HitPredict

Interactor 1: Q8VD35 (Q8VD35)
Orthodenticle homeobox 2 (Otx2 protein)
Gene: Otx2

Interactor 2: ZBTB3 (Q91X45)
Zinc finger and BTB domain-containing protein 3
Gene: ZBTB3

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.481

Property	Details
Experiments	20211142
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific GO:0005634 - nucleus
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 289 Mm			1 518
+	Mm
		1246768 Q8R0B5_MOUSE (1-289): 4.77e-71: 222: 96.63		ZBTB3_MOUSE (1-518): 1.42e-103: 322: 100.00
+	Hs
		70969 OTX1_HUMAN (1-289): 5.31e-39: 141: 46.07		ZBT42_HUMAN (1-470): 8.98e-76: 246: 31.79
+	Hs
		641515 PAX6_HUMAN (5-250): 1.42e-34: 131: 24.39		ZBT10_HUMAN (5-488): 5.81e-52: 191: 18.88
+	Hs
		822661 LHX1_HUMAN (3-237): 1.5e-33: 128: 22.57		ZBT10_HUMAN (5-488): 5.81e-52: 191: 18.88
+	Hs
		1077276 ALX1_HUMAN (2-197): 2.59e-37: 136: 28.14		ZN300_HUMAN (83-245): 4.33e-21: 98.7: 4.55
+	Hs
		197831 CRX_HUMAN (1-289): 5.69e-41: 145: 46.91		PRD16_HUMAN (377-504): 2.34e-11: 68.8: 21.88
+	Hs
		197727 CRX_HUMAN (1-289): 5.69e-41: 145: 46.91		Q5THT1_HUMAN (6-119): 1.96e-12: 66.6: 35.65
+	Hs
		686458 OTX1_HUMAN (1-289): 5.31e-39: 141: 46.07		KLH26_HUMAN (4-121): 3.03e-11: 67.8: 34.45
+	Hs
		538743 HXB2_HUMAN (6-236): 5.94e-34: 128: 20.35		PRD16_HUMAN (377-504): 2.34e-11: 68.8: 21.88
+	Hs
		941913 PITX1_HUMAN (16-259): 8.79e-35: 129: 26.42		KLH26_HUMAN (4-121): 3.03e-11: 67.8: 34.45
+	Hs
		882160 GSC_HUMAN (36-128): 2.04e-16: 79: 46.81		PRD16_HUMAN (377-504): 2.34e-11: 68.8: 21.88