HitPredict

Interactor 1: PSPC1 (Q8WXF1)
Paraspeckle component 1 (Paraspeckle protein 1)
Gene: PSPC1

Interactor 2: MK67I (Q9BYG3)
MKI67 FHA domain-interacting nucleolar phosphoprotein (Nucleolar phosphoprotein Nopp34) (Nucleolar protein interacting with the FHA domain of pKI-67) (hNIFK)
Gene: NIFK

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	NOPS~RRM_1, RRM_1~RRM_1
Common GO terms	GO:0003723 - RNA binding GO:0005654 - nucleoplasm GO:0005737 - cytoplasm
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 523 Hs			1 293
+	Mm
		857359 PSPC1_MOUSE (1-523): 9.43e-82: 265: 97.33		TIA1_MOUSE (40-289): 5.79e-47: 163: 12.50
+	Hs
		1031404 PSPC1_HUMAN (1-523): 7.74e-85: 273: 100.00		PABP4_HUMAN (35-225): 7.16e-41: 151: 14.66
+	Hs
		516608 PSPC1_HUMAN (1-523): 7.74e-85: 273: 100.00		PABP1_HUMAN (35-225): 1.96e-40: 150: 14.14
+	Hs
		516471 PABP1_HUMAN (4-522): 4.65e-70: 237: 14.16		TIAR_HUMAN (39-289): 7.08e-48: 165: 13.44
+	Mm
		665745 PABP1_MOUSE (4-522): 6.83e-70: 237: 14.16		TIA1_MOUSE (40-289): 5.79e-47: 163: 12.50
+	Hs
		516495 PABP1_HUMAN (4-522): 4.65e-70: 237: 14.16		PABP4_HUMAN (35-225): 7.16e-41: 151: 14.66
+	Hs
		516339 PABP1_HUMAN (4-522): 4.65e-70: 237: 14.16		PABP1_HUMAN (35-225): 1.96e-40: 150: 14.14
+	Hs
		516689 PABP1_HUMAN (4-522): 4.65e-70: 237: 14.16		PABP3_HUMAN (35-234): 1.42e-37: 142: 13.00
+	Hs
		1020299 PSPC1_HUMAN (1-523): 7.74e-85: 273: 100.00		ELAV2_HUMAN (38-128): 7.23e-24: 101: 26.37
+	Hs
		516635 PABP1_HUMAN (4-522): 4.65e-70: 237: 14.16		PABP5_HUMAN (49-222): 2.56e-35: 132: 12.07
+	Mm
		1207997 NONO_MOUSE (45-523): 1.13e-66: 224: 57.83		CSTFT_MOUSE (46-219): 1.38e-37: 142: 20.11
+	Hs
		516730 PABP1_HUMAN (4-522): 4.65e-70: 237: 14.16		PUF60_HUMAN (31-234): 4.14e-30: 120: 17.96
+	Hs
		1073607 PSPC1_HUMAN (1-523): 7.74e-85: 273: 100.00		SF3B4_HUMAN (26-283): 2.83e-17: 83.3: 11.92
+	Ce
		71809 B3GWA1_CAEEL (57-366): 1.18e-59: 208: 40.97		O45577_CAEEL (29-278): 4.11e-41: 146: 16.54
+	Hs
		516484 PABP1_HUMAN (4-522): 4.65e-70: 237: 14.16		ELAV2_HUMAN (38-128): 7.23e-24: 101: 26.37
+	Hs
		613467 SFPQ_HUMAN (53-523): 3.05e-59: 210: 54.14		SF3B4_HUMAN (26-283): 2.83e-17: 83.3: 11.92
+	Hs
		1020306 PABP5_HUMAN (86-416): 1.38e-52: 184: 16.90		ELAV2_HUMAN (38-128): 7.23e-24: 101: 26.37
+	Hs
		474034 PABP5_HUMAN (86-416): 1.38e-52: 184: 16.90		PAB4L_HUMAN (1-123): 1.69e-22: 97.5: 21.95