HitPredict

Interactor 1: 5HT3C (Q8WXA8)
5-hydroxytryptamine receptor 3C (5-HT3-C) (5-HT3C) (Serotonin receptor 3C)
Gene: HTR3C

Interactor 2: EDA (Q92838)
Ectodysplasin-A (Ectodermal dysplasia protein) (EDA protein) [Cleaved into: Ectodysplasin-A, membrane form; Ectodysplasin-A, secreted form]
Gene: EDA

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	26186194, 28514442
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 447 Hs			1 391
+	Hs
		677159 ACHB4_HUMAN (7-442): 1.84e-139: 410: 19.18		EDA_HUMAN (235-391): 7.4e-58: 195: 100.00
+	Hs
		687006 ACHA3_HUMAN (33-369): 8.03e-138: 406: 26.90		EDA_HUMAN (235-391): 7.4e-58: 195: 100.00
+	Hs
		798549 ACHA4_HUMAN (30-399): 2.48e-135: 404: 24.27		EDA_HUMAN (235-391): 7.4e-58: 195: 100.00
+	Hs
		989638 ACHD_HUMAN (36-373): 5.05e-121: 364: 25.93		EDA_HUMAN (235-391): 7.4e-58: 195: 100.00