HitPredict

Interactor 1: RN138 (Q8WVD3)
E3 ubiquitin-protein ligase RNF138 (EC 2.3.2.27) (Nemo-like kinase-associated RING finger protein) (NLK-associated RING finger protein) (hNARF) (RING finger protein 138) (RING-type E3 ubiquitin transferase RNF138)
Gene: RNF138

Interactor 2: ZRAN1 (Q9UGI0)
Ubiquitin thioesterase ZRANB1 (EC 3.4.19.12) (TRAF-binding domain-containing protein) (hTrabid) (Zinc finger Ran-binding domain-containing protein 1)
Gene: ZRANB1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35944360
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0016055 - Wnt signaling pathway GO:0046872 - metal ion binding
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 245 Hs			1 708
+	Hs
		1354997 RN114_HUMAN (16-241): 4.34e-36: 129: 30.53		ZRAN1_HUMAN (1-697): 0: 987: 100.00
+	Hs
		1354988 TRAF6_HUMAN (12-245): 1.55e-33: 128: 16.25		ZRAN1_HUMAN (1-697): 0: 987: 100.00
+	Hs
		585089 RO52_HUMAN (6-157): 6.92e-32: 123: 17.11		ZRAN1_HUMAN (1-697): 0: 987: 100.00
+	Hs
		1304163 RING2_HUMAN (2-188): 8.11e-29: 112: 18.72		ZRAN1_HUMAN (1-697): 0: 987: 100.00
+	Hs
		1313379 TRAF4_HUMAN (8-207): 1.85e-27: 111: 13.14		ZRAN1_HUMAN (1-697): 0: 987: 100.00
+	Hs
		1349590 KCMF1_HUMAN (147-236): 1.38e-25: 105: 32.22		ZRAN1_HUMAN (1-697): 0: 987: 100.00
+	Hs
		988032 RING1_HUMAN (2-74): 3.94e-21: 92.7: 27.40		ZRAN1_HUMAN (1-697): 0: 987: 100.00
+	Hs
		1151641 TRAF6_HUMAN (12-245): 1.55e-33: 128: 16.25		OTU7B_HUMAN (322-701): 2.32e-127: 400: 25.54
+	Hs
		1255810 TRAF6_HUMAN (12-245): 1.55e-33: 128: 16.25		OTU7A_HUMAN (322-701): 5.77e-122: 388: 26.33
+	Hs
		1024691 TRAF3_HUMAN (2-245): 1.23e-28: 115: 14.69		OTU7B_HUMAN (322-701): 2.32e-127: 400: 25.54
+	Mm
		70745 TRAF3_MOUSE (2-245): 1.13e-28: 115: 14.69		OTU7B_MOUSE (322-701): 5.79e-124: 391: 25.78
+	Hs
		599703 RN166_HUMAN (5-244): 4.23e-40: 140: 29.58		TNAP3_HUMAN (392-651): 2.48e-93: 308: 35.74
+	Hs
		599755 RN114_HUMAN (16-241): 4.34e-36: 129: 30.53		TNAP3_HUMAN (392-651): 2.48e-93: 308: 35.74
+	Hs
		599753 TRAF6_HUMAN (12-245): 1.55e-33: 128: 16.25		TNAP3_HUMAN (392-651): 2.48e-93: 308: 35.74
+	Mm
		936229 TRAF6_MOUSE (12-227): 4.49e-33: 127: 15.77		TNAP3_MOUSE (392-651): 2.36e-92: 306: 36.10
+	Hs
		599727 TRIM5_HUMAN (5-160): 2.04e-28: 113: 14.91		TNAP3_HUMAN (392-651): 2.48e-93: 308: 35.74
+	Hs
		1290109 TRAF6_HUMAN (12-245): 1.55e-33: 128: 16.25		RNF31_HUMAN (29-410): 7.77e-78: 271: 15.73
+	Hs
		834828 RING2_HUMAN (2-188): 8.11e-29: 112: 18.72		RBP2_HUMAN (35-380): 3.46e-21: 101: 9.86