throughput

0.513

High

1256869

KCD17
BTB/POZ domain-containing protein KCTD17

1

2

High-throughput

0.494

High

1256870

PAPD5
Terminal nucleotidyltransferase 4B

1

1

High-throughput

0.479

High

1256881

CUTC
Copper homeostasis protein cutC homolog

1

0

High-throughput

0.460

High

109154

G4U4J3
Terminal nucleotidyltransferase 4B

1

1

High-throughput

0.407

High

751328

DUT
Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial

2

0

High-throughput

0.334

High

1256874

EVI5L
EVI5-like protein

2

0

High-throughput

0.334

High

1256883

PRAF1
Prenylated Rab acceptor protein 1

2

0

High-throughput

0.334

High

1256882

TE2IP
Telomeric repeat-binding factor 2-interacting protein 1

1

0

High-throughput

0.299

High

1256879

NAT9
Alpha/beta-tubulin-N-acetyltransferase 9

1

0

High-throughput

0.292

High

284683

KHDR3
KH domain-containing, RNA-binding, signal transduction-associated protein 3

1

0

High-throughput

0.282

High

354233

ZBED1
E3 SUMO-protein ligase ZBED1

1

0

High-throughput

0.282

High

799947

COIL
Coilin

1

0

High-throughput

0.282

High

1130633

GSE1
Genetic suppressor element 1

1

0

High-throughput

0.282

High

1256878

KXDL1
KxDL motif-containing protein 1

1

0

High-throughput

0.282

High

133525

ACATN
Acetyl-coenzyme A transporter 1

1

0

High-throughput

0.279

Low

326183

FSBP
Fibrinogen silencer-binding protein

1

0

High-throughput

0.257

Low

1256884

RA54B
DNA repair and recombination protein RAD54B

1

0

High-throughput

0.251

Low


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Last updated: 11Aug2025