Protein: NOG2
Nucleolar GTP-binding protein 2

Gene: NOG2
Organism: Saccharomyces cerevisiae S288C
Interactions: 217
UniProt ID: P53742

Gene Ontology (top 5):
GO:0000055 - ribosomal large subunit export from nucleus
GO:0003924 - GTPase activity
GO:0005525 - GTP binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

816875

NUG1
Nuclear GTP-binding protein NUG1

11

2

Small-scale

0.973

High

803898

CIC1
Proteasome-interacting protein CIC1

7

3

Small-scale

0.956

High

923194

ARX1
Probable metalloprotease ARX1

18

5

Small-scale

0.762

High

918936

PESC
Pescadillo homolog

17

2

Small-scale

0.761

High

782397

RPF2
Ribosome biogenesis protein RPF2

13

3

Small-scale

0.758

High

513394

RL23B
Large ribosomal subunit protein uL14B

2

2

Small-scale

0.754

High

818256

NSA2
Ribosome biogenesis protein NSA2

11

5

Small-scale

0.754

High

923190

NOG1
Nucleolar GTP-binding protein 1

11

10

Small-scale

0.754

High

806638

RIX1
Pre-rRNA-processing protein RIX1

11

1

Small-scale

0.753

High

923232

IF6
Eukaryotic translation initiation factor 6

10

5

Small-scale

0.752

High

923213

BUD20
Bud site selection protein 20

9

2

Small-scale

0.751

High

919542

SDA1
Protein SDA1

9

2

Small-scale

0.748

High

673581

NLE1
Ribosome assembly protein 4

8

7

Small-scale

0.744

High

750117

MRT4
Ribosome assembly factor MRT4

8

6

Small-scale

0.744

High

923224

NOP53
Ribosome biogenesis protein NOP53

9

4

Small-scale

0.744

High

827568

RLP7
Ribosome biogenesis protein RLP7

8

10

Small-scale

0.741

High

923212

RLP24
Ribosome biogenesis protein RLP24

8

5

Small-scale

0.740

High

923222

MDN1
Midasin

7

5

Small-scale

0.740

High

923220

RRS1
Regulator of ribosome biosynthesis

7

4

Small-scale

0.737

High

864177

ALB1
Ribosome biogenesis protein ALB1

6

2

Small-scale

0.726

High

923204

ERB1
Ribosome biogenesis protein ERB1

6

8

Small-scale

0.723

High

684802

RL5
Large ribosomal subunit protein uL18

5

5

Small-scale

0.709

High

805005

IPI1
Pre-rRNA-processing protein IPI1

5

2

Small-scale

0.709

High

923191

HAS1
ATP-dependent RNA helicase HAS1

5

19

Small-scale

0.704

High

410261

RL25
Large ribosomal subunit protein uL23

5

3

Small-scale

0.702

High

433256

RL17A
Large ribosomal subunit protein uL22A

5

4

Small-scale

0.702

High

923175

IPI3
Pre-rRNA-processing protein IPI3

4

10

Small-scale

0.686

High

923177

NOP15
Ribosome biogenesis protein 15

4

8

Small-scale

0.676

High

918039

CGR1
rRNA-processing protein CGR1

4

2

Small-scale

0.672

High

923227

MAK21
Ribosome biogenesis protein MAK21

3

9

High-throughput

0.670

High

570095

RL3
Large ribosomal subunit protein uL3

6

3

Small-scale

0.663

High

601098

RL8A
Large ribosomal subunit protein eL8A

5

6

Small-scale

0.641

High

531829

RL4A
Large ribosomal subunit protein uL4A

3

9

Small-scale

0.640

High

682352

SPB4
ATP-dependent rRNA helicase SPB4

3

18

High-throughput

0.640

High

689091

RL16A
Large ribosomal subunit protein uL13A

3

7

Small-scale

0.640

High

745097

AFG2
ATPase family gene 2 protein

3

4

Small-scale

0.640

High

923197

RRP17
Ribosomal RNA-processing protein 17

3

1

High-throughput

0.640

High

435260

RS3
Small ribosomal subunit protein uS3

1

4

High-throughput

0.618

High

433768

RL26A
Large ribosomal subunit protein uL24A

4

6

Small-scale

0.617

High

527324

HSP72
Heat shock protein SSA2

2

6

High-throughput

0.601

High

814356

NOC2
Nucleolar complex protein 2

2

1

High-throughput

0.594

High

923018

DBP6
ATP-dependent RNA helicase DBP6

2

10

High-throughput

0.594

High

504340

RL31A
