HitPredict

Interactor 1: CSN9 (Q8WXC6)
COP9 signalosome complex subunit 9 (CSN acidic protein) (CSNAP) (Myeloma-overexpressed gene 2 protein)
Gene: COPS9

Interactor 2: CSN3 (Q9UNS2)
COP9 signalosome complex subunit 3 (SGN3) (Signalosome subunit 3) (JAB1-containing signalosome subunit 3)
Gene: COPS3

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.90	0.60	0.737

Property	Details
Experiments	26186194, 26456823, 28514442, 32034103, 33961781, 37071682
Identification Methods	affinity chromatography technology, pull down, cross-linking study, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0008180 - COP9 signalosome
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 57 Hs			1 423
+	Dm
		1177417 CSN9_DROME (1-55): 6.43e-17: 68.5: 62.07		CSN3_DROME (1-423): 2.7e-116: 348: 50.79
+	Hs
		897280 CSN9_HUMAN (1-57): 2.2e-22: 82: 100.00		CSN2_HUMAN (21-393): 1.28e-87: 275: 12.23
+	Hs
		1263346 CSN9_HUMAN (1-57): 2.2e-22: 82: 100.00		CSN4_HUMAN (1-397): 3.04e-62: 208: 15.87