Interactor 1: NSE1 (Q8WV22)
Non-structural maintenance of chromosomes element 1 homolog (Non-SMC element 1 homolog) (EC 2.3.2.27)
Gene: NSMCE1

Interactor 2: NSE3 (Q96MG7)
Non-structural maintenance of chromosomes element 3 homolog (Non-SMC element 3 homolog) (Hepatocellular carcinoma-associated protein 4) (MAGE-G1 antigen) (Melanoma-associated antigen G1) (Necdin-like protein 2)
Gene: NSMCE3

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.97 1.00 0.986

The method score is based on:

Property Details
Experiments 26186194, 28514442, 29225034, 33961781, 37071682, 20864041, 18086888, 26910052, 27427983, 21364888, 32389690
Identification Methods affinity chromatography technology, pull down, cross-linking study, x-ray crystallography, two hybrid, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation, molecular sieving, tandem affinity purification
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains MAGE~SMC_Nse1
Common GO terms GO:0000724 - double-strand break repair via homologous recombination
GO:0000781 - chromosome, telomeric region
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0016925 - protein sumoylation
and 4 others

more...

Homologous interactions 6

Homologous interactions

Color coding for hit scores

1 266
Hs

1 304
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Dm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024