Large ribosomal subunit protein eL31A

3

6

Small-scale

0.585

High

383344

RL28
Large ribosomal subunit protein uL15

2

2

Small-scale

0.584

High

503413

RL11A
Large ribosomal subunit protein uL5A

2

7

Small-scale

0.584

High

677222

SPB1
27S pre-rRNA

2

7

High-throughput

0.584

High

746651

DRS1
ATP-dependent RNA helicase DRS1

2

15

Small-scale

0.584

High

781235

RL14A
Large ribosomal subunit protein eL14A

2

4

Small-scale

0.584

High

791082

NOP4
Nucleolar protein 4

2

3

High-throughput

0.584

High

795832

YBC8
UPF0642 protein YBL028C

2

1

Small-scale

0.584

High

813710

ECM1
Shuttling pre-60S factor ECM1

2

1

Small-scale

0.584

High

826713

DSN1
Kinetochore-associated protein DSN1

2

1

High-throughput

0.584

High

830152

NOP2
25S rRNA

2

4

Small-scale

0.584

High

863860

RL17B
Large ribosomal subunit protein uL22B

2

4

High-throughput

0.584

High

864488

MTR4
ATP-dependent RNA helicase DOB1

2

7

Small-scale

0.584

High

879831

RL37A
Large ribosomal subunit protein eL37A

2

3

Small-scale

0.584

High

923182

RL34A
Large ribosomal subunit protein eL34A

2

4

Small-scale

0.584

High

865268

LSM8
LSM2-LSM8 complex subunit LSM8

2

0

High-throughput

0.577

High

394782

EF1A
Elongation factor 1-alpha

1

3

High-throughput

0.575

High

734165

EF2
Elongation factor 2

1

5

High-throughput

0.575

High

524728

HSP71
Heat shock protein SSA1

2

6

High-throughput

0.571

High

545771

SSB1
Ribosome-associated molecular chaperone SSB1

2

9

High-throughput

0.552

High

722138

XPO1
Exportin-1

1

5

High-throughput

0.536

High

885041

RL4B
Large ribosomal subunit protein uL4B

1

9

High-throughput

0.536

High

917441

PRP43
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP43

1

5

High-throughput

0.536

High

923228

RL7B
Large ribosomal subunit protein uL30B

1

10

High-throughput

0.536

High

432653

RL7A
Large ribosomal subunit protein uL30A

2

10

Small-scale

0.533

High

432890

RL9A
Large ribosomal subunit protein uL6A

2

3

Small-scale

0.533

High

434059

RL33A
Large ribosomal subunit protein eL33A

2

2

Small-scale

0.533

High

434417

RL15A
Large ribosomal subunit protein eL15A

2

2

Small-scale

0.533

High

434625

RL22A
Large ribosomal subunit protein eL22A

2

5

Small-scale

0.533

High

511461

RL43B
Large ribosomal subunit protein eL43B

2

4

Small-scale

0.533

High

513733

RL2A
Large ribosomal subunit protein uL2A

2

6

Small-scale

0.533

High

514040

RL18B
Large ribosomal subunit protein eL18B

2

4

Small-scale

0.533

High

569834

RL30
Large ribosomal subunit protein eL30

2

3

Small-scale

0.533

High

712635

RL8B
Large ribosomal subunit protein eL8B

2

6

High-throughput

0.533

High

923189

RL21A
Large ribosomal subunit protein eL21A

2

2

Small-scale

0.533

High

923219

RS10A
Small ribosomal subunit protein eS10A

2

3

High-throughput

0.533

High

751446

CBF5
H/ACA ribonucleoprotein complex subunit CBF5

2

1

High-throughput

0.521

High

744139

BRR2
Pre-mRNA-splicing helicase BRR2

1

9

Small-scale

0.508

High

751765

PRP8
Pre-mRNA-splicing factor 8

1

1

Small-scale

0.508

High

518094

SSBP1
Single-stranded nucleic acid-binding protein

1

2

High-throughput

0.501

High

809381

STM1
Suppressor protein STM1

1

0

High-throughput

0.493

High

923192

CLU
Clustered mitochondria protein 1

1

1

High-throughput

0.489

High

923202

KU80
ATP-dependent DNA helicase II subunit 2

1

1

High-throughput

0.489

High

678714

PAT1
Deadenylation-dependent mRNA-decapping factor PAT1

1

0

High-throughput

0.486

High

739258

PRP21
Pre-mRNA-splicing factor PRP21

1

0

High-throughput

0.486

High

817136

RSMB
Small nuclear ribonucleoprotein-associated protein B

1

0

High-throughput

0.486

High

923207

YL456
Pyridoxamine 5'-phosphate oxidase YLR456W homolog

1

0

High-throughput

0.486

High

923209

PRP11
Pre-mRNA-splicing factor PRP11

1

0

High-throughput

0.486

High

923230

SNU66
66 kDa U4/U6.U5 small nuclear ribonucleoprotein component

1

0

Small-scale

0.486

High

149885

RS9A
Small ribosomal subunit protein uS4A

1

3

High-throughput

0.479

High

427388

RLA0
Large ribosomal subunit protein uL10

1

6

Small-scale

0.479

High

436089

RS13
Small ribosomal subunit protein uS15

1

2

High-throughput

0.479

High

442039

RS14A
Small ribosomal subunit protein uS11A

1

1

High-throughput

0.479

High

512570

RS6A
Small ribosomal subunit protein eS6A

1

5

High-throughput

0.479

High

515297

RL35A
Large ribosomal subunit protein uL29A

1

2

Small-scale

0.479

High

534128

MAK16
Protein MAK16

1

2

High-throughput

0.479

High

594494

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

1

High-throughput

0.479

High

646488

RAD53
Serine/threonine-protein kinase RAD53

1

2

High-throughput

0.479

High

647177

RPC2
DNA-directed RNA polymerase III subunit RPC2

1

2

High-throughput

0.479

High

674753

RS2
Small ribosomal subunit protein uS5

1

5

High-throughput

0.479

High

679927

CDC48
Cell division control protein 48

1

3

High-throughput

0.479

High

689582

RS7A
Small ribosomal subunit protein eS7A

1

2

High-throughput

0.479

High

707801

TF2B
Transcription initiation factor IIB

1

4

High-throughput

0.479

High

727222

HS104
Heat shock protein 104

1

3

High-throughput

0.479

High

735090

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

1

High-throughput

0.479

High

758238

URB1
Nucleolar pre-ribosomal-associated protein 1

1

1

High-throughput

0.479

High

763098

RRP1
Ribosomal RNA-processing protein 1

1

4

High-throughput

0.479

High

779303

CENPA
Histone H3-like centromeric protein CSE4

1

7

High-throughput

0.479

High

792173

GBLP
Small ribosomal subunit protein RACK1

1

15

High-throughput

0.479

High

793508

MAK5
ATP-dependent RNA helicase MAK5

1

17

High-throughput

0.479

High

798279

ENP1
Essential nuclear protein 1

1

1

High-throughput

0.479

High

805071

RPF1
Ribosome production factor 1

1

2

High-throughput

0.479

High

808873

UME6
Transcriptional regulatory protein UME6

1

1

High-throughput

0.479

High

822421

PRS4
26S proteasome regulatory subunit 4 homolog

1

3

Small-scale

0.479

High

825390

BMT5
25S rRNA

1

1

High-throughput

0.479

High

844561

UTP10
U3 small nucleolar RNA-associated protein 10

1

2

High-throughput

0.479

High

849995

LOC1
60S ribosomal subunit assembly/export protein LOC1

1

1

Small-scale

0.479

High

850127

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

1

3

High-throughput

0.479

High

917539

NSA1
Ribosome biogenesis protein NSA1

1

2

High-throughput

0.479

High

923173

JJJ1
J protein JJJ1

1

11

Small-scale

0.479

High

923176

NOP13
Nucleolar protein 13

1

3

High-throughput

0.479

High

923178

APJ1
J domain-containing protein APJ1

1

3

High-throughput

0.479

High

923179

ORC1
Origin recognition complex subunit 1

1

2

High-throughput

0.479

High

923181

H3
Histone H3

1

7

High-throughput

0.479

High

923184

NOP3
Serine/arginine

1

9

High-throughput

0.479

High

923193

GIS1
Transcriptional activator/repressor GIS1

1

1

High-throughput

0.479

High

923196

MTQ2
eRF1 methyltransferase catalytic subunit MTQ2

1

1

High-throughput

0.479

High

923198

DHR1
Probable ATP-dependent RNA helicase DHR1

1

5

High-throughput

0.479

High

923200

PUF6
Pumilio homology domain family member 6

1

2

Small-scale

0.479

High

923203

UTP14
U3 small nucleolar RNA-associated protein 14

1

3

High-throughput

0.479

High

923205

RRP5
rRNA biogenesis protein RRP5

1

3

High-throughput

0.479

High

923206

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

1

High-throughput

0.479

High

923208

NOC4
Nucleolar complex protein 4

1

9

High-throughput

0.479

High

923211

NOC3
Nucleolar complex-associated protein 3

1

5

High-throughput

0.479

High

923214

NOP12
Nucleolar protein 12

1

7

High-throughput

0.479

High

923215

BRX1
Ribosome biogenesis protein BRX1

1

13

High-throughput

0.479

High

923216

SGO1
Shugoshin

1

2

High-throughput

0.479

High

923218

TMA16
Translation machinery-associated protein 16

1

2

High-throughput

0.479

High

923221

NIP7
60S ribosome subunit biogenesis protein NIP7

1

1

High-throughput

0.479

High

923223

YTM1
Ribosome biogenesis protein YTM1

1

11

High-throughput

0.479

High

923225

YL11B
Transposon Ty1-LR1 Gag-Pol polyprotein

1

1

High-throughput

0.479

High

923226

RRP6
Exosome complex exonuclease RRP6

1

2

High-throughput

0.479

High

923229

DBP10
ATP-dependent RNA helicase DBP10

1

11

High-throughput

0.479

High

923235

RL11B
Large ribosomal subunit protein uL5B

1

7

High-throughput

0.479

High

865405

URB2
Nucleolar pre-ribosomal-associated protein 2

1

0

High-throughput

0.458

High

923174

SQS1
Protein SQS1

1

0

High-throughput

0.458

High

923195

FIN1
Filament protein FIN1

1

0

Small-scale

0.458

High

923217

MCA1
Metacaspase-1

1

0

High-throughput

0.458

High

923231

RUVB2
RuvB-like protein 2

1

0

High-throughput

0.458

High

923234

YL363
Uncharacterized protein YLR363W-A

1

0

High-throughput

0.458

High

393120

HSP82
ATP-dependent molecular chaperone HSP82

1

5

High-throughput

0.445

High

486501

TBA3
Tubulin alpha-3 chain

1

2

High-throughput

0.445

High

597230

BIP
Endoplasmic reticulum chaperone BiP

1

1

High-throughput

0.445

High

740198

RPN2
26S proteasome regulatory subunit RPN2

1

3

High-throughput

0.445

High

742101

HSP7F
Heat shock protein homolog SSE1

1

8

High-throughput

0.445

High

795901

LSM2
LSM complex subunit LSM2

1

1

High-throughput

0.445

High

803635

RPN1
26S proteasome regulatory subunit RPN1

1

3

High-throughput

0.445

High

811363

CAJ1
Protein CAJ1

1

1

High-throughput

0.445

High

817919

IMB4
Importin subunit beta-4

1

6

High-throughput

0.445

High

819404

SSB2
Ribosome-associated molecular chaperone SSB2

1

9

High-throughput

0.445

High

923188

NU116
Nucleoporin NUP116/NSP116

1

1

Small-scale

0.445

High

383824

RS17A
Small ribosomal subunit protein eS17A

1

3

High-throughput

0.437

High

409763

RL24A
Large ribosomal subunit protein eL24A

1

5

Small-scale

0.437

High

415039

RL39
Large ribosomal subunit protein eL39

1

1

Small-scale

0.437

High

434182

RL36A
Large ribosomal subunit protein eL36A

1

3

Small-scale

0.437

High

455188

RS19A
Small ribosomal subunit protein eS19A

1

3

High-throughput

0.437

High

503166

RS22A
Small ribosomal subunit protein uS8A

1

2

High-throughput

0.437

High

503823

RL27A
Large ribosomal subunit protein eL27A

1

3

Small-scale

0.437

High

511248

RL20B
Large ribosomal subunit protein eL20B

1

3

Small-scale

0.437

High

513139

RS8A
Small ribosomal subunit protein eS8A

1

3

High-throughput

0.437

High

514760

RS18A
Small ribosomal subunit protein uS13A

1

2

High-throughput

0.437

High

515145

RL19B
Large ribosomal subunit protein eL19

1

5

Small-scale

0.437

High

597525

EF3A
Elongation factor 3A

1

4

High-throughput

0.437

High

747502

RSSA1
Small ribosomal subunit protein uS2A

1

6

High-throughput

0.437

High

753505

RS3A1
Small ribosomal subunit protein eS1A

1

3

High-throughput

0.437

High

778462

RS27A
Small ribosomal subunit protein eS27A

1

2

High-throughput

0.437

High

792551

RL32
Large ribosomal subunit protein eL32

1

1

Small-scale

0.437

High

795131

NU170
Nucleoporin NUP170

1

2

High-throughput

0.437

High

802303

RS20
Small ribosomal subunit protein uS10

1

3

High-throughput

0.437

High

812534

LAA1
AP-1 accessory protein LAA1

1

2

High-throughput

0.437

High

825888

RL34B
Large ribosomal subunit protein eL34B

1

4

High-throughput

0.437

High

835850

RL10
Large ribosomal subunit protein uL16

1

5

Small-scale

0.437

High

865322

MTNB
Methylthioribulose-1-phosphate dehydratase

1

2

High-throughput

0.437

High

874449

RS12
Small ribosomal subunit protein eS12

1

2

High-throughput

0.437

High

879873

RL38
Large ribosomal subunit protein eL38

1

2

Small-scale

0.437

High

902659

RL9B
Large ribosomal subunit protein uL6B

1

3

High-throughput

0.437

High

918312

RL26B
Large ribosomal subunit protein uL24B

1

6

High-throughput

0.437

High

923180

RL22B
Large ribosomal subunit protein eL22B

1

5

High-throughput

0.437

High

923183

NUM1
Nuclear migration protein NUM1

1

3

High-throughput

0.437

High

923185

RS15
Small ribosomal subunit protein uS19

1

2

High-throughput

0.437

High

923187

RL6A
Large ribosomal subunit protein eL6A

1

2

Small-scale

0.437

High

923199

VMS1
tRNA endonuclease VMS1

1

4

High-throughput

0.437

High

923210

VAM6
Vacuolar morphogenesis protein 6

1

4

High-throughput

0.437

High

923233

RL13A
Large ribosomal subunit protein eL13A

1

4

Small-scale

0.437

High

386812

TBB
Tubulin beta chain

1

0

High-throughput

0.426

High

836821

MPG1
Mannose-1-phosphate guanyltransferase

1

0

High-throughput

0.426

High

923186

UBC7
Ubiquitin-conjugating enzyme E2 7

1

2

High-throughput

0.417

High

453721

PYR1
Multifunctional protein URA2

1

1

High-throughput

0.407

High

554033

TCPA
T-complex protein 1 subunit alpha

1

1

High-throughput

0.407

High

579830

HSC82
ATP-dependent molecular chaperone HSC82

1

5

High-throughput

0.407

High

752573

HSP78
Heat shock protein 78, mitochondrial

1

2

High-throughput

0.407

High

755139

GCN1
eIF-2-alpha kinase activator GCN1

1

5

High-throughput

0.407

High

763472

MDJ1
DnaJ homolog 1, mitochondrial

1

4

High-throughput

0.407

High

823280

JEM1
DnaJ-like chaperone JEM1

1

2

High-throughput

0.407

High

825465

LYS12
Homoisocitrate dehydrogenase, mitochondrial

1

1

High-throughput

0.407

High

865579

ARP3
Actin-related protein 3

2

0

High-throughput

0.328

High

515379

RS32B
Small ribosomal subunit protein eS32B

1

0

High-throughput

0.249

Low

558821

CAF20
Cap-associated protein CAF20

1

0

High-throughput

0.249

Low

751233

DOM34
Protein DOM34

1

0

High-throughput

0.249

Low

365138

KPYK1
Pyruvate kinase 1

1

0

High-throughput

0.232

Low

471423

ARO1
Pentafunctional AROM polypeptide [Includes: 3-dehydroquinate synthase

1

0

High-throughput

0.232

Low

592409

VATB
V-type proton ATPase subunit B

1

0

High-throughput

0.232

Low

808807

LYS9
Saccharopine dehydrogenase [NADP(+), L-glutamate-forming]

1

0

High-throughput

0.232

Low

865024

TCPQ
T-complex protein 1 subunit theta

1

0

High-throughput

0.232

Low

923201

HSP31
Glutathione-independent glyoxalase HSP31

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